{"id":39803,"date":"2023-03-10T15:35:58","date_gmt":"2023-03-10T07:35:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=39803"},"modified":"2025-09-03T19:15:54","modified_gmt":"2025-09-03T11:15:54","slug":"atezolizumab-cas1380723-44-3-medchemexpressmce%e8%b2%a8%e8%99%9fhy-p9904","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=39803","title":{"rendered":"Atezolizumab | CAS#1380723-44-3 MedChemExpress(MCE)\u8ca8\u865fHY-P9904"},"content":{"rendered":"

MCE (MedChem Express)<\/span> Atezolizumab<\/span><\/span><\/strong><\/span><\/p>\n

MCE\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\uff0c\u63d0\u4f9b\u7a2e\u985e\u9f4a\u5168\u7684\u5316\u5b78\u53ca\u751f\u5316\u7814\u7a76\u7528\u7522\u54c1\uff0c\u5305\u62ec\u5275\u65b0\u7684\u751f\u547d\u79d1\u5b78\u8a66\u5291\uff0creference compounds(\u6a19\u6e96\u5316\u5408\u7269)\uff0cAPIs(\u539f\u6599\u85e5)\u53caNatural compounds(\u5929\u7136\u5316\u5408\u7269)\u4ee5\u63d0\u4f9b\u5be6\u9a57\u5ba4\u6216\u79d1\u5b78\u7814\u7a76\u4e4b\u7528\uff0cMedChemExpress(MCE)\u7522\u54c150000+ \u7279\u7570\u6027\u6291\u5236\u5291\u3001\u5316\u5408\u7269\u5eab\u3001\u91cd\u7d44\u86cb\u767d\uff0c\u5c08\u6ce8\u65bc\u4fe1\u865f\u901a\u8def\u548c\u75be\u75c5\u7814\u7a76\u9818\u57df\u3002\u5168\u7403\u6587\u737b\u5ee3\u6cdb\u5f15\u7528\uff0c\u8cea\u63a7\u9ad4\u7cfb\u56b4\u683c\uff0c\u54c1\u8cea100%<\/p>\n

<\/p>\n

Atezolizumab\u00a0| CAS#1380723-44-3 MedChemExpress(MCE)\u8ca8\u865fHY-P9904\u00a0<\/a><\/span>
\nAtezolizumab (MPDL3280A) \u662f\u4e00\u7a2e\u91dd\u5c0d\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u914d\u9ad4 1 (programmed death ligand 1 , PD-L1) \u7684\u9078\u64c7\u6027\u4eba\u6e90\u5316\u55ae\u514b\u9686 IgG1 \u6297\u9ad4(humanized monoclonal IgG1 antibody )\uff0c\u7528\u65bc\u764c\u75c7\u7814\u7a76(\u00a0cancer research)\u3002Atezolizumab\uff080\u30012.5\u30015\u300110\u300120 \u548c 40\u03bcg\/ml\uff1b24 \u5c0f\u6642\uff1bHOS \u548c 143B \u7d30\u80de\uff09\u6291\u5236\u589e\u6b96\u4e26\u8a98\u5c0e\u9aa8\u8089\u7624\u7d30\u80de\u7684\u514d\u75ab\u975e\u4f9d\u8cf4\u6027\u7d30\u80de\u51cb\u4ea1[1]\u3002Atezolizumab \u640d\u5bb3\u7dda\u7c92\u9ad4(\u00a0mitochondria)\u7684\u529f\u80fd\uff0c\u5c0e\u81f4\u6c27\u5316\u5291(oxidants)\u548c\u6297\u6c27\u5316\u5291(antioxidants)\u4e4b\u9593\u7684\u5931\u8861\u3002 Atezolizumab \u901a\u904e\u6fc0\u6d3b JNK \u8def\u5f91 (JNK pathway) \u8a98\u5c0e\u9aa8\u8089\u7624\u7d30\u80de(osteosarcoma cells)\u7dda\u7c92\u9ad4\u76f8\u95dc\u7684\u51cb\u4ea1(mitochondria-related apoptosis )\u3002 Atezolizumab\uff0810\u00b5g\/ml\uff1b24 \u5c0f\u6642\uff1bHOS \u548c 143B \u7d30\u80de\uff09\u8a98\u5c0e\u9aa8\u8089\u7624\u7d30\u80de(osteosarcoma cells)\u81ea\u566c(autophagy)[1]\u3002<\/p>\n

