{"id":54983,"date":"2026-08-06T14:49:46","date_gmt":"2026-08-06T06:49:46","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=54983"},"modified":"2026-08-06T14:49:59","modified_gmt":"2026-08-06T06:49:59","slug":"biotin-hpdp-cas-129179-83-5-apexbio%e8%b2%a8%e8%99%9fa8008","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=54983","title":{"rendered":"Biotin-HPDP | CAS# 129179-83-5 APExBIO\u8ca8\u865fA8008"},"content":{"rendered":"

APExBIO\u7cfb\u5217\u5546\u54c1 ->>Biotin-HPDP\u00a0<\/span><\/span><\/span><\/span><\/strong>
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APExBIO Technology LLC \u662f\u4e00\u5bb6\u9818\u5148\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5291 (Small Molecule Inhibitors)\/\u6d3b\u5316\u5291 (Activators)\u3001\u5316\u5408\u7269\u5eab( Compound Libraries)\u3001\u80dc\u80bd(Peptides)\u3001\u6aa2\u6e2c\u8a66\u5291\u76d2(Assay Kits)\u3001\u87a2\u5149\u6a19\u8a18(Fluorescent Label)\u3001\u9176(Enzymes)\u3001\u4fee\u98fe\u6838\u82f7\u9178(Modified Nucleotides)\u3001mRNA \u5408\u6210\u4ee5\u53ca\u5404\u7a2e\u5206\u5b50\u751f\u7269\u5b78\u5de5\u5177\u7684\u4f9b\u61c9\u5546\u3002APExBIO\u63d0\u4f9b\u5ee3\u6cdb\u7684\u7522\u54c1\u7dda\uff0c\u6db5\u84cb 20 \u591a\u500b\u4e0d\u540c\u7684\u7814\u7a76\u9818\u57df\uff0c\u4f8b\u5982\u764c\u75c7(cancer)\u3001\u514d\u75ab\u5b78(immunology)\u3001\u795e\u7d93\u79d1\u5b78(neurosciences)\u3001\u7d30\u80de\u51cb\u4ea1(apoptosis)\u548c\u8868\u89c0\u907a\u50b3\u5b78(epigenetics)\u7b49\u3002\u516c\u53f8\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u5fb7\u5dde\u4f11\u58eb\u9813USA (Houston, Texas)\uff0c\u81f4\u529b\u65bc\u670d\u52d9\u5168\u7403\u5ba2\u6236\u3002\u9ad8\u5ea6\u91cd\u8996\u7522\u54c1\u54c1\u8cea\u3002\u6240\u6709\u7522\u54c1\u5747\u9075\u5faa\u56b4\u683c\u7684\u751f\u7522\u6307\u5357\uff0c\u4e26\u9644\u6709\u5206\u6790\u8b49\u66f8\u3001HPLC\u3001\u8cea\u8b5c(Mass Spectrum)\u548cHMNR\u4ee5\u53ca\u9ad4\u5916\u9a57\u8b49(in vitro validation)\u3002 APExBIO\u7522\u54c1\u5df2\u88ab\u300aNature\u300b\u3001\u300aCell\u300b\u548c\u300aScience\u300b\u7b49\u773e\u591a\u9802\u7d1a\u540c\u884c\u8a55\u5be9\u671f\u520a\u5f15\u7528\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

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Biotin-HPDP| CAS# 129179-83-5 APExBIO\u8ca8\u865fA8008<\/a><\/span><\/p>\n

Sulfhydryl-reactive biotinylation reagent, pyridyldithiol-activated<\/p>\n

\u7522\u54c1\u4ecb\u7d39<\/span><\/strong><\/span><\/p>\n

Biotin-HPDP\uff08N-[6-(\u751f\u7269\u7d20\u91af\u80fa\u57fa)\u5df1\u57fa]-3\u2019-(2\u2019-\u5421\u5576\u57fa\u4e8c\u786b\u4ee3)\u4e19\u91af\u80fa\uff09\u662f\u4e00\u7a2e\u5df0\u57fa\u53cd\u61c9\u6027\u751f\u7269\u7d20\u5316\u8a66\u5291 (sulfhydryl-reactive biotinylation)\u3002\u6b64\u8a66\u5291\u4e0d\u6eb6\u65bc\u6c34\uff0c\u5728\u52a0\u5165\u6c34\u76f8\u53cd\u61c9\u7cfb\u7d71\u4e4b\u524d\uff0c\u9700\u5148\u6eb6\u89e3\u65bc\u9069\u5b9c\u7684\u6eb6\u5291\uff08\u5982\u4e8c\u7532\u57fa\u4e9e\u781c [DMSO] \u6216\u4e8c\u7532\u57fa\u7532\u91af\u80fa [DMF]\uff09\u4e2d\u3002 Biotin-HPDP \u7684\u7d50\u69cb\u5305\u542b\u4e00\u500b\u96d9\u74b0\u751f\u7269\u7d20\u74b0\u3001\u4e00\u500b\u9023\u63a5\u5728\u751f\u7269\u7d20\u620a\u9178\u5074\u93c8\u4e0a\u7684 1,6-\u4e8c\u6c28\u57fa\u5df1\u70f7\u9593\u9694\u81c2\uff0c\u4ee5\u53ca\u4f4d\u65bc\u8a72\u9593\u9694\u81c2\u672b\u7aef\u7684\u5df0\u57fa\u53cd\u61c9\u57fa\u5718\u3002 Biotin-HPDP \u672b\u7aef\u7684\u5421\u5576\u57fa\u4e8c\u786b\u9375\u57fa\u5718\u80fd( pyridyl disulfide group )\u5920\u8207\u86cb\u767d\u8cea\u6216\u5176\u4ed6\u5206\u5b50\u4e0a\u7684\u6e38\u96e2\u5df0\u57fa\u53cd\u61c9\uff0c\u5f62\u6210\u4e8c\u786b\u9375\u4e26\u91cb\u653e\u51fa\u5421\u5576-2-\u786b\u916e (pyridine-2-thione)\u3002 Biotin-HPDP \u8f03\u9577\u7684\u9593\u9694\u81c2\u6709\u52a9\u65bc\u4fee\u98fe\u5f8c\u7684\u5206\u5b50\u66f4\u597d\u5730\u8207\u89aa\u548c\u7d20\uff08avidin\uff09\u6216\u93c8\u9ef4\u89aa\u548c\u7d20\uff08streptavidin\uff09\u63a2\u91dd\u7d50\u5408\u3002<\/p>\n


