{"id":47711,"date":"2023-12-07T18:05:32","date_gmt":"2023-12-07T10:05:32","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=47711"},"modified":"2025-11-15T13:35:01","modified_gmt":"2025-11-15T05:35:01","slug":"%e7%99%bd%e8%97%9c%e8%98%86%e9%86%87-resveratrol-cas501-36-0-apexbio%e8%b2%a8%e8%99%9f-a4182","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=47711","title":{"rendered":"\u767d\u85dc\u8606\u9187 (Resveratrol)| CAS#501-36-0 APExBIO\u8ca8\u865f A4182"},"content":{"rendered":"<p><span style=\"color: #993366;\"><strong><span style=\"font-size: 14pt;\"><span style=\"color: #ff9900;\"><span style=\"color: #800080;\">\u5929\u7136\u591a\u915a\u690d\u7269\u6297\u6bd2\u7d20(polyphenolic phytoalexin)-<span style=\"color: #ff9900;\">\u767d\u85dc\u8606\u9187 (Resveratrol)<\/span><br \/>\n<\/span><\/span><\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2022\/09\/APExBIO_logo.jpg\" width=\"207\" height=\"42\" \/><\/p>\n<p>\u767d\u85dc\u8606\u9187(Resveratrol)\u662f\u4e00\u7a2e\u6700\u521d\u5f9e\u85dc\u8606(Veratrum grandiflorum)\u4e2d\u5206\u96e2\u51fa\u4f86\u7684\u915a\u985e\u7269\u8cea\uff0c\u5bcc\u542b\u65bc\u8461\u8404( grapes)\u3001\u8461\u8404\u9152(wine)\u3001\u82b1\u751f\u3001\u5927\u8c46( soy)\u548c\u6f3f\u679c(berries)\u4e2d\uff0c\u5e7e\u5341\u5e74\u4f86\u4e00\u76f4\u5438\u5f15\u8457\u79d1\u5b78\u5bb6\u548c\u91ab\u751f\u7684\u6ce8\u610f\u3002\u8a31\u591a\u7814\u7a76\u5831\u544a\u9053\u767d\u85dc\u8606\u9187\u5177\u6709\u591a\u7a2e\u751f\u7269\u6d3b\u6027\uff0c\u5982\u6297\u6c27\u5316(antioxidant)\u3001\u6297\u767c\u708e(anti-inflammatory)\u3001\u5fc3\u8840\u7ba1\u4fdd\u8b77(cardiovascular protection)\u3001\u6297\u764c(anticancer)\u3001\u6297\u7cd6\u5c3f\u75c5(antidiabetes)\u3001\u6297\u80a5\u80d6(antiobesity)\u3001\u795e\u7d93\u4fdd\u8b77(neuroprotection)\u548c\u6297\u8870\u8001( antiaging effects)\u7b49\u4f5c\u7528\u3002<a href=\"https:\/\/biopioneer.com.tw\/?news=apexbio%e5%8f%b0%e7%81%a3%e4%bb%a3%e7%90%86%e5%95%86-brandagency%e4%bb%a3%e7%90%86%e5%93%81%e7%89%8c-apexbio-2\"><span style=\"color: #ff0000;\"><em><strong><span style=\"text-decoration: underline;\">&gt;&gt;\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n<p><strong><span style=\"color: #33cccc;\"><a style=\"color: #33cccc;\" href=\"https:\/\/biopioneer.com.tw\/?p=47585&amp;preview=true\"><span style=\"font-size: 12pt;\">\u767d\u85dc\u8606\u9187 (Resveratrol)| CAS#501-36-0 APExBIO\u8ca8\u865f A4182<\/span><\/a><\/span><\/strong><\/p>\n<p>SIRT1 activator Purity: 99.94%<\/p>\n<p>\u767d\u85dc\u8606\u9187 (Resveratrol) \u6a19\u6e96\u54c1\u7528\u65bc\u7814\u7a76\u548c\u5206\u6790\u61c9\u7528\u3002\u767d\u85dc\u8606\u9187(Resveratrol)\uff08\u53cd\u5f0f\u767d\u85dc\u8606\u9187\uff1bSRT501\uff09\u662f\u4e00\u7a2e\u5929\u7136\u591a\u915a\u690d\u7269\u6297\u6bd2\u7d20(polyphenolic