Anti-Specific Protein-1 Antibody抗體 | 貨號Y105547

產品介紹: 妊娠特異性糖蛋白1(Pregnancy Specific Glycoprotein 1) 與人類妊娠特異性糖蛋白（PSG）反應，PSG是一組密切相關的分泌糖蛋白，其在胎兒來源的胎盤合體滋養細胞(placental syncytiotrophoblast cells)中高度表達。 PSG通常在滋養層(trophoblast origin)起源的腫瘤（hydatidiform mole葡萄胎，choriocarcinoma絨毛膜癌）中表達。 它們代表了母體血液中最豐富的胎兒蛋白質(fetal protein)。 11個人PSG基因（PSG1-PSG11）與CEACAM基因家族的癌胚抗原（CEA）相關細胞粘附分子（CEACAM）基因一起形成。 PSG刺激單核細胞分泌TH2型細胞因子。 顯示CD9代表鼠PSG17的單核細胞受體。 PSG被認為在懷孕期間調節母體免疫系統，從而保護半胎型胎兒免於排斥。

Product Name	Anti-Specific Protein-1 Antibody
Description	Pregnancy Specific Glycoprotein 1 reacts with human pregnancy-specific glycoproteins (PSG), a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
Subtype	polyclonal
Application	other
Raised In	Rabbit
Immunogen	Specific protein-1
Guarantee	abm guarantees that all our Anti-Specific Protein-1 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Formulation	Liquid
Quantity	1 ml
Clone	Polyclonal Antibody
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	PBS, pH 7.4 with 0.02% sodium azide.
Purity	Affinity purified
Species Reactivity	other