乙醇酸測定試劑盒 | 貨號K2022-100 Abcam (Biovision)

Glycolic Acid assay kit

乙醇酸（Glycolic Acid , GA），也稱為羥乙酸(Hydroxyl Acetic Acid)是最小的α羥基酸 (alpha hydroxy acid)。儘管它以小劑量用於幾種打算用於皮膚的皮膚護理產品中，但其急性劑量可能導致皮膚和眼睛刺激。吞嚥會產生腎毒性，其毒性是由於其轉化為草酸(oxalic acid)，然後草酸與鈣沉澱形成晶體，導致腎臟組織損傷(renal tissue injury)。 Glycolic Acid (GA)也是乙二醇代謝的主要下游代謝產物，血清中濃度高於8 mM表示需要進行血液透析(hemodialysis)。通常，血清GA水平處於非常低的微摩爾範圍（約2 µM）。 BioVision的乙醇酸測定試劑盒(BioVision’s Glycolic Acid assay kit)是一種功能強大的一步式測定法，用於測定血清中的Glycolic Acid (GA)。 GA檢測試劑會代謝Glycolic Acid (GA)，從而導致形成中間體。然後，在存在GA酶混合物的情況下，中間體將非螢光GA探針轉換為螢光產物，該產物在Ex / Em = 535/587 nm下測量。該試劑盒可定量低至30 pmol的GA。此產品需由儀器進行定量 ELISA儀器設備請按此。

Cat # +Size	K2022-100
Size	100 assays
Kit Summary	BioVision’s Glycolic Acid assay kit is a robust, one step plate based assay for the measurement of GA in serum. The GA Detection Reagent metabolizes GA leading to the formation of an intermediate. The intermediate in the presence of GA enzyme mix then converts the non-fluorescent GA probe to a fluorescent product, which is measured at Ex/Em = 535/587 nm. This kit can quantify as low as 30 pmol of GA.
Detection Method	Fluorescence (Ex/Em = 535/587 nm)
Species Reactivity	All
Applications	Quantification of Glycolic acid
Features & Benefits	• One step plate based assay for the measurement of GA in serum • Robust
Kit Components	GA Probe GA Detection Reagent GA Standard GA Assay Buffer GA Enzyme Mix