{"id":45923,"date":"2023-10-04T11:19:35","date_gmt":"2023-10-04T03:19:35","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=45923"},"modified":"2023-11-24T16:01:36","modified_gmt":"2023-11-24T08:01:36","slug":"polyic-toll-like-receptor-3-tlr3-agonist-cas24939-03-5-apexbio%e8%b2%a8%e8%99%9fb5551","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=45923","title":{"rendered":"Poly(I:C) Toll-like receptor 3 (TLR3) agonist CAS#24939-03-5 APExBIO\u8ca8\u865fB5551"},"content":{"rendered":"

Poly(I:C) Toll-like receptor 3 (TLR3) agonist CAS#24939-03-5 APExBIO\u8ca8\u865fB5551<\/span><\/a><\/span><\/strong><\/p>\n

Poly(I:C) Toll-like receptor 3 (TLR3) agonist
\n\u7522\u54c1\u4ecb\u7d39 <\/span><\/strong><\/span>Poly (I:C) \u662f\u4e00\u7a2e\u5408\u6210\u7684\u96d9\u80a1 RNA (dsRNA) \u985e\u4f3c\u7269\uff0c\u662f\u4e00\u7a2e\u514d\u75ab\u523a\u6fc0\u5291\uff0c\u53ef\u4f5c\u70ba\u6700\u6709\u6548\u7684\u5e72\u64fe\u7d20 (interferon, IFN) \u8a98\u5c0e\u5291\u3002 Toll \u6a23\u53d7\u9ad4 3 (TLR3) \u6fc0\u52d5\u5291(agonist)[1]\u3002\u5176\u5e73\u5747\u5206\u5b50\u91cf\u57281.5-8kb\u4e4b\u9593\u3002\u542b\u6709 TLR7\/8 \u6fc0\u52d5\u5291 R848 \u6216 CL075 \u7684\u6df7\u5408\u7269\u8207 Poly (I:C) \u7d50\u5408\uff0c\u7522\u751f 3 \u5929\u6210\u719f\u7684\u6a39\u7a81\u7d30\u80de [2]\u3002\u901a\u5e38\u7528\u65bc\u523a\u6fc0\u9ad4\u5167\u514d\u75ab\u7cfb\u7d71\u7684\u6d3b\u5316\u3002\u4e5f\u4fc3\u9032 hPSC \u4f86\u6e90\u7684\u5fc3\u808c\u7d30\u80de\u7684\u6210\u719f[3]\u3002<\/p>\n\n\n\n\n\n\n\n\n\n
Physical Appearance<\/td>\nA solid (HMW)<\/td>\n<\/tr>\n
Storage<\/td>\nStore at -20\u00b0C<\/td>\n<\/tr>\n
Cas No.<\/td>\n24939-03-5<\/td>\n<\/tr>\n
Formula<\/td>\n(C10<\/sub>H13<\/sub>N4<\/sub>O8<\/sub>P)x.(C9<\/sub>H14<\/sub>N3<\/sub>O8<\/sub>P)x<\/td>\n<\/tr>\n
Solubility<\/td>\ninsoluble in DMSO; insoluble in EtOH; \u226521.5 mg\/mL in H2O<\/td>\n<\/tr>\n
Shipping Condition<\/td>\nSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n
General tips<\/td>\nFor obtaining a higher solubility, please warm the tube at 37\u00b0C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n

<\/p>\n

APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/span><\/p>\n

https:\/\/www.apexbt.com<\/a><\/span><\/p>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

Poly(I:C) Toll-like receptor 3 (TLR3) agonist CAS#24939 […]<\/p>\n","protected":false},"author":3,"featured_media":47343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[6125],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45923"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=45923"}],"version-history":[{"count":2,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45923\/revisions"}],"predecessor-version":[{"id":45925,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45923\/revisions\/45925"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/47343"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=45923"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=45923"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=45923"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}