\n\u2022 \u86cb\u767d\u8cea\u6a19\u8a18\uff0d\u5c0d\u7528\u65bc\u5404\u985e\u86cb\u767d\u8cea\u5206\u6790\u65b9\u6cd5\u7684\u6297\u9ad4\u6216\u5176\u4ed6\u86cb\u767d\u8cea\u9032\u884c\u751f\u7269\u7d20\u5316\u4fee\u98fe
\n\u2022 \u5df0\u57fa\u53cd\u61c9\u6027\uff0d\u53ef\u8207\u5df0\u57fa\uff08-SH\uff09\u53cd\u61c9\uff0c\u4f8b\u5982\u534a\u80f1\u80fa\u9178\uff08C\uff09\u7684\u5074\u93c8\u5df0\u57fa
\n\u2022 \u5421\u5576\u4e8c\u786b\u57fa\uff08Pyridyldithiol\uff09\u6d3b\u5316\uff0d\u53ef\u5728 pH 6.5 \u81f3 7.5 \u7684\u7de9\u885d\u6db2\uff08\u5982 PBS\uff09\u4e2d\u9032\u884c\u53cd\u61c9
\n\u2022 \u53ef\u9006\u6027\uff0d\u5f62\u6210\u7684\u4e8c\u786b\u9375\u53ef\u900f\u904e DTT \u6216\u5176\u4ed6\u9084\u539f\u5291\u65b7\u88c2
\n\u2022 \u6eb6\u89e3\u6027\uff0d\u4e0d\u6eb6\u65bc\u6c34\uff1b\u4f7f\u7528\u524d\u9808\u5148\u6eb6\u65bc DMSO \u6216 DMF\uff0c\u7136\u5f8c\u518d\u7528\u6c34\u6027\u7de9\u885d\u6db2\u7a00\u91cb
\n\u2022 \u4e2d\u9577\u5ea6\uff0d\u9593\u9694\u81c2\uff08spacer arm\uff09\u9577\u5ea6\u70ba 29.2 \u57c3\uff08\u00c5\uff09<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Physical Appearance<\/td>\nA solid<\/td>\n<\/tr>\n
Storage<\/td>\nStore at -20\u00b0C<\/td>\n<\/tr>\n
M.Wt<\/td>\n539.78<\/td>\n<\/tr>\n
Cas No.<\/td>\n129179-83-5<\/td>\n<\/tr>\n
Formula<\/td>\nC24<\/sub>H37<\/sub>N5<\/sub>O3<\/sub>S3<\/sub><\/td>\n<\/tr>\n
Synonyms<\/td>\nBiotinHPDP<\/td>\n<\/tr>\n
Solubility<\/td>\ninsoluble in H2O; \u226533.47 mg\/mL in DMSO; \u22658.29 mg\/mL in EtOH with ultrasonic<\/td>\n<\/tr>\n
Chemical Name<\/td>\n5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[6-[3-(pyridin-2-yldisulfanyl)propanoylamino]hexyl]pentanamide<\/td>\n<\/tr>\n
Canonical SMILES<\/td>\nC1C2C(C(S1)CCCCC(=O)NCCCCCCNC(=O)CCSSC3=CC=CC=N3)NC(=O)N2<\/td>\n<\/tr>\n
Shipping Condition<\/td>\nSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n
General tips<\/td>\nWe do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/div>\n
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APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/p>\n<\/div>\n<\/div>\n

https:\/\/www.apexbt.com<\/a><\/span><\/p>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n

\"\"\u8a98\u767c\u75be\u75c5\u6a21\u578b\u7522\u54c1<\/span><\/span><\/span><\/span><\/strong><\/span><\/p>\n