phytoalexin)\uff0c\u5177\u6709\u6297\u6c27\u5316(anti-oxidant)\u3001\u6297\u767c\u708e(anti-inflammatory)\u3001\u5fc3\u81df\u4fdd\u8b77(cardioprotective)\u548c\u6297\u764c\u7279\u6027(anti-cancer properties)\u3002\u767d\u85dc\u8606\u9187(SRT 501) \u5177\u6709\u5ee3\u6cdb\u7684\u76ee\u6a19\uff0c\u5305\u62ecmTOR\u3001 JAK\u3001 \u03b2-\u6fb1\u7c89\u6a23\u86cb\u767d(\u03b2-amyloid)\u3001\u817a\u82f7\u9178\u74b0\u5316\u9176(Adenylyl cyclase)\u3001 IKK\u03b2\u3001 DNA \u805a\u5408\u9176(DNA polymerase)\u3002\u767d\u85dc\u8606\u9187(Resveratrol)\u4e5f\u662f\u4e00\u7a2e\u7279\u6b8a\u7684SIRT1\u6fc0\u6d3b\u5291\u3002\u767d\u85dc\u8606\u9187(Resveratrol)\u662f\u4e00\u7a2e\u6709\u6548\u7684\u5b55\u70f7 X \u53d7\u9ad4 ( potent pregnane X receptor PXR) \u6291\u5236\u5291\u3002\u767d\u85dc\u8606\u9187\u662f\u4e00\u7a2eNrf2\u6d3b\u5316\u5291\uff0c\u53ef\u6539\u5584\u5c0f\u9f20\u6a21\u578b\u4e2d\u8207\u8001\u5316\u76f8\u95dc\u7684\u9032\u884c\u6027\u814e\u640d\u50b7\u3002\u767d\u85dc\u8606\u9187(Resveratrol)\u53ef\u589e\u52a0\u5167\u76ae\u7d30\u80de\u4e2d NO \u7684\u7522\u751f\u3002<\/p>\n<p>\u5728\u521d\u4ee3\u795e\u7d93\u5143\u57f9\u990a\u7269\u4e2d\uff0c\u767d\u85dc\u8606\u9187 (Resveratrol) \uff080.1\u30011 \u548c10 \u03bcM\uff09\u53ef\u6291\u5236OGD\/\u518d\u704c\u6ce8\u8a98\u5c0e\u7684\u7d30\u80de\u51cb\u4ea1(reperfusion-induced apoptosis)\uff0c\u4e26\u4ee5\u6fc3\u5ea6\u4f9d\u8cf4\u6027\u65b9\u5f0f\u6291\u5236caspase-3 \u548ccaspase-12 mRNA \u7684\u904e\u5ea6\u8868\u9054\u3002\u5728\u795e\u7d93\u6bcd\u7d30\u80de\u7624 SH-SY5Y \u7d30\u80de\u682a\u4e2d\uff0c\u767d\u85dc\u8606\u9187 (50 \u03bcM) \u900f\u904e\u6539\u5584\u7d30\u80de\u5167\u6c27\u5316\u58d3\u529b( oxidative stress )\u548c\u589e\u52a0\u4fc3\u5b58\u6d3b\u57fa\u56e0 Bcl-2 (prosurvival gene Bcl-2)\u7684\u6d3b\u6027\u4f86\u6291\u5236\u904e\u91cf\u591a\u5df4\u80fa(dopamine-induced cell death )\u8a98\u5c0e\u7684\u7d30\u80de\u6b7b\u4ea1\u3002\u5728\u906d\u53d7\u5fc3\u808c\u7f3a\u8840(myocardial ischemia)\u7684\u5927\u9f20\u4e2d\uff0c\u767d\u85dc\u8606\u9187 (Resveratrol)\uff082.5\u30015.0 mg\/kg\uff09\u900f\u904e\u6539\u5584\u7f3a\u8840\u5f8c\u5fc3\u5ba4\u6062\u5fa9\u3001\u6e1b\u5c11\u5fc3\u808c\u6897\u585e\u9762\u7a4d(myocardial infarct size)\u548c\u5fc3\u808c\u7d30\u80de\u51cb\u4ea1\u4f86\u8868\u73fe\u51fa\u5fc3\u81df\u4fdd\u8b77\u4f5c\u7528\u3002\u7136\u800c\uff0c25 \u6216 50 mg\/kg \u5291\u91cf\u7684\u767d\u85dc\u8606\u9187\u6703\u6291\u5236\u5fc3\u81df\u529f\u80fd\uff0c\u4e26\u589e\u52a0\u5fc3\u808c\u6897\u585e\u9762\u7a4d(myocardial infarct