{"id":50972,"date":"2025-04-16T18:17:25","date_gmt":"2025-04-16T10:17:25","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=50972"},"modified":"2025-08-12T11:25:17","modified_gmt":"2025-08-12T03:25:17","slug":"%e8%8f%b8%e9%b9%bc%e9%86%af%e8%83%ba-nicotinamide-cas98-92-0-mce%e8%b2%a8%e8%99%9fhy-b0150","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=50972","title":{"rendered":"\u83f8\u9e7c\u91af\u80fa (Nicotinamide)\u00a0 \u00a0| CAS#98-92-0 MCE\u8ca8\u865fHY-B0150\u00a0"},"content":{"rendered":"

MCE (MedChem Express)<\/span> -\u83f8\u9e7c\u91af\u80fa (Nicotinamide)<\/span><\/span><\/strong><\/span><\/p>\n

MCE\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\uff0c\u63d0\u4f9b\u7a2e\u985e\u9f4a\u5168\u7684\u5316\u5b78\u53ca\u751f\u5316\u7814\u7a76\u7528\u7522\u54c1\uff0c\u5305\u62ec\u5275\u65b0\u7684\u751f\u547d\u79d1\u5b78\u8a66\u5291\uff0creference compounds(\u6a19\u6e96\u5316\u5408\u7269)\uff0cAPIs(\u539f\u6599\u85e5)\u53caNatural compounds(\u5929\u7136\u5316\u5408\u7269)\u4ee5\u63d0\u4f9b\u5be6\u9a57\u5ba4\u6216\u79d1\u5b78\u7814\u7a76\u4e4b\u7528\uff0cMedChemExpress(MCE)\u7522\u54c150000+ \u7279\u7570\u6027\u6291\u5236\u5291\u3001\u5316\u5408\u7269\u5eab\u3001\u91cd\u7d44\u86cb\u767d\uff0c\u5c08\u6ce8\u65bc\u4fe1\u865f\u901a\u8def\u548c\u75be\u75c5\u7814\u7a76\u9818\u57df\u3002\u5168\u7403\u6587\u737b\u5ee3\u6cdb\u5f15\u7528\uff0c\u8cea\u63a7\u9ad4\u7cfb\u56b4\u683c\uff0c\u54c1\u8cea100%\u3002<\/p>\n

<\/p>\n

\u83f8\u9e7c\u91af\u80fa (Nicotinamide)\u00a0 \u00a0| CAS#98-92-0 MCE\u8ca8\u865fHY-B0150\u00a0<\/a><\/span><\/p>\n

Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits\u00a0SIRT2<\/a><\/b>\u00a0activity (IC50<\/sub><\/b>: 2 \u03bcM). Nicotinamide also inhibits\u00a0SIRT1<\/a>. Nicotinamide increases cellular NAD+<\/sub>, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV<\/a><\/b>\u00a0activity.
\n<\/p>\n

\u83f8\u9e7c\u91af\u80fa(Nicotinamide)\u662f\u7dad\u751f\u7d20 B3 \u6216\u83f8\u9e7c\u9178\u7684\u4e00\u7a2e\u5f62\u5f0f\u3002\u9e7d\u9178\u83f8\u9e7c\u91af\u80fa\u6291\u5236 SIRT2 \u6d3b\u6027\uff08IC50\uff1a2 \u03bcM\uff09\u3002\u83f8\u9e7c\u91af\u80fa(Nicotinamide) \u9084\u80fd\u6291\u5236 SIRT1\u3002\u83f8\u9e7c\u91af\u80fa(Nicotinamide) \u53ef\u589e\u52a0\u7d30\u80de NAD+\u3001ATP\u3001ROS \u6c34\u5e73\u3002\u83f8\u9e7c\u91af\u80fa(Nicotinamide) \u53ef\u6291\u5236\u816b\u7624\u751f\u9577\u4e26\u63d0\u9ad8\u5b58\u6d3b\u7387\u3002\u83f8\u9e7c\u91af\u80fa(Nicotinamide) \u9084\u5177\u6709\u6297B\u578b\u809d\u708e\u75c5\u6bd2\u6d3b\u6027\u3002<\/p>\n

