EZCyp™活性人類重組細胞色素P450 3A4 | 貨號7872

EZCyp™ Active Human Cytochrome P450 3A4-Unique, cost-effective CYP3A4 catalytic system with active recombinant human CYP3A4 coexpressed with the active NADPH reductase in a semipermeable membrane system.

產品描述：細胞色素P450 3A4（Cytochrome P450 3A4, CYP3A4，EC 1.14.13.157）是microsomal xenobiotic metabolism enzymes微粒體異生物質代謝酶的細胞色素P450單氧化酶（CYP）家族的成員。 CYP是負責I期生物轉化反應的membrane-bound hemeproteins膜結合血紅素蛋白，其中親脂性藥物和其他異生物質化合物轉化為更親水的產物以促進體內排泄。 CYP3A4在liver肝臟和intestines腸中以高水平表達，其中它催化極其多種結構上不同的配體的氧化。 人類常用的所有小分子藥物中有一半以上被CYP3A4代謝。 BioVision的EZCyp™3A4是一種透化和穩定的酵母粉末製劑，含有重組人CYP 3A4和在相同製劑中表達的重組人P450 NADPH氧化還原酶。

Alternate Name	Cytochrome P450 3A, Cytochrome P450 3A4, Cyt3A4, CYPIIIA, CYPIIIA4, CYP3A, CYP3A4, Microsomal cytochrome P450 3A4, active CYP3A, human cyp3a, human CYP3A4, recombinant human CYP3A4
Gene Symbol	CYP3A4
Gene ID	1576
Accession #	P08684
Source	Pichia pastoris
Appearance	Dry powder
Physical Form Description	Lyophilized powder
Molecular Weight	55 KDa
Purity by	NA
Endotoxin Level	NA
Biological Activity	NA
Reconstitution Instructions	100 mM Potassium Phosphate buffer, pH 7.7
Handling	Centrifuge the vial prior to opening.