{"id":52019,"date":"2025-07-08T16:49:41","date_gmt":"2025-07-08T08:49:41","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=52019"},"modified":"2025-11-15T13:33:42","modified_gmt":"2025-11-15T05:33:42","slug":"%e9%bb%83%e8%8a%aa%e9%bb%83%e9%85%ae-astragalin-cas480-10-4-apexbio%e8%b2%a8%e8%99%9fn1897","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=52019","title":{"rendered":"\u9ec3\u82aa\u9ec3\u916e (Astragalin)| CAS#480-10-4 APExBIO\u8ca8\u865fN1897"},"content":{"rendered":"

\u5929\u7136\u7522\u54c1\u7cfb\u5217\u5546\u54c1->>\u9ec3\u82aa\u9ec3\u916e(Astragalin)<\/span>
\n<\/span><\/span><\/span><\/strong><\/p>\n

APExBIO Technology LLC \u662f\u4e00\u5bb6\u9818\u5148\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5291 (Small Molecule Inhibitors)\/\u6d3b\u5316\u5291(Activators)\u3001\u5316\u5408\u7269\u5eab( Compound Libraries)\u3001\u80dc\u80bd(Peptides)\u3001\u6aa2\u6e2c\u8a66\u5291\u76d2(Assay Kits)\u3001\u87a2\u5149\u6a19\u8a18(Fluorescent Label)\u3001\u9176(Enzymes)\u3001\u4fee\u98fe\u6838\u82f7\u9178(Modified Nucleotides)\u3001mRNA \u5408\u6210\u4ee5\u53ca\u5404\u7a2e\u5206\u5b50\u751f\u7269\u5b78\u5de5\u5177\u7684\u4f9b\u61c9\u5546\u3002APExBIO\u63d0\u4f9b\u5ee3\u6cdb\u7684\u7522\u54c1\u7dda\uff0c\u6db5\u84cb 20 \u591a\u500b\u4e0d\u540c\u7684\u7814\u7a76\u9818\u57df\uff0c\u4f8b\u5982\u764c\u75c7(cancer)\u3001\u514d\u75ab\u5b78(immunology)\u3001\u795e\u7d93\u79d1\u5b78(neurosciences)\u3001\u7d30\u80de\u51cb\u4ea1(apoptosis)\u548c\u8868\u89c0\u907a\u50b3\u5b78(epigenetics)\u7b49\u3002\u516c\u53f8\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u5fb7\u5dde\u4f11\u58eb\u9813USA (Houston, Texas)\uff0c\u81f4\u529b\u65bc\u670d\u52d9\u5168\u7403\u5ba2\u6236\u3002\u9ad8\u5ea6\u91cd\u8996\u7522\u54c1\u54c1\u8cea\u3002\u6240\u6709\u7522\u54c1\u5747\u9075\u5faa\u56b4\u683c\u7684\u751f\u7522\u6307\u5357\uff0c\u4e26\u9644\u6709\u5206\u6790\u8b49\u66f8\u3001HPLC\u3001\u8cea\u8b5c(Mass Spectrum)\u548cHMNR\u4ee5\u53ca\u9ad4\u5916\u9a57\u8b49(in vitro validation)\u3002 APExBIO\u7522\u54c1\u5df2\u88ab\u300aNature\u300b\u3001\u300aCell\u300b\u548c\u300aScience\u300b\u7b49\u773e\u591a\u9802\u7d1a\u540c\u884c\u8a55\u5be9\u671f\u520a\u5f15\u7528\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

<\/p>\n

\u9ec3\u82aa\u9ec3\u916e (Astragalin)| CAS#480-10-4 APExBIO\u8ca8\u865fN1897<\/a><\/span><\/p>\n