size)\u548c\u51cb\u4ea1\u7d30\u80de\u6578\u91cf\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/2-%E7%99%BD%E8%97%9C%E8%98%86%E9%86%87-Resveratrol-CAS501-36-0-MCE%E8%B2%A8%E8%99%9FHY-16561R.gif\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/3-%E7%99%BD%E8%97%9C%E8%98%86%E9%86%87-ResveratrolCAS501-36-0-APExBIO%E8%B2%A8%E8%99%9F-A4182.jpg\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/4-%E7%99%BD%E8%97%9C%E8%98%86%E9%86%87-ResveratrolCAS501-36-0-APExBIO%E8%B2%A8%E8%99%9F-A4182.jpg\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/5-%E7%99%BD%E8%97%9C%E8%98%86%E9%86%87-ResveratrolCAS501-36-0-APExBIO%E8%B2%A8%E8%99%9F-A4182.jpg\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/6-%E7%99%BD%E8%97%9C%E8%98%86%E9%86%87-ResveratrolCAS501-36-0-APExBIO%E8%B2%A8%E8%99%9F-A4182.jpg\" \/><\/p>\n<div id=\"cite\" class=\"tbar\">\n<h2><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\">Product Citation<\/span><\/strong><\/span><\/h2>\n<\/div>\n<div class=\"detail-table \">\n<div class=\"detail-box-cont\">\n<ul id=\"artul\">\n<li><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36137422\" target=\"_blank\" rel=\"noopener\">1. Xin Chou, Xiaohu Li, et al. &#8220;Sirtuin-1 attenuates cadmium-induced renal cell senescence through p53 deacetylation.&#8221; Ecotoxicol Environ Saf. 2022 Oct 15;245:114098. PMID: 36137422<\/a><\/li>\n<li><a>2. Li Y, Xi Y, et al. &#8220;Sirtuin 1 activation alleviates primary biliary cholangitis via the blocking of the NF-\u03baB signaling pathway.&#8221;\u00a0Int Immunopharmacol. 2020;83:106386.<\/a>\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32193100\" target=\"_blank\" rel=\"noopener\">PMID: 32193100<\/a><\/li>\n<li><a>3. Song Y, Chen Y, et al. &#8220;Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling.&#8221; Biomed Res Int. 2019 Apr 7;2019:1321973.<\/a>\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31119150\" target=\"_blank\" rel=\"noopener\">PMID: 31119150<\/a><\/li>\n<li><a>4. Chou X, Ding F, et al. &#8220;Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells.&#8221; Arch Toxicol. 2019 Feb 22.<\/a>\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30796460\" target=\"_blank\" rel=\"noopener\">PMID: 30796460<\/a><\/li>\n<\/ul>\n<table>\n<tbody>\n<tr>\n<td>Physical Appearance<\/td>\n<td>A solid<\/td>\n<\/tr>\n<tr>\n<td>Storage<\/td>\n<td>Store at -20\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>M.Wt<\/td>\n<td>228.24<\/td>\n<\/tr>\n<tr>\n<td>Cas No.<\/td>\n<td>501-36-0<\/td>\n<\/tr>\n<tr>\n<td>Formula<\/td>\n<td>C<sub>14<\/sub>H<sub>12<\/sub>O<sub>3<\/sub><\/td>\n<\/tr>\n<tr>\n<td>Solubility<\/td>\n<td>insoluble in H2O; \u226548.2 mg\/mL in EtOH with ultrasonic; \u22659.65 mg\/mL in DMSO<\/td>\n<\/tr>\n<tr>\n<td>Chemical Name<\/td>\n<td>5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol<\/td>\n<\/tr>\n<tr>\n<td>SDF<\/td>\n<td><a href=\"https:\/\/www.apexbt.com\/downloader\/sdf\/A4182.sdf\">Download SDF<\/a><\/td>\n<\/tr>\n<tr>\n<td>Canonical SMILES<\/td>\n<td>C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O<\/td>\n<\/tr>\n<tr>\n<td>Shipping Condition<\/td>\n<td>Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n<tr>\n<td>General tips<\/td>\n<td>We do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/12\/1\u767d\u85dc\u8606\u9187-ResveratrolCAS501-36-0-APExBIO\u8ca8\u865f-A4182.