α-GalCer | α-Galactosylceramide 貨號2152 (Abcam ab144262)
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特點
α-Galactosylceramide 250ug-1000ug包裝 | 貨號2152 (Abcam ab144262)
A specific ligand for human and mouse natural killer T (NKT) cells
產品介紹: α-GalCer是人和小鼠自然殺傷T（NKT）細胞的特異性配體; 通過鼠體內實驗（包括皮下植入模型和肝和肺中的轉移模型）顯示出有效的抗腫瘤活性。 據報導KRN7000在小鼠感染性疾病，自身免疫性疾病和移植物宿主病中表現出各種免疫學作用。
| Alternate Name | alpha-Galactosylceramide; αGalCer; KRN7000; (2S,3S,4R)-1-O-(α-D-galactosyl)-N-hexacosanoyl-2-amino- 1,3,4-octadecanetriol |
| Appearance | White to off-white solid |
| CAS # | 158021-47-7 |
| Molecular Formula | C₅₀H₉₉NO₉ |
| Molecular Weight | 858.32 |
| Purity | ≥96% by NMR |
| Solubility | For In vivo assay: Use 5.6% sucrose, 0.75% L-histidine and 0.5% Tween20 with heating at 60-80 ̊C. For In vitro assay: should be dissolved in DMSO at the concentration of 1 mg/ml with heating at 60-80 ̊C . The solution of 1mg/ml in DMSO can be diluted by P |
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