基質金屬肽酶9(MMP-9)-MMP-9活性重組蛋白 | 貨號7867-500
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基質金屬肽酶9(MMP-9)-MMP-9活性重組蛋白 | 貨號7867-500
>95% Pure, Active, Human Recombinant, MMP-9/Matrix Metallopeptidase 9. A Protein involved in breakdown of extracellular matrix
產品描述:基質金屬肽酶9(MMP-9)也稱為92kDa IV型膠原酶,92kDa明膠酶或明膠酶B,是由於其在癌症生物學,自身免疫疾病和其他病症中的基本作用而研究最多的MMP。 該酶降解包括明膠,IV型和V型膠原蛋白以及彈性蛋白在內的各種底物。 MMP-9在結構上是多結構域金屬酶,由前結構域,催化結構域,明膠結合結構域,金屬結合結構域和羧基末端血紅素結合蛋白樣結構域組成。 該活性人MMP-9由催化結構域,明膠結合結構域和金屬結合結構域(AA107-457)組成。 蛋白質在大腸桿菌中表達並使用專有技術純化和重折疊。
Alternate Name | Matrix Metalloproteinase-9, Gelatinase B, 92 kDa Type IV Collagenase, MMP9, CLG4B, GELB, MANDP2 |
Gene Symbol | MMP-9 |
Gene ID | 4319 |
Accession # | P14780 |
Source | E. coli |
Appearance | Lyophilized |
Physical Form Description | Lyophilized from a proprietary buffer |
Molecular Weight | 39 kDa (aa 107-457 + NT His Tag) |
Purity by SDS-PAGE | ≥95% |
Reconstitution Instructions | Reconstitute with pre-chilled 30% Glycerol solution (in dH2O) to 10 U/µl and incubate on ice until it completely dissolves. Aliquot and store the reconstituted MMP-9 at -20°C. Stable for 2 months after reconstitution. |
Handling | Centrifuge the vial prior to opening. |