{"id":41527,"date":"2023-04-23T14:03:23","date_gmt":"2023-04-23T06:03:23","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=41527"},"modified":"2023-04-23T14:14:39","modified_gmt":"2023-04-23T06:14:39","slug":"egta-calcium-chelator-cas67-42-5-apexbio%e8%b2%a8%e8%99%9fb7195","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=41527","title":{"rendered":"EGTA| Calcium chelator CAS#67-42-5 APExBIO\u8ca8\u865fB7195"},"content":{"rendered":"

EGTA| Calcium chelator CAS#67-42-5 APExBIO\u8ca8\u865fB7195<\/strong><\/span><\/a><\/span><\/p>\n

EGTA, also known as egtazic acid, is an aminopolycarboxylic acid, a calcium chelator. It can protects against cell death caused by nitric oxide-induced calcium influx into nerve cells[1,2].<\/p>\n

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EGTA\u7522\u54c1\u4ecb\u7d39<\/span><\/strong><\/span><\/p>\n

EGTA, also known as egtazic acid, is an aminopolycarboxylic acid, a calcium chelator. It can protects against cell death caused by nitric oxide-induced calcium influx into nerve cells[1,2]. EGTA\uff0c\u53c8\u7a31egtazic acid\uff0c\u662f\u4e00\u7a2e\u6c28\u57fa\u591a\u7fa7\u9178(aminopolycarboxylic acid)\uff0c\u662f\u4e00\u7a2e\u9223\u87af\u5408\u5291(calcium chelator)\u3002\u5b83\u53ef\u4ee5\u9632\u6b62\u56e0\u4e00\u6c27\u5316\u6c2e\u8a98\u5c0e(nitric oxide-induced )\u7684\u9223\u6d41(calcium influx )\u5165\u795e\u7d93\u7d30\u80de\u800c\u5f15\u8d77\u7684\u7d30\u80de\u6b7b\u4ea1(cell death)\u3002<\/p>\n

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EGTA-<\/span><\/strong>Product Citation<\/span><\/h2>\n<\/div>\n
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1. Yu Q, Wang D, et al. “Adipose-derived Exosomes Protect the Pulmonary Endothelial Barrier in Ventilator-induced Lung Injury by Inhibiting the TRPV4\/Ca2+ Signaling Pathway.” Am J Physiol Lung Cell Mol Physiol. 2020;10.1152\/ajplung.00255.2019.<\/a>\u00a0PMID:32073873<\/a><\/p>\n<\/div>\n<\/div>\n

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EGTA-Chemical Properties<\/span><\/strong><\/span><\/h2>\n<\/div>\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Physical Appearance<\/td>\nA solid<\/td>\n<\/tr>\n
Storage<\/td>\nStore at RT<\/td>\n<\/tr>\n
M.Wt<\/td>\n380.35<\/td>\n<\/tr>\n
Cas No.<\/td>\n67-42-5<\/td>\n<\/tr>\n
Formula<\/td>\nC14<\/sub>H24<\/sub>N2<\/sub>O10<\/sub><\/td>\n<\/tr>\n
Solubility<\/td>\ninsoluble in H2O; insoluble in DMSO; insoluble in EtOH<\/td>\n<\/tr>\n
Chemical Name<\/td>\n3,12-bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid<\/td>\n<\/tr>\n
SDF<\/td>\nDownload SDF<\/a><\/td>\n<\/tr>\n
Canonical SMILES<\/td>\nOC(CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O)=O<\/td>\n<\/tr>\n
Shipping Condition<\/td>\nSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n
General tips<\/td>\nFor obtaining a higher solubility, please warm the tube at 37\u00b0C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\"COA\u6587\u4ef6_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n

APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/strong><\/span><\/p>\n

https:\/\/www.apexbt.com<\/a><\/span><\/p>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

EGTA| Calcium chelator CAS#67-42-5 APExBIO\u8ca8\u865fB7195 EGTA, […]<\/p>\n","protected":false},"author":3,"featured_media":34299,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[5614],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/41527"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=41527"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/41527\/revisions"}],"predecessor-version":[{"id":41530,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/41527\/revisions\/41530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/34299"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=41527"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=41527"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=41527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}