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Atezolizumab<\/strong>\u00a0purchased from MCE. Usage Cited in:\u00a0EJNMMI Res<\/cite>. 2020 Jun 15;10(1):64. \u00a0<\/a>[Abstract]<\/b><\/a><\/span><\/p>\n

Western blot analysis of total cell lysates using anti-PD-L1 (Atezolizumab, 6.91\u2009nM) and anti-\u03b2-actin antibody between LoVo, LS174T, SW620, and RKO in vitro.<\/p>\n

<\/p>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n

\"\"<\/p>\n

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MedChemexpress (MCE) \u7522\u54c1<\/span><\/h4>\n

MCE (MedChemexpress) \u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\uff0c\u63d0\u4f9b\u7a2e\u985e\u9f4a\u5168\u7684\u5316\u5b78\u53ca\u751f\u5316\u7814\u7a76\u7528\u7522\u54c1\uff0c\u5305\u62ec\u5275\u65b0\u7684\u751f\u547d\u79d1\u5b78\u8a66\u5291\uff0creference compounds (\u6a19\u6e96\u5316\u5408\u7269)\uff0cAPIs (\u539f\u6599\u85e5) \u53caNatural compounds (\u5929\u7136\u5316\u5408\u7269)\u4ee5\u63d0\u4f9b\u5be6\u9a57\u5ba4\u6216\u79d1\u5b78\u7814\u7a76\u4e4b\u7528\uff0cMedChemExpress(MCE)\u7522\u54c150000+ \u7279\u7570\u6027\u6291\u5236\u5291\u3001\u5316\u5408\u7269\u5eab\u3001\u91cd\u7d44\u86cb\u767d\uff0c\u5c08\u6ce8\u65bc\u4fe1\u865f\u901a\u8def\u548c\u75be\u75c5\u7814\u7a76\u9818\u57df\u3002\u5168\u7403\u6587\u737b\u5ee3\u6cdb\u5f15\u7528\uff0c\u8cea\u63a7\u9ad4\u7cfb\u56b4\u683c\uff0c\u54c1\u8cea100%\u3002\u5b98\u7db2\u9023\u7d50<\/span> https:\/\/www.medchemexpress.com<\/a><\/span><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5316\u5408\u7269\u54c1\u724c<\/td>\n\u5316\u5408\u7269CAS\u865f<\/td>\n\u5316\u5408\u7269\u540d\u7a31<\/td>\n\u5316\u5408\u7269\u8ca8\u865f<\/td>\n\u5316\u5408\u7269\u4ecb\u7d39<\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#108321-42-2<\/td>\nG-418 disulfat<\/td>\nMCE\u8ca8\u865fHY-17561<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#68528-80-3<\/td>\nDSS Crosslinker (disuccinimidyl suberate)<\/td>\nMCE\u8ca8\u865fHY-W019543<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#1380723-44-3<\/td>\nAtezolizumab<\/td>\nMCE\u8ca8\u865fHY-P9904<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#1207456-01-6<\/td>\nTalazoparib (BMN-673; LT-673)<\/td>\nMCE\u8ca8\u865fHY-16106<\/span><\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#763113-22-0<\/td>\nOlaparib<\/td>\nMCE\u8ca8\u865fHY-10162<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#1382764-52-4<\/td>\nLipidGreen 2\u8102\u8cea\u6210\u50cf\u5c0f\u5206\u5b50\u63a2\u91dd<\/td>\nMCE\u8ca8\u865fHY-D1353<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#103404-75-7<\/td>\nD-\u87a2\u5149\u7d20(D-luciferin) \u6c34\u6eb6\u6027\u9209\u9e7d<\/td>\nMCE\u8ca8\u865fHY-12591<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#15144-35-9<\/td>\nD-\u87a2\u5149\u7d20(D-Luciferin potassium)<\/td>\nMCE\u8ca8\u865fHY-12591B<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#186689-07-6<\/td>\n2-NBDG\u6d3b\u7d30\u80de\u548c\u7d44\u7e54\u8461\u8404\u7cd6\u7684\u651d\u53d6<\/td>\nMCE\u8ca8\u865fHY-116215<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\n<\/td>\nIPTG\u00a0 ( Isopropyl \u03b2-D-thiogalactoside)<\/td>\nMCE\u8ca8\u865fHY-15921<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#10121-91-2<\/td>\n\u81ea\u566c\u6ce1(autophagic vacuoles)\u87a2\u5149\u6a19\u8a8c<\/td>\nMCE\u8ca8\u865fHY-D1027<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#28728-55-4<\/td>\n\u805a\u51dd\u80fa(Polybrene) \u967d\u96e2\u5b50\u805a\u5408\u7269<\/td>\nMCE\u8ca8\u865fHY-112735<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#288250-47-5<\/td>\nY-320 \u514d\u75ab\u8abf\u7bc0\u5291<\/td>\nMCE\u8ca8\u865fHY-15898<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#30931-67-0<\/td>\nABTS diammonium salt<\/td>\nMCE\u8ca8\u865fHY-15902<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#16561-29-8<\/td>\nPhorbol 12-myristate 13-acetate, PMA<\/td>\nMCE\u8ca8\u865fHY-18739<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#50-63-5<\/td>\n\u78f7\u9178\u6c2f\u55b9 Chloroquine phosphate<\/td>\nMCE\u8ca8\u865fHY-17589<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 9003-11-6<\/td>\nPoloxamer 407<\/td>\nMCE\u8ca8\u865fHY-D1005<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#150347-59-4<\/td>\nCFSE\u87a2\u5149\u67d3\u6599<\/td>\nMCE\u8ca8\u865fHY-D0938<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 9025-71-2<\/td>\n\u55ae\u5be7\u9176(Tannase)<\/td>\nMCE\u8ca8\u865fHY-P2877<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 941678-49-5<\/td>\nRuxolitinib<\/td>\nMCE\u8ca8\u865fHY-50856<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#9002-92-0<\/td>\nPolidocanol<\/td>\nMCE\u8ca8\u865fHY-B2106<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#HY-100579<\/td>\nFerrostatin-1 (Synonyms: Fer-1)<\/td>\nMCE\u8ca8\u865f HY-100579<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#154-23-4<\/td>\n\u5152\u8336\u7d20(Catechin)<\/td>\nMCE\u8ca8\u865f HY-N0898<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 2225728-57-2<\/td>\nFT895\u5f37\u6548\u9078\u64c7\u6027 HDAC11 \u6291\u5236\u5291<\/td>\nMCE\u8ca8\u865f HY-112285<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 5471-63-6<\/td>\n1,3-\u4e8c\u82ef\u57fa\u7570\u82ef\u4e26\u544b\u5583 (DPBF)<\/td>\nMCE\u8ca8\u865f HY-W011664<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS# 2225728-57-2<\/td>\nAkaLumine hydrochloride<\/td>\nMCE\u8ca8\u865fHY-112641A<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#203115-63-3<\/td>\nWRN \u89e3\u65cb\u9176\u6291\u5236\u5291NSC 617145<\/td>\nMCE\u8ca8\u865f \u00a0HY-110185<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#2244-11-3<\/td>\nAlloxan hydrate<\/td>\nMCE\u8ca8\u865fHY-W017227<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#23491-44-3<\/td>\nHoechst 33258<\/td>\nMCE\u8ca8\u865fHY-15558<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#18883-66-4<\/td>\nStreptozotocin<\/td>\nMCE\u8ca8\u865fHY-13753<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n
MCE(MedChemexpress)<\/td>\nCAS#554435-83-5<\/td>\nDeferasirox (Fe3+ chelate)<\/td>\nMCE\u8ca8\u865f\u00a0HY-16564<\/td>\n\u7522\u54c1\u9023\u7d50<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

MCE (MedChem Express) Atezolizumab MCE\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\uff0c\u63d0\u4f9b\u7a2e\u985e\u9f4a\u5168\u7684 […]<\/p>\n","protected":false},"author":3,"featured_media":52093,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5369],"tags":[5473,6867,6866,6869,6865,6868],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/39803"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=39803"}],"version-history":[{"count":8,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/39803\/revisions"}],"predecessor-version":[{"id":52898,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/39803\/revisions\/52898"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/52093"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=39803"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=39803"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=39803"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}