{"id":48573,"date":"2024-02-01T16:49:31","date_gmt":"2024-02-01T08:49:31","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=48573"},"modified":"2025-05-12T10:59:08","modified_gmt":"2025-05-12T02:59:08","slug":"dextran-sulfate-sodium-salt-mw36000-50000-cas9011-18-1-apexbio%e8%b2%a8%e8%99%9f-b8205","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=48573","title":{"rendered":"Dextran sulfate sodium salt (MW36000-50000) | CAS#9011-18-1 APExBIO\u8ca8\u865f B8205"},"content":{"rendered":"<p><span style=\"color: #993366;\"><strong><span style=\"font-size: 14pt;\"><span style=\"color: #ff9900;\"><span style=\"color: #800080;\">\u8a98\u767c\u75be\u75c5\u6a21\u578b\u7522\u54c1 (Induced Disease Models Products)-<span style=\"color: #ff9900;\">\u8461\u805a\u91a3\u786b\u9178\u9209\u9e7d\uff08Dextran sulfate sodium salt , DSS\uff09<\/span><\/span><\/span><\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2022\/09\/APExBIO_logo.jpg\" width=\"207\" height=\"42\" \/><\/p>\n<p>\u8461\u805a\u91a3\u786b\u9178\u9209\u9e7d(dextran sulfate sodium salt )\u5f62\u5f0f\u4f7f\u5176\u53ef\u6eb6\u65bc\u6c34\u4e14\u7a69\u5b9a\u3002\u786b\u9178\u8461\u805a\u91a3(Dextran sulfate )\u542b\u6709\u7d04 17% \u7684\u786b\uff0c\u76f8\u7576\u65bc\u6bcf\u500b\u8461\u8404\u7cd6\u6b98\u57fa\u7d04 2.3 \u500b\u786b\u9178\u57fa\u3002\u8461\u805a\u91a3\u786b\u9178\u9209\u9e7d\uff08Dextran sulfate sodium salt , DSS\uff09\u662f\u8461\u805a\u91a3(dextran)\u8207\u6c2f\u78fa\u9178\u916f\u5316\u800c\u6210\u7684\u805a\u9670\u96e2\u5b50\u884d\u751f\u7269 (polyanionic derivative)\u3002\u767c\u708e\u6027\u8178\u9053\u75be\u75c5\uff08Inflammatory bowel disease , IBD\uff09\u662f\u4e00\u7a2e\u6162\u6027( chronic)\u3001\u5fa9\u767c\u6027\u80c3\u8178\u9053\u611f\u67d3(relapsing gastrointestinal infection)\uff0c\u6703\u589e\u52a0\u8178\u9053\u816b\u7624(intestinal tumors)\u7684\u98a8\u96aa\u3002 1985\u5e74\uff0c\u9996\u6b21\u901a\u5831\u53f3\u65cb\u7cd6\u9150\u9209\u9e7d\uff08Dextran sulfate sodium salt, DSS\uff09\u53ef\u7528\u4f86\u5efa\u7acb\u5009\u9f20\u6f70\u760d\u6027\u7d50\u8178\u708e\u6a21\u578b\u3002\u5927\u91cf\u7814\u7a76\u8868\u660e\uff0cDSS\u7d50\u8178\u708e\u6a21\u578b\u8207\u4eba\u985e\u6f70\u760d\u6027\u7d50\u8178\u708e(ulcerative colitis)\u76f8\u4f3c\u3002\u900f\u904e\u6539\u8b8a\uff08Dextran sulfate sodium salt , DSS\uff09\u7684\u6fc3\u5ea6\u548c\u7d66\u85e5\u983b\u7387\u53ef\u4ee5\u8a98\u5c0e\u767c\u708e\u6027\u8178\u9053\u75be\u75c5\uff08Inflammatory bowel disease , IBD\uff09\u7684\u6025\u6027\u3001\u6162\u6027\u548c\u5fa9\u767c\u6a21\u578b\u3002\u8461\u805a\u91a3\u786b\u9178\u9209\u9e7d(dextran sulfate sodium salt )\u4e5f\u7528\u65bc\u5206\u5b50\u751f\u7269\u5b78\u61c9\u7528\uff0c\u5305\u62ec\u8102\u86cb\u767d\u6c89\u6fb1(lipoprotein precipitation)\u3001\u52a0\u901f DNA \u63a2\u91dd\u8207\u6838\u9178\u96dc\u4ea4\u4ee5\u53ca\u6838\u91a3\u9ad4\u5206\u96e2(ribosome separation)\u3002<\/p>\n<p><strong><span style=\"color: #33cccc;\"><a style=\"color: #33cccc;\" href=\"https:\/\/biopioneer.com.tw\/?p=48573&amp;preview=true\"><span style=\"font-size: 12pt;\">Dextran sulfate sodium salt (MW36000-50000) | CAS#9011-18-1 APExBIO\u8ca8\u865f B8205<\/span><\/a><\/span><\/strong><\/p>\n<p>SNucleic acid hybridization accelerant<\/p>\n<table>\n<tbody>\n<tr>\n<td>Physical Appearance<\/td>\n<td>A solid<\/td>\n<\/tr>\n<tr>\n<td>Storage<\/td>\n<td>Store at RT<\/td>\n<\/tr>\n<tr>\n<td>M.Wt<\/td>\n<td>36000-50000<\/td>\n<\/tr>\n<tr>\n<td>Cas No.