\u7522\u54c1\u4ecb\u7d39<\/span><\/strong><\/span><\/p>\n

\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u662f\u55dc\u9178\u6027\u7d30\u80de\u6d3b\u5316\u8da8\u5316\u56e0\u5b50-1 (eotaxin-1)\u3001PKC\u03b22\u78f7\u9178\u5316(PKC\u03b22 phosphorylation)\u3001NF-\u03baB\/MAPK\u548cPLC\u03b31\u6d3b\u5316\u7684\u6291\u5236\u5291\uff0c\u4e14\u8207\u6c27\u5316\u9176(oxidase)\u5448\u73fe\u5291\u91cf\u4f9d\u8cf4\u6027\u76f8\u95dc[1][2]\u3002
\n\u6c27\u5316\u58d3\u529b(Oxidative stress )\u662f\u6307\u7d30\u80de\u6b63\u5e38\u6c27\u5316\u9084\u539f\u72c0\u614b\u7684\u7d0a\u4e82\uff0c\u5176\u900f\u904e\u7522\u751f\u904e\u6c27\u5316\u7269(peroxides )\u548c\u81ea\u7531\u57fa(free radicals)\u800c\u5c0e\u81f4\u7d30\u80de\u6bd2\u6027\u4f5c\u7528\uff0c\u9019\u4e9b\u904e\u6c27\u5316\u7269\u548c\u81ea\u7531\u57fa\u6703\u640d\u5bb3\u7d30\u80de\u7684\u6240\u6709\u6210\u5206\u3002\u64da\u5831\u9053\uff0c\u6c27\u5316\u58d3\u529b(oxidative stress)\u53ef\u5c0e\u81f4\u7d30\u80de\u8a0a\u865f\u50b3\u5c0e\u6b63\u5e38\u6a5f\u5236\u7d0a\u4e82\uff0c\u4f8b\u5982\u764c\u75c7\u767c\u5c55(cancer development)\u3001\u5e15\u91d1\u68ee\u6c0f\u75c7(Parkinson’s disease)\u3001\u963f\u8332\u6d77\u9ed8\u75c7(Alzheimer’s disease)\u3001\u52d5\u8108\u7ca5\u72c0\u786c\u5316(atherosclerosis)\u3001passive cutaneous reactions\u3001\u767c\u708e(inflammation)\u3001\u5fc3\u81df\u8870\u7aed(heart failure)\u3001\u5fc3\u808c\u6897\u585e(myocardial infarction)\u3001\u942e\u72c0\u7d30\u80de\u75be\u75c5(Sickle Cell Disease, infection)\u3001\u611f\u67d3\u548c\u6162\u6027\u75b2\u52de\u75c7\u5019\u7fa4 (chronic fatigue syndrome) [1, 3]\u3002\u5728\u4eba\u985e\u9aa8\u95dc\u7bc0\u708e\u8edf\u9aa8\u7d30\u80de\u4e2d\uff0c\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u6291\u5236\u4e86NF-\u03baB\u548cMAPK\u7684\u6d3b\u5316[2]\u3002\u64da\u5831\u9053\uff0c\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u5177\u6709\u6297\u6c27\u5316\u4f5c\u7528\u3002\u4ee5\u4eba\u985e\u55dc\u9e7c\u6027\u7403\u682aKU812\u70ba\u7814\u7a76\u5c0d\u8c61\uff0c\u53e3\u670d\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u53ef\u6291\u5236\u7d44\u7e54\u80fa\u91cb\u653e\u53ca\u88ab\u52d5\u76ae\u819a\u53cd\u61c9[4]\u3002\u5728\u547c\u5438\u9053\u4e0a\u76ae\u7d30\u80deBEAS-2B\u4e2d\uff0c\u9ec3\u8006\u7532\u82f7\u6cbb\u7642\u53ef\u62ee\u6297\u5167\u6bd2\u7d20\u8a98\u5c0e\u7684\u6c27\u5316\u61c9\u6fc0\uff0c\u800c\u6c27\u5316\u58d3\u529b\u662f\u5c0e\u81f4\u547c\u5438\u9053\u529f\u80fd\u969c\u7919\u548c\u767c\u708e\u7684\u539f\u56e0[1]\u3002\u4ee5\u6c27\u5316\u72c0\u614b\u4e0b\u8a98\u5c0e\u7684\u4eba\u985e\u7d05\u8840\u7403\u70ba\u7814\u7a76\u5c0d\u8c61\uff0c\u53e3\u670d\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u53ef\u6291\u5236[3]\u3002\u5728NC\/Nga\u7570\u4f4d\u6027\u76ae\u819a\u708e\u5c0f\u9f20\u6a21\u578b\u4e2d\uff0c\u9ec3\u82aa\u9ec3\u916e(Astragalin)\u6cbb\u7642\u53ef\u986f\u8457\u6291\u5236\u76ae\u819a\u708e\u767c\u5c55\u3001\u6414\u6293\u884c\u70ba\u548c\u8840\u6e05IgE\u5347\u9ad8[4]\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Physical Appearance<\/td>\nA solid<\/td>\n<\/tr>\n
Storage<\/td>\nStore at -20\u00b0C<\/td>\n<\/tr>\n
M.Wt<\/td>\n448.38<\/td>\n<\/tr>\n
Cas No.<\/td>\n480-10-4<\/td>\n<\/tr>\n
Formula<\/td>\nC21<\/sub>H20<\/sub>O11<\/sub><\/td>\n<\/tr>\n
Solubility<\/td>\n\u226544.8 mg\/mL in DMSO; insoluble in H2O; insoluble in EtOH<\/td>\n<\/tr>\n
Chemical Name<\/td>\n5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one<\/td>\n<\/tr>\n
SDF<\/td>\nDownload SDF<\/a><\/td>\n<\/tr>\n
Canonical SMILES<\/td>\nC1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O<\/td>\n<\/tr>\n
Shipping Condition<\/td>\nSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n
General tips<\/td>\nWe do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
<\/div>\n
\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/div>\n
\n
\n

APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/p>\n<\/div>\n<\/div>\n

https:\/\/www.apexbt.com<\/a><\/span><\/p>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

\"\u578b\u9304\u4e0b\u8f09\"<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u5929\u7136\u7522\u54c1\u7cfb\u5217\u5546\u54c1->>\u9ec3\u82aa\u9ec3\u916e(Astragalin) APExBIO Technology LL […]<\/p>\n","protected":false},"author":3,"featured_media":47343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[6889],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/52019"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=52019"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/52019\/revisions"}],"predecessor-version":[{"id":53632,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/52019\/revisions\/53632"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/47343"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=52019"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=52019"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=52019"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}