Innovex Fc受體阻斷劑 | Innovex Fc Receptor Block貨號NB309
Innovex Fc受體阻斷劑 (Innovex Fc Receptor Block) | 貨號NB309

產品介紹: Fc受體阻滯劑 (Innovex Fc Receptor Block) ,先進和獨特的功能;阻斷人和動物細胞中的Fc受體。是準確的淋巴瘤,白血病和黑色素瘤分型以及無背景Kappa和λ染色的必需品。Innovex Fc Receptor Block是一種基於peptide based的技術,不含抗體,血清,免疫球蛋白,免疫球蛋白片段或鏈黴蛋白酶。目的為阻斷所有白血球細胞(white blood cells),淋巴瘤(lymphomas)和黑色素瘤(melanomas)中存在的Fc受體(Fc Receptors)。在室溫下對人體組織/細胞進行30分鐘的孵育步驟;動物組織/細胞孵育45分鐘至1小時。消除白血球細胞,淋巴組織,細胞株(血液和骨髓),黑色素瘤和其他表達Fc的腫瘤的假陽性染色,確保准確的淋巴瘤和白血病分型。

Fc受體(Fc Receptors)也在大多數腫瘤(tumors)上表達。阻斷Fc受體對於淋巴(lymphoid)和腫瘤組織(tumor tissues)和細胞的準確分型至關重要。 Fc受體染色通過細胞上存在的Fc受體與初級和/或第二抗體的Fc區的結合而發生。 Fc受體阻斷劑可用於IHC(冷凍和石蠟),免疫螢光(immunofluorescence),流式細胞術(flow cytometry)和原位雜交(in-situ hybridization)。對於活細胞和功能測定,建議使用Azide-Free Fc Block (貨號NB335)。
產品特點:
- Blocks Fc Receptors in both human and animal cells
- 30 minute incubation step at room temperature for human tissues/cells
- 45 minutes to 1-hour incubation for animal tissues/cells
- Eliminates false positive staining of white blood cells, lymphoid tissues, cytosmears (blood & bone marrow), melanoma tumors and other Fc expressing tumors
- Insures accurate lymphoma and leukemia typing
- liminates negative control staining of lymphomas, lymphoid tissues, and blood and bone marrow smears
- Eliminates false positive staining for Kappa and Lambda staining
- Eliminates false positive staining of Reed Sternberg cells
- A must for CD markers staining in IHC, immunofluorescence
- A must for CD phenotyping via flow cytometry
- A must for Immunoglobulins (Igs) staining via IHC, flow cytometry and immunofluorescence
- A must for kappa and lambda staining
文獻資料
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395339/
