{"id":50737,"date":"2025-03-16T14:31:55","date_gmt":"2025-03-16T06:31:55","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=50737"},"modified":"2025-08-11T17:56:09","modified_gmt":"2025-08-11T09:56:09","slug":"mouse-igf-1-protein%e9%87%8d%e7%b5%84%e8%9b%8b%e7%99%bd-%e8%b2%a8%e8%99%9fprp1146","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=50737","title":{"rendered":"Mouse IGF-1 protein\u91cd\u7d44\u86cb\u767d | \u8ca8\u865fPRP1146"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/biopioneer.com.tw\/?p=50737&amp;preview=true\"><span style=\"color: #33cccc;\"><strong><span style=\"font-size: 12pt;\">Mouse IGF-1 protein\u91cd\u7d44\u86cb\u767d | \u8ca8\u865fPRP1146<\/span><\/strong><\/span><\/a><\/span><\/p>\n<p>Mouse IGF-1 protein<\/p>\n<p>\u80f0\u5cf6\u7d20\u6a23\u751f\u9577\u56e0\u5b50 1 (Insulin Like Growth Factors 1, IGF-I) \u662f\u985e\u80f0\u5cf6\u7d20\u751f\u9577\u56e0\u5b50\u7684 7.81 kDa \u6210\u54e1\uff0c\u5177\u6709 71 \u500b\u80fa\u57fa\u9178\u6b98\u57fa\u3002 IGF-I\u4e3b\u8981\u8868\u9054\u65bc\u809d\u81df( liver)\u3001\u8102\u80aa\u7d44\u7e54(adipose tissue)\u3001\u5b50\u5bae\u9838( cervi)\u3001\u5b50\u5bae\u5167\u819c\u9593\u8cea\u7d30\u80de(endometrial stromal cells)\u3001\u9593\u8cea\u7d30\u80de\uff0c\u4e26\u4e14\u53ef\u4ee5\u5f9e\u8840\u6f3f\u4e2d\u5206\u96e2\u3002 IGF-I \u4ecb\u5c0e\u86cb\u767d\u8cea\u5408\u6210\u4ee3\u8b1d\u548c\u4fc3\u9032\u8166\u4e0b\u5782\u9ad4\u751f\u9577\u6fc0\u7d20\u7684\u4f5c\u7528\u3002 IGF-I \u4e5f\u900f\u904e\u8207 IGF-I \u53d7\u9ad4\u7d50\u5408\u5f71\u97ff\u809d\u91a3\u4ee3\u8b1d\u3001DNA \u5408\u6210\u548c\u8461\u8404\u7cd6\u651d\u53d6( glucose uptake)\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2025\/03\/2-Mouse-IGF-1-protein%E9%87%8D%E7%B5%84%E8%9B%8B%E7%99%BD-%E8%B2%A8%E8%99%9FPRP1146.png\" \/><\/p>\n<p><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2025\/03\/1-Mouse-IGF-1-protein\u91cd\u7d44\u86cb\u767d-\u8ca8\u865fPRP1146.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/p>\n<table width=\"822\">\n<tbody>\n<tr>\n<td width=\"122\"><strong>Product name<\/strong><\/td>\n<td width=\"700\"><a href=\"https:\/\/www.abbkine.com\/product\/mouse-igf-1-protein-prp1146\/\">Mouse IGF-1 protein<\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Sequence<\/strong><\/td>\n<td width=\"700\">MGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKAA with polyhistidine tag at the C-terminus.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Activity<\/strong><\/td>\n<td width=\"700\">Measure by its ability to induce MCF-7 cells proliferation. The ED\u2085\u2080 for this effect is &lt;2 ng\/mL. The specific activity of recombinant mouse IGF-I is &gt; 5 x 10\u2075 IU\/mg.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Protein length<\/strong><\/td>\n<td width=\"700\">The protein has a calculated MW of 8.61 kDa. The protein migrates as 11-17 kDa under reducing condition (SDS-PAGE analysis).<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Preparation method<\/strong><\/td>\n<td width=\"700\">E. coli<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Purity<\/strong><\/td>\n<td width=\"700\">&gt;98% as determined by SDS-PAGE.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Alternative<\/strong><\/td>\n<td width=\"700\">Somatamedin C, IGF-IA<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Formulation<\/strong><\/td>\n<td width=\"700\">The protein was lyophilized from a 0.2 \u00b5m filtered solution containing 1X PBS, pH 8.0. If you have any concerns or special requirements, please confirm with us.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Features &amp; Benefits<\/strong><\/td>\n<td width=\"700\">Endotoxin:&lt;0.1 EU per 1 \u03bcg of the protein by the LAL method.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Molecular weight<\/strong><\/td>\n<td width=\"700\">The protein has a calculated MW of 8.61 kDa. The protein migrates as 11-17 kDa under reducing condition (SDS-PAGE analysis).<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Usage notes<\/strong><\/td>\n<td width=\"700\">Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H\u2082O to a concentration not less than 100 \u03bcg\/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Storage instructions<\/strong><\/td>\n<td width=\"700\">Lyophilized protein should be stored at -20\u00b0C for 1 year. Upon reconstitution,\u00a0 store at 2\u00b0C to 8\u00b0C for up to 1 week.\u00a0 Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose\u00a0 solution), protein aliquots should be stored at -20\u00b0C or -80\u00b0C for 3-6 months. Avoid repeated freeze\/thaw cycles.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Shipping<\/strong><\/td>\n<td width=\"700\">Gel pack with blue ice.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Precautions<\/strong><\/td>\n<td width=\"700\">The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Background<\/strong><\/td>\n<td width=\"700\">Insulin Like Growth Factors 1 (IGF-I) is a 7.81 kDa member of the Insulin-like Growth Factors with 71 amino acid residues. IGF-I is mainly expressed from liver, adipose tissue, cervi, endometrial stromal cells, leydig cells, and can be isolated from plasma. IGF-I is mediating the protein anabolic and promoting effect of pituitary growth hormone. IGF-I also affects metabolism of glycogen, DNA synthesis and glucose uptake via binding to IGF-I receptor.<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Alternative<\/strong><\/td>\n<td width=\"700\">Somatamedin C, IGF-IA<\/td>\n<\/tr>\n<tr>\n<td width=\"122\"><strong>Accession<\/strong><\/td>\n<td width=\"700\"><a href=\"https:\/\/www.abbkine.com\/product\/mouse-igf-1-protein-prp1146\/\">P05017<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mouse IGF-1 protein\u91cd\u7d44\u86cb\u767d | \u8ca8\u865fPRP1146 Mouse IGF-1 protein [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":29551,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5262],"tags":[6952],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50737"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=50737"}],"version-history":[{"count":4,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50737\/revisions"}],"predecessor-version":[{"id":53071,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50737\/revisions\/53071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/29551"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=50737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=50737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=50737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}