Rotenone殺蟲劑 | CAS #83-79-4貨號2248
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特點
A mitochondrial electron transport chain inhibitor
產品介紹: 一種廣譜性殺蟲劑 (insecticide) ，具有細胞滲透性 (cell-permeable) 和腦透性。作為線粒體電子傳遞鏈抑制劑 (mitochondrial electron transport chain inhibitor)（在複合物I中IC 50 =1.7-2.2μM）。通過心肌肌漿網 (cardiac sarcoplasmic reticulum) 抑制NADH氧化（IC 50 = 3.4nM）。神經毒性劑 (Neurotoxic agent) 也已成功用於在體外切片培養模型中再現帕金森樣 (Parkinsons-like) 特徵。
| Alternate Name | (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-][1]benzopyran-6(6aH)-one |
| Appearance | White to yellow solid |
| CAS # | 83-79-4 |
| Molecular Formula | C₂₃H₂₂O₆ |
| Molecular Weight | 394.42 |
| Purity | ≥95% by HPLC |
| Solubility | DMSO (100 mM) or EtOH (5 mM) |
| SMILES | CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC |
| InChi | InChI=1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1 |
| InChi Key | JUVIOZPCNVVQFO-HBGVWJBISA-N |
| PubChem CID | 6758 |
| MDL Number | MFCD09025614 |
| Handling | Protect from light and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |