登革E蛋白的抗DIII結構域抗體 | Anti-DIII domain of Dengue E protein [DV10] 貨號Ab00245-10.0
Fc Silent™ Antibodies: Turning down the background noise 只要訊號不要雜訊 (Engineered Fc Domain)
Alternative Name(s) of Target: Envelope protein
Immunogen: Made by immortalizing IgG-expressing B cells Dengue Virus (DENV) patients after primary or secondary infection.
Specificity: This antibody specifically recognizes an epitope in the DIII domain of E protein of DENV-1, DENV-2, DENV-3 and DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient recovered from a primary DENV-2 infection and neutralises infection.
Antibody first published in: Beltramello et al. The human immune response to Dengue Virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe. 2010 Sep 16;8(3):271-83. PMID:20833378
Purification: Protein A affinity purified
Supplied in: PBS only.
Storage Recommendation: Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Concentration: 1 mg /ml.