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/p>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2022\/09\/APExBIO_logo.jpg\" width=\"370\" height=\"105\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #800000;\"><strong><span style=\"font-size: 12pt;\"><a style=\"color: #800000;\" href=\"http:\/\/www.apexbt.com\/\">APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/span><\/p>\n<p><span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"https:\/\/www.apexbt.com\">https:\/\/www.apexbt.com<\/a><\/span><\/p>\n<p>APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<a href=\"https:\/\/biopioneer.com.tw\/?news=apexbio%e5%8f%b0%e7%81%a3%e4%bb%a3%e7%90%86%e5%95%86-brandagency%e4%bb%a3%e7%90%86%e5%93%81%e7%89%8c-apexbio-2\"><span style=\"color: #ff0000;\"><em><strong><span style=\"text-decoration: underline;\">&gt;&gt;\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n<table width=\"725\">\n<tbody>\n<tr>\n<td width=\"68\">Catalog<\/td>\n<td width=\"100\">Sku<\/td>\n<td width=\"162\">Name<\/td>\n<td width=\"120\">CAS<\/td>\n<td width=\"275\">Short Summary<\/td>\n<\/tr>\n<tr>\n<td>A3821<\/td>\n<td>A3821-5<\/td>\n<td>SRT2104 (GSK2245840)<\/td>\n<td>1093403-33-8<\/td>\n<td>SIRT1 activator,selective<\/td>\n<\/tr>\n<tr>\n<td>A3839<\/td>\n<td>A3839-50<\/td>\n<td>SRT3190<\/td>\n<td>1204707-73-2<\/td>\n<td>CXCR2 ligand,SIRT1 activator<\/td>\n<\/tr>\n<tr>\n<td>A4180<\/td>\n<td>A4180-5<\/td>\n<td>SRT1720 HCl<\/td>\n<td>1001645-58-4<\/td>\n<td>SIRT1 activator<\/td>\n<\/tr>\n<tr>\n<td>A4182<\/td>\n<td>A4182-5.1<\/td>\n<td>Resveratrol<\/td>\n<td>501-36-0<\/td>\n<td>SIRT1 activator<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5929\u7136\u591a\u915a\u690d\u7269\u6297\u6bd2\u7d20(polyphenolic phytoalexin)-\u767d\u85dc\u8606\u9187 (Resveratrol)  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":47343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[6867,6866,6869,6865,6868,6432],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/47711"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=47711"}],"version-history":[{"count":7,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/47711\/revisions"}],"predecessor-version":[{"id":53633,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/47711\/revisions\/53633"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/47343"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=47711"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=47711"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=47711"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}