<\/p>\n

<\/p>\n

<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Molecular Weight<\/th>\n\n
\n

122.12<\/p>\n<\/div>\n<\/td>\n<\/tr>\n

Formula<\/th>\n\n
\n

C6<\/sub>H6<\/sub>N2<\/sub>O<\/p>\n<\/div>\n<\/td>\n<\/tr>\n

CAS No.<\/th>\n\n
Appearance<\/th>\n\n
\n

Solid<\/p>\n<\/div>\n<\/td>\n<\/tr>\n

Color<\/th>\n\n
\n

White to off-white<\/p>\n<\/div>\n<\/td>\n<\/tr>\n

SMILES<\/th>\n\n
\n

O=C(C1=CC=CN=C1)N<\/p>\n<\/div>\n<\/td>\n<\/tr>\n

Structure Classification<\/th>\n\n
\n
Initial Source<\/th>\n\n
\n
Shipping<\/th>\n\n
\n

Room temperature in continental US; may vary elsewhere.<\/p>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a>\"\"<\/p>\n

MedChemexpress (MCE) \u7522\u54c1\u985e\u5225\uff0d\u4f9d\u7814\u7a76\u985e\u578b\u5340\u5206\uff1a<\/span><\/h4>\n

\u2022Anti-infection<\/a><\/span><\/strong><\/h4>\n

\u2022Antibody-drug Conjugate\/ADC Related<\/a><\/span><\/strong><\/h4>\n

\u2022Apoptosis<\/a><\/span><\/strong><\/h4>\n

\u2022Autophagy<\/a><\/span><\/strong><\/h4>\n

\u2022Cell Cycle\/DNA Damage<\/a><\/span><\/strong><\/h4>\n

\u2022Cytoskeleton<\/a><\/span><\/strong><\/h4>\n

\u2022Epigenetics<\/a><\/span><\/strong><\/h4>\n

\u2022GPCR\/G Protein<\/a><\/span><\/strong><\/h4>\n

\u2022Immunology\/Inflammation<\/a><\/span><\/strong><\/h4>\n

\u2022JAK\/STAT Signaling<\/a>\u2022MAPK\/ERK Pathway<\/a><\/span><\/strong><\/h4>\n

\u2022Membrane Transporter\/Ion Channel<\/a><\/span><\/strong><\/h4>\n

\u2022Metabolic Enzyme\/Protease<\/a><\/span><\/strong><\/h4>\n

\u2022Neuronal Signaling<\/a><\/span><\/strong><\/h4>\n

\u2022NF-\u03baB<\/a><\/span><\/strong><\/h4>\n

\u2022PI3K\/Akt\/mTOR<\/a><\/span><\/strong><\/h4>\n

\u2022PROTAC<\/a><\/span><\/strong><\/h4>\n

\u2022Protein Tyrosine Kinase\/RTK<\/a>\u2022Stem Cell\/Wnt<\/a><\/span><\/strong><\/h4>\n

\u2022TGF-beta\/Smad<\/a><\/span><\/strong><\/h4>\n

\u2022Vitamin D Related<\/a><\/span><\/strong><\/h4>\n

\u2022Others<\/a><\/span><\/strong><\/h4>\n","protected":false},"excerpt":{"rendered":"

MCE (MedChem Express) -\u83f8\u9e7c\u91af\u80fa (Nicotinamide) MCE\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f […]<\/p>\n","protected":false},"author":3,"featured_media":52323,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5369],"tags":[6867,6866,6869,6865,6868,6843],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50972"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=50972"}],"version-history":[{"count":4,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50972\/revisions"}],"predecessor-version":[{"id":52322,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50972\/revisions\/52322"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/52323"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=50972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=50972"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=50972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}