{"id":29340,"date":"2021-09-13T16:10:39","date_gmt":"2021-09-13T08:10:39","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=29340"},"modified":"2023-11-13T11:53:21","modified_gmt":"2023-11-13T03:53:21","slug":"elikine-human-il-4-%e9%85%b5%e7%b4%a0%e5%85%8d%e7%96%ab%e5%88%86%e6%9e%90%e7%9b%92-%e8%b2%a8%e8%99%9fket6015","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=29340","title":{"rendered":"EliKine\u2122 Human IL-4 \u9175\u7d20\u514d\u75ab\u5206\u6790\u76d2 | Abbkine\u8ca8\u865fKTE6015"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><strong><span style=\"color: #33cccc; font-size: 12pt;\">EliKine\u2122 Human IL-4 \u9175\u7d20\u514d\u75ab\u5206\u6790\u76d2 | \u8ca8\u865fKTE6015 <span style=\"color: #ff9900;\">3.125 pg\/mL- 200 pg\/mL<\/span><\/span><\/strong><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/11\/%E5%93%81%E7%89%8C%E5%8C%85%E8%A3%9D-ABBKINE_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1.jpg\" \/><\/p>\n<p>IL 4; IL4; BCGF-1; BCGF1; BSF1; IL-4; MGC79402; B cell growth factor 1; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1<\/p>\n<p>IL-4 \u662f\u4e00\u7a2e\u9577 129 \u500b\u6c28\u57fa\u9178\u7684\u5206\u6ccc\u86cb\u767d\u3002 IL-4 \u662f\u4e00\u7a2e\u4e3b\u8981\u7531\u6d3b\u5316\u7684 T \u6dcb\u5df4\u7d30\u80de\u3001\u80a5\u5927\u7d30\u80de\u548c\u55dc\u9e7c\u6027\u7c92\u7d30\u80de\u7522\u751f\u7684\u7d30\u80de\u56e0\u5b50\u3002 \u5b83\u901a\u904e\u4f5c\u7528\u65bc\u591a\u7a2e\u7d30\u80de\u985e\u578b\u800c\u5177\u6709\u591a\u7a2e\u514d\u75ab\u53cd\u61c9\u8abf\u7bc0\u529f\u80fd\u3002 IL-4 \u53c3\u8207\u591a\u500b B \u7d30\u80de\u6d3b\u5316\u904e\u7a0b\u3002 \u5b83\u662f DNA \u5408\u6210\u7684\u5171\u523a\u6fc0\u5291\u3002 \u5b83\u8a98\u5c0e\u975c\u606f B \u7d30\u80de\u4e0a II \u985e MHC \u5206\u5b50\u7684\u8868\u9054\u3002 \u5b83\u589e\u5f37\u4e86 IgE \u548c IgG1 \u7684\u5206\u6ccc\u548c\u7d30\u80de\u8868\u9762\u8868\u9054\u3002 \u5b83\u9084\u8abf\u7bc0\u6dcb\u5df4\u7d30\u80de\u548c\u55ae\u6838\u7d30\u80de\u4e0a IgE (CD23) \u7684\u4f4e\u89aa\u548c\u529b Fc \u53d7\u9ad4\u7684\u8868\u9054\u3002 IL-4 \u6b63\u5411\u8abf\u7bc0\u5de8\u566c\u7d30\u80de\u4e2d IL31RA \u7684\u8868\u9054\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2022\/12\/ABBKINE-ELISA-KIT-%E7%B9%AA%E5%9C%96-%E7%89%A9%E7%A8%AE.jpg\" alt=\"\" width=\"499\" height=\"467\" \/><\/p>\n<table class=\"pro-info-table\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>Kit components<\/td>\n<td>\u2022 Human IL-4 microplate<br \/>\n\u2022 Human IL-4 standard<br \/>\n\u2022 Human IL-4 detect antibody<br \/>\n\u2022 EliKine\u2122 Streptavidin-HRP<br \/>\n\u2022 Standard diluent<br \/>\n\u2022 Assay buffer<br \/>\n\u2022 HRP substrate<br \/>\n\u2022 Stop solution<br \/>\n\u2022 Wash buffer<br \/>\n\u2022 Plate covers.<\/td>\n<\/tr>\n<tr>\n<td>Features &amp; Benefits<\/td>\n<td>EliKine\u2122 Human IL-4 ELISA Kit has high sensitivity and excellent specificity for detection of Human IL-4. No significant cross-reactivity or interference between Human IL-4 and analogues was observed.<\/td>\n<\/tr>\n<tr>\n<td>Calibration range<\/td>\n<td>3.125 pg\/mL- 200 pg\/mL<\/td>\n<\/tr>\n<tr>\n<td>Limit of detection<\/td>\n<td>1.5 pg\/mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Abbkine\u63d0\u4f9b\u4e00\u7cfb\u5217Elikine \u514d\u75ab\u767c\u708e\u76f8\u95dcELISA\u5206\u6790\u5957\u7d44; \u5176\u4e2d\u5305\u62ec\u517174\u7a2e\uff0c CCL2\u3001CCL3 \u3001sICAM-1 (CD54)\u00a0\u3001Human CRP\u00a0\u3001Human EGF\u3001Human bFGF\u3001Human G-CSF\u00a0\u3001Human GM-CSF\u3001Human HGF\u3001\u00a0Human IFN-\u03b1\u00a0\u3001Human IFN-\u03b3\u3001Human IL-1\u03b1\u3001Human IL-2 \u3001Human IL-1\u03b2 \u3001Human IL-4 \u3001Human IL-5\u3001Human IL-6 \u3001Human IL-8\u3001Human IL-10\u3001Human IL-12 p70\u00a0\u3001Human IL-13\u3001Human IL-17\u3001Human IL-18\u3001Human IL-22\u3001Human IL-23\u3001Human Leptin\u3001Human MMP-9\u3001Human \u03b2-NGF \u3001Human Resistin\u3001\u00a0Human TGF-\u03b21\u3001Human TIMP-1\u3001Human TNF-\u03b1\u3001Human VEGF\u00a0\u3001Human IgG\u3001Mouse CCL2\u3001Mouse GM-CSF\u3001Mouse IFN-\u03b3\u3001IL-1\u03b1\u00a0\u3001IL-1\u03b2\u00a0\u3001IL-2\u3001\u00a0IL-4\u00a0\u3001IL-5\u00a0\u3001\u00a0IL-6\u00a0\u3001\u00a0IL-10\u00a0\u3001IL-12 p70\u00a0\u3001IL-17\u3001IL-22\u00a0\u3001EliKine\u2122 Mouse TGF-\u03b21 \u3001Mouse TNF-\u03b1\u00a0\u3001\u00a0Mouse VEGF\u3001Rat Interferon Gamma (IFN-\u03b3)\u00a0\u3001Mouse IgG ELISA\u3001Rat IL-1\u03b2\u3001Rat IL-2\u00a0\u3001Rat IL-4\u00a0\u3001IL-6\u00a0\u3001\u00a0IL-17 \u3001Rat TGF-\u03b21\u00a0\u3001Rat TNF-\u03b1\u3001Rat VEGF\u00a0\u3001Human \u03b2-hCG\u3001Human LH\u3001Human FSH\u00a0\u3001\u00a0Human Prolactin\u3001Human TSH\u3001Testosterone\u3001Progesterone\u3001Estradiol\u00a0\u3001Free Triiodothyronine\u3001Free Thyroxine (fT4)\u00a0\u3001Triiodothyronine (T3)\u3001Thyroxine (T4)\u00a0\u3001Human PD-1\u00a0\u3001Human PD-L1 ELISA\u8a66\u5291\u76d2<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/11\/ABBKINE-ELISA-KIT%E5%85%A7%E5%AE%B9.png\" \/><\/p>\n<p>\u9175\u7d20\u9023\u7d50\u514d\u75ab\u5438\u9644\u6e2c\u5b9a\u6cd5\uff08ELISA\uff09\u662f\u4e00\u7a2e\u5e38\u7528\u65bc\u6e2c\u91cf\u751f\u7269\u6a23\u672c\u4e2d\u7684\u6297\u9ad4(antibodies)\u3001\u6297\u539f( antigens)\u3001\u86cb\u767d\u8cea(proteins)\u548c\u7cd6\u86cb\u767d( glycoproteins )\u7684\u514d\u75ab\u5b78\u6e2c\u5b9a\u3002\u4e00\u4e9b\u4f8b\u5b50\u5305\u62ec\uff1aHIV \u611f\u67d3( HIV infection)\u7684\u8a3a\u65b7\u3001\u598a\u5a20\u8a66\u9a57(pregnancy tests)\u4ee5\u53ca\u7d30\u80de\u4e0a\u6e05\u6db2\u6216\u8840\u6e05\u4e2d\u7d30\u80de\u56e0\u5b50(cytokines)\u6216\u53ef\u6eb6\u6027\u53d7\u9ad4(soluble receptors)\u7684\u6e2c\u91cf\u3002 ELISA\u539f\u7406\u53ef\u5206\u70ba\u593e\u5fc3ELISA(sandwich ELISA)\u3001\u7af6\u722d\u6027ELISA(competitive ELISA )\u548c\u9593\u63a5ELISA(competitive ELISA )\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/11\/ELISA-KIT%E5%8E%9F%E7%90%86.jpg\" width=\"493\" height=\"290\" \/><\/p>\n<p><strong><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/11\/1EliKine\u2122-Human-IL-4-\u9175\u7d20\u514d\u75ab\u5206\u6790\u76d2-Abbkine\u8ca8\u865fKTE6015.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/strong><\/p>\n<p><strong style=\"color: #993300; font-size: 12pt;\">\u7d30\u80de\u56e0\u5b50(Cytokine)\u529f\u80fd<\/strong><\/p>\n<p>\u7d30\u80de\u56e0\u5b50(Cytokine)\u5177\u6709\u591a\u7a2e\u751f\u7269\u5b78\u529f\u80fd\u3002\u5b83\u662f\u6025\u6027\u671f\u53cd\u61c9(acute phase response)\u7684\u6709\u6548\u8a98\u5c0e\u5291\u3002\u5728B\u7d30\u80de(B-cells)\u6700\u7d42\u5206\u5316\u70baIg\u5206\u6ccc\u7d30\u80de(Ig-secreting cells)\u7684\u6700\u7d42\u5206\u5316\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528\uff0c\u53c3\u8207\u6dcb\u5df4\u7d30\u80de(lymphocyte)\u548c\u55ae\u6838\u7d30\u80de(monocyte)\u7684\u5206\u5316\u3002\u5b83\u8a98\u5c0e\u9aa8\u9ad3\u7624(myeloma)\u548c\u6f3f\u7d30\u80de\u7624(plasmacytoma growth)\u751f\u9577\uff0c\u4e26\u8a98\u5c0e\u795e\u7d93\u7d30\u80de\u5206\u5316(differentiation)\u3002\u4f5c\u7528\u65bcB\u7d30\u80de(B-cells)\uff0cT\u7d30\u80de(T-cells)\uff0c\u809d\u7d30\u80de(hepatocytes)\uff0c\u9020\u8840\u7956\u7d30\u80de(hematopoeitic progenitor cells)\u548cCNS\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u7d30\u80de\u3002\u4e5f\u53ef\u4ee5\u4f5c\u70ba\u808c\u8089\u56e0\u5b50(myokine)\u3002\u5b83\u5728\u808c\u8089\u6536\u7e2e\u5f8c\u6392\u5165\u8840\u6db2\uff0c\u4e26\u8d77\u5230\u589e\u52a0\u8102\u80aa\u5206\u89e3\u548c\u6539\u5584\u80f0\u5cf6\u7d20\u62b5\u6297(insulin resistance)\u7684\u4f5c\u7528\u3002<\/p>\n<p><span style=\"font-size: 12pt; color: #993300;\"><strong>\u708e\u6027\u7d30\u80de\u56e0\u5b50<\/strong><\/span><\/p>\n<p>\u708e\u75c7\u7531\u591a\u7a2e\u53ef\u6eb6\u6027\u56e0\u5b50\u4ecb\u5c0e\uff0c\u5305\u62ec\u4e00\u7d44\u7a31\u70ba\u7d30\u80de\u56e0\u5b50\u7684\u5206\u6ccc\u591a\u80bd\u3002\u708e\u6027\u7d30\u80de\u56e0\u5b50\u53ef\u5206\u70ba\u5169\u985e\uff1a\u53c3\u8207\u6025\u6027\u708e\u75c7\u7684\u7d30\u80de\u56e0\u5b50\u548c\u8ca0\u8cac\u4efb\u7684\u7d30\u80de\u56e0\u5b50\u3002\u708e\u75c7\u662f\u7d44\u7e54\u5c0d\u640d\u50b7\u7684\u53cd\u61c9\uff0c\u5176\u7279\u5fb5\u662f\u5728\u6025\u6027\u671f\u4ee5\u589e\u52a0\u7684\u8840\u6d41\u91cf\u548c\u8840\u7ba1\u901a\u900f\u6027\u4ee5\u53ca\u9ad4\u6db2\uff0c\u767d\u7d30\u80de\u548c\u708e\u6027\u4ecb\u8cea\uff08\u4f8b\u5982\u7d30\u80de\u56e0\u5b50\uff09\u7684\u7a4d\u7d2f\u70ba\u7279\u5fb5\u3002\u5e7e\u7a2e\u7d30\u80de\u56e0\u5b50\u5728\u4ecb\u5c0e\u6025\u6027\u708e\u75c7\u53cd\u61c9\u4e2d\u8d77\u95dc\u9375\u4f5c\u7528\uff0c\u5373IL-1\uff0cTNF-\u03b1\uff0cIL-6\uff0cIL-11\uff0cIL-8\u548c\u5176\u4ed6\u8da8\u5316\u56e0\u5b50\uff0cG-CSF\u548cGM-CSF\u3002<\/p>\n<p>\u5df2\u77e5\u53ef\u4ecb\u5c0e\u6162\u6027\u708e\u75c7\u904e\u7a0b\u7684\u7d30\u80de\u56e0\u5b50\u53ef\u5206\u70ba\u53c3\u8207\u9ad4\u6db2\u708e\u75c7\u7684\u7d30\u80de\u56e0\u5b50\uff0c\u4f8b\u5982IL-3\uff0cIL-4\uff0cIL-5\uff0cIL-6\uff0cIL-7\uff0cIL-9\uff0cIL-10\uff0cIL- 13\uff0c\u8f49\u5316\u751f\u9577\u56e0\u5b50b\uff08TGF-b\uff09\uff0c\u4ee5\u53ca\u90a3\u4e9b\u6709\u52a9\u65bc\u7d30\u80de\u708e\u75c7\u7684\u56e0\u5b50\uff0c\u4f8b\u5982IL-1\uff0cIL-2\uff0cIL-3\uff0cIL-4\uff0cIL-7\uff0cIL-9\uff0cIL-10\uff0c IL-12\uff0c\u5e72\u64fe\u7d20\uff08IFN\uff09\uff0cIFN-g\u8a98\u5c0e\u56e0\u5b50\uff08IGIF\uff09\uff0cTGF-b\u548cTNF-a\u548c-b\u3002\u708e\u75c7\u7570\u5e38\u662f\u4e00\u5927\u985e\u75be\u75c5\uff0c\u662f\u8a31\u591a\u4eba\u985e\u75be\u75c5\u7684\u57fa\u790e\u3002\u7d30\u80de\u56e0\u5b50\u662f\u5bbf\u4e3b\u5c0d\u611f\u67d3\uff0c\u514d\u75ab\u53cd\u61c9\uff0c\u708e\u75c7\u548c\u5275\u50b7\u53cd\u61c9\u7684\u8abf\u7bc0\u5291\u3002\u4e00\u4e9b\u7d30\u80de\u56e0\u5b50\u8d77\u4f7f\u75be\u75c5\u60e1\u5316\u7684\u4f5c\u7528\uff08\u4fc3\u708e\u7d30\u80de\u56e0\u5b50\uff09\uff0c\u800c\u53e6\u4e00\u4e9b\u7d30\u80de\u56e0\u5b50\u8d77\u6e1b\u8f15\u708e\u75c7\u548c\u4fc3\u9032\u7652\u5408\u7684\u4f5c\u7528\uff08\u6297\u708e\u7d30\u80de\u56e0\u5b50\uff09\u3002<\/p>\n<p>\u767d\u4ecb\u7d20-1\uff08Interleukin-1, IL-1\uff09\u662f\u6709\u53f2\u4ee5\u4f86\u6700\u65e9\u7684\u7d30\u80de\u56e0\u5b50(cytokines)\u4e4b\u4e00\u3002\u5b83\u7684\u6700\u521d\u767c\u73fe\u662f\u53ef\u80fd\u8a98\u767c\u767c\u71d2(fever)\uff0c\u63a7\u5236\u6dcb\u5df4\u7d30\u80de(lymphocytes)\uff0c\u589e\u52a0\u9aa8\u9ad3\u7d30\u80de\u6578\u91cf(bone marrow