{"id":9727,"date":"2017-04-26T14:45:16","date_gmt":"2017-04-26T06:45:16","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=9727"},"modified":"2022-07-22T13:32:38","modified_gmt":"2022-07-22T05:32:38","slug":"wnv-envelope-protein-diii%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%94-%e8%b2%a8%e8%99%9fab00674-3-0","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=9727","title":{"rendered":"WNV Envelope protein DIII\u55ae\u682a\u6297\u9ad4 | \u8ca8\u865fAb00674-3.0"},"content":{"rendered":"

Fc Silent\u2122 Antibodies: Turning down the background noise<\/strong> \u53ea\u8981<\/strong>\u8a0a<\/strong>\u865f\u4e0d\u8981\u96dc<\/strong>\u8a0a (Engineered Fc Domain)<\/strong><\/p>\n

Anti-WNV Envelope protein DIII [E16]<\/strong><\/p>\n

Absoluted Antibody \u63d0\u4f9b\u4e00\u7cfb\u5217\u6297\u9ad4\u5546\u54c1\uff0c\u5176\u4e2dFc Silent\u2122 Antibodies\u7cfb\u5217\uff1b\u80fd\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027Fc\u7d50\u5408\u3002Fc Silent\u2122\u6280\u8853\uff0c\u70ba\u61c9\u7528\u751f\u7269\u5de5\u7a0b\u6280\u8853\uff0c\u5c07Fc receptors (Fc\u03b3R, FcR)\u9ede\u7a81\u8b8a\uff0c\u9032\u800c\u4e2d\u6b62\u6297\u9ad4\u8207ADCC\u7684\u529f\u80fd\uff1b\u6709\u6548\u964d\u4f4eFc\u6240\u9020\u6210\u7684\u80cc\u666f\u8a0a\u865f\u3002Fc Silent\u2122\u6297\u9ad4\u61c9\u7528\u65bc\u514d\u75ab\u7d30\u80de\u6642flow cytometry\u3001immunohistochemistry (IHC)\u8cc7\u6599\u986f\u793a\uff0c\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027\u4e4bFc\u7d50\u5408\uff0c\u6240\u9020\u6210\u7684\u80cc\u666f\u503c\u3002(\u8a02\u8cfc\u6297\u9ad4\u524d\uff0c\u8acb\u78ba\u8a8d\u9078\u64c7\u6297\u9ad4\u662f\u5426\u6709Fc Silent\u2122\u4fee\u98fe\u6a19\u8a8c)<\/p>\n

\u7522\u54c1\u4ecb\u7d39<\/strong> WNV Envelope protein DIII<\/strong>\u55ae\u682a\u6297\u9ad4<\/strong> | <\/strong>\u8ca8\u865f<\/strong>Ab00674-3.0<\/strong><\/p>\n

Description:<\/strong> Recombinant monoclonal antibody to WNV Envelope protein DIII. Manufactured using AbAb\u2019s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma E16.
\nSpecies and Isotype:<\/strong>\u00a0<\/strong>Mouse IgG2b, kappa
\nClone Number:<\/strong>\u00a0<\/strong>E16
\nUniProt Accession Number of Target Protein:<\/strong>\u00a0<\/strong>
\nPublished Application(s):<\/strong>\u00a0<\/strong>NTRL; crystallography
\nPublished Species Reactivity:<\/strong>\u00a0<\/strong>West Nile virus
\nImmunogen:<\/strong>\u00a0<\/strong>
\nSpecificity:<\/strong>\u00a0<\/strong>This antibody binds to the Envelope protein DIII domain of West Nile virus.
\nApplication Notes:<\/strong>\u00a0<\/strong>This antibody binds to the DIII domain of the Envelope protein of West Nile Virus and neutralizes infection.
\nAntibody First Published in:<\/strong>\u00a0<\/strong>
\nDowd et al. A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus PLoS Pathog. 2011 Jun; 7(6): e1002111.\u00a0PMID:21738473<\/a>\u00a0Note on publication:<\/strong>\u00a0<\/strong>Describes the characterization of the neutralizing effect of this antibody.<\/p>\n

Purification:<\/strong>\u00a0<\/strong>Protein A affinity purified
\nSupplied in:<\/strong>\u00a0<\/strong>PBS with preservative (0.02% Proclin 300)
\nStorage Recommendation:<\/strong>\u00a0<\/strong>Store at 4\u00b0C for up to 3 months. For longer term storage aliquot into small volumes and store at -20\u00b0C
\nConcentration:<\/strong>\u00a0<\/strong>See vial label.<\/p>\n

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