<\/td>\n<td>9011-18-1<\/td>\n<\/tr>\n<tr>\n<td>Formula<\/td>\n<td>(C<sub>6<\/sub>H<sub>7<\/sub>Na<sub>3<\/sub>O<sub>14<\/sub>S<sub>3<\/sub>)n<\/td>\n<\/tr>\n<tr>\n<td>Solubility<\/td>\n<td>insoluble in EtOH; insoluble in DMSO; \u226555.5 mg\/mL in H2O<\/td>\n<\/tr>\n<tr>\n<td>Shipping Condition<\/td>\n<td>Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n<tr>\n<td>General tips<\/td>\n<td>We do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div class=\"detail-table \">\n<div class=\"detail-box-cont\">\n<p><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/02\/1-Dextran-sulfate-sodium-salt-MW36000-50000-CAS9011-18-1-APExBIO\u8ca8\u865f-B8205.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/p>\n<div class=\"detail-table \">\n<div class=\"detail-box-cont\">\n<ul id=\"artul\">\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37129719\" target=\"_blank\" rel=\"noopener\">1. Meng Guo, Rongrong Wang, et al. &#8220;Human TFF2-Fc fusion protein alleviates DSS-induced ulcerative colitis in C57BL\/6 mice by promoting intestinal epithelial cells repair and inhibiting\u00a0macrophage inflammation.&#8221; Inflammopharmacology. 2023 Jun;31(3):1387-1404. PMID: 37129719<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36778224\" target=\"_blank\" rel=\"noopener\">2. Chen L. &#8220;SCCA1\/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses.&#8221; bioRxiv 2023 Feb 03; PMID: 36778224<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36711606\" target=\"_blank\" rel=\"noopener\">3. Zheng W, Chang IC, et al. &#8220;Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during persistent infection.&#8221; bioRxiv 2023 Jan 20 PMID: 36711606<\/a><\/li>\n<li><a href=\"https:\/\/doi.org\/10.1101\/2023.01.12.523780\" target=\"_blank\" rel=\"noopener\">4. Alastair Copland, Gillian M. Mackie, et al. &#8220;Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity.&#8221; bioRxiv. January 13, 2023<\/a><\/li>\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35174751\" target=\"_blank\" rel=\"noopener\">5. Han Li, Bo Pang, et al. &#8220;Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis.&#8221; Immunopharmacol Immunotoxicol. 2022 Apr;44(2):238-246. PMID: 35174751<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2022\/09\/APExBIO_logo.jpg\" width=\"370\" height=\"105\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\"><a style=\"color: #800000;\" href=\"http:\/\/www.apexbt.com\/\">APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/span><\/p>\n<p><span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.apexbt.com\">https:\/\/www.apexbt.com<\/a><\/span><\/p>\n<p>APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8a98\u767c\u75be\u75c5\u6a21\u578b\u7522\u54c1 (Induced Disease Models Products)-\u8461\u805a\u91a3\u786b\u9178\u9209\u9e7d\uff08Dext [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":47343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[6550],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48573"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48573"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48573\/revisions"}],"predecessor-version":[{"id":51198,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48573\/revisions\/51198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/47343"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48573"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=48573"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=48573"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}