CD31重組蛋白 | T/B cell surface proteins BioWorld貨號NCP0199

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CD31重組蛋白 | T/B cell surface proteins BioWorld貨號NCP0199
CD31 Recombinant Protein
CD31(血小板內皮細胞粘附分子-1:Platelet Endothelial Cell Adhesion Molecule-1, PECAM-1)是細胞粘附分子( cell adhesion molecules) Ig 超家族的成員,由循環血小板(circulating platelets)、單核細胞(monocytes)、嗜中性粒細胞(neutrophils)、一些 T 細胞和內皮細胞表達( endothelial cells),並調節細胞粘附(cell adhesion)、內皮細胞遷移(endothelial cell migration)和血管生成(angiogenesis)。在各種刺激(例如機械或氧化應激)下,CD31 在細胞質羧基末端尾部的 Tyr686 上被磷酸化,推測是由 Src 家族成員引起的。酪氨酸磷酸化( tyrosine phosphorylation )介導與許多包含 SH2 結構域的結合夥伴的關聯,例如 PI3 激酶( PI3 kinase)、SHIP、PLCγ 和 SHP-2。因此,CD31 充當各種信號分子的scaffold 。

| Product Name | CD31 Recombinant Protein |
| Catalog No. | NCP0199 |
| Swiss-Prot | P16284 |
| Host | E.coli |
| Tag | His-tag in C-terminal |
| Restriction sites | NdeI-XhoI |
| Background | |
| Soluble | PBS, 4M Urea, PH7.4 |
| Purification&Purity | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
| Concentration | ≥0.5mg/ml |
Product Name :
CD31 Recombinant Protein
Swiss-Prot :
P16284
Host :
E.coli
Tag :
≥0.5mg/ml
Restriction sites :
NdeI-XhoI
Soluble :
PBS, 4M Urea, PH7.4
Purification&Purity :
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Expression vector :
pet-22b(+)
BiowMW :
~63kDa
