澱粉樣蛋白β42（人）ELISA試劑盒 | 貨號E4288

Amyloid Beta 42 (Human) ELISA Kit

產品描述：澱粉樣蛋白β（Aβ或Abeta）表示36-43個氨基酸的肽，其作為阿爾茨海默病患者腦中發現的澱粉樣斑塊的主要成分，與阿爾茨海默病密切相關。該肽由澱粉樣蛋白前體蛋白（APP）產生，其被β分泌酶和γ分泌酶切割以產生Aβ。 Aβ分子可聚集形成柔性可溶性低聚物，其可以以幾種形式存在。現在認為某些錯誤折疊的寡聚體（稱為“種子”）可以誘導其他Aβ分子也採取錯誤折疊的寡聚體形式，導致類似於朊病毒感染的鍊式反應。種子或產生的澱粉樣蛋白斑對神經細胞有毒。與阿爾茨海默病有關的另一種蛋白質tau蛋白也形成這種朊病毒樣錯誤折疊的寡聚體，並且有證據表明錯誤折疊的Aβ可誘導tau錯誤折疊。 BioVision的澱粉樣蛋白β42ELISA試劑盒是一種夾心ELISA檢測，用於定量測量血清，血漿和細胞培養上清液中的人澱粉樣蛋白β42。顏色密度與從樣品中捕獲的人澱粉樣蛋白β42的量成比例。

Cat # +Size	E4288-100
Size	100 assays
Kit Summary	• Detection method- Absorbance (450 nm) • Species reactivity- Human • Application- quantitative measurement of Amyloid beta 42 in human serum, plasma, tissue homogenates and other biological fluids.
Detection Method	Absorbance (450 nm)
Species Reactivity	Human
Applications	This ELISA kit is used for quantitative measurement of Amyloid beta 42 in human serum, plasma, tissue homogenates and other biological fluids.
Features & Benefits	• Easy, convenient and time-saving method to measure the level of Amyloid beta 24 alpha in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids. • Detection Range: 15.62 – 1000 pg/ml • Sensitivity: < 9.375 pg/ml • Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10% • Cross Reactivity: No significant cross-reactivity or interference between this analyte and its analogues was observed.
Kit Components	• Micro ELISA Plate • Lyophilized Standard • Sample / Standard dilution buffer • Biotin- detection antibody (Concentrated) • Antibody dilution buffer • HRP-Streptavidin Conjugate (SABC) • SABC dilution buffer • TMB substrate • Stop Solution • Wash buffer (25X) • Plate sealers