SB 203580抑制劑 | CAS#152121-47-6貨號1712-5

SB 203580-A MAP Kinase inhibitor

產品描述：SB 203580 為A MAP Kinase inhibitor ，具細胞滲透性(Cell-permeable)。 p38促分裂原活化蛋白激酶（MAP激酶）的選擇性抑制劑（對於SAPK2a / p38和SAPK2b /p38β2，IC 50值分別為50和500nM）。 顯示出比LCK，GSK3β和PKBα高100-500倍的選擇性。

Alternate Name	[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole
Appearance	White to off-white solid
CAS #	152121-47-6
Molecular Formula	C₂₁H₁₆FN₃OS
Molecular Weight	377.43
Purity	≥99% by HPLC
Solubility	DMSO (>50 mg/ml) or warm ethanol (12 mg/ml)
SMILES	CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
InChi	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
InChi Key	CDMGBJANTYXAIV-UHFFFAOYSA-N
PubChem CID	176155
MDL Number	MFCD00922198
Handling	Protect from air and light