cells)\u4e26\u5f15\u8d77\u9aa8\u95dc\u7bc0\u9000\u5316\u7684\u56e0\u7d20\u3002\u6b64\u6642\uff0cIL-1\u4ee5\u5176\u4ed6\u5e7e\u7a2e\u540d\u7a31\u70ba\u4eba\u6240\u77e5\uff0c\u5305\u62ec\u5167\u6e90\u6027\u71b1\u539f(endogenous pyrogen)\uff0c\u6dcb\u5df4\u7d30\u80de\u6d3b\u5316\u56e0\u5b50(lymphocyte activating factor)\uff0c\u9020\u8840\u7d20-1(haemopoetin-1)\u548c\u55ae\u6838\u7d30\u80de\u56e0\u5b50(mononuclear cell factor)\u7b49\u3002\u5927\u7d04\u57281984\u5e74\u81f31985\u5e74\u9593\uff0c\u79d1\u5b78\u5bb6\u5011\u8b49\u5be6IL-1\u5be6\u969b\u4e0a\u7531\u5169\u7a2e\u4e0d\u540c\u7684\u86cb\u767d\u8cea\u7d44\u6210\uff0c\u73fe\u5728\u7a31\u70baIL-1\u03b1\u548cIL-1\u03b2\uff0c\u5b83\u5011\u5c6c\u65bc\u7a31\u70ba\u767d\u7d30\u80de\u4ecb\u7d201\u8d85\u5bb6\u65cf\u7684\u7d30\u80de\u56e0\u5b50\u5bb6\u65cf\u3002 IL-1\u03b2\u7531\u5de8\u566c\u7d30\u80de(macrophages)\uff0c\u55ae\u6838\u7d30\u80de(monocytes)\u548c\u6a39\u7a81\u72c0\u7d30\u80de(dendritic cells)\u7522\u751f\u3002<\/p>\n<p>IFN-\u03b3\uff08IFN-gamma, \u5e72\u64fe\u7d20-\u03b3\uff09\u662f\u4fc3\u708e(proinflammatory)\u7d30\u80de\u56e0\u5b50(cytokine)\u7684\u539f\u578b(prototype)\uff0c\u7531\u591a\u7a2e\u514d\u75ab\u7d30\u80de(immune cells)\u5728\u708e\u6027(inflammatory)\u689d\u4ef6\u4e0b\u7522\u751f\uff0c\u7279\u5225\u662f\u7531T\u7d30\u80de(T cells)\u548cNK\u7d30\u80de(NK cells)\u7522\u751f\u3002\u5b83\u901a\u904e\u4fc3\u9032Th1\u7d30\u80de\u7684\u767c\u80b2(development)\u548c\u6fc0\u6d3b(activation)\uff0c\u55ae\u6838\u7d30\u80de(monocytes)\u548c\u5de8\u566c\u7d30\u80de(macrophage)\u7684\u5316\u5b78\u5f15\u8a98(chemoattraction)\u548c\u6fc0\u6d3b(activation)\uff0c\u6297\u539f\u5448\u905e\u5206\u5b50(antigen presentation molecules)\u7684\u4e0a\u8abf\u4ee5\u53caB\u7d30\u80de\u4e2d\u7684\u514d\u75ab\u7403\u86cb\u767d\u985e\u5225\u8f49\u63db(immunoglobulin class switching)\uff0c\u5728\u5bbf\u4e3b\u9632\u79a6\u4e2d\u8d77\u95dc\u9375\u4f5c\u7528\u3002\u5b83\u9084\u5177\u6709\u6297\u75c5\u6bd2(antiviral)\uff0c\u6297\u589e\u6b96(antiproliferative)\u548c\u51cb\u4ea1\u4f5c\u7528(apoptotic)\u3002\u53e6\u5916\uff0cIFN-\u03b3\u901a\u904e\u4fc3\u9032\u8abf\u7bc0\u6027T\u7d30\u80de\u7684\u767c\u80b2\u4e26\u6291\u5236Th17\u7d30\u80de\u5206\u5316\u800c\u5145\u7576\u6297\u708e\u4ecb\u8cea\u3002 IFN-\u03b3\u4e8c\u805a\u9ad4\u901a\u904e\u5169\u500bIFN-\u03b3R1\u548c\u5169\u500bIFN-\u03b3R2\u4e9e\u57fa\u7684\u53d7\u9ad4\u8907\u5408\u7269\u767c\u51fa\u4fe1\u865f\u3002<\/p>\n<p>\u767d\u7d30\u80de\u4ecb\u7d2017 (Interleukin 17, IL17)<\/p>\n<p>IL-17\u57fa\u56e0\u7de8\u78bc( IL-17 gene)\u7684\u86cb\u767d\u8cea\u662f\u7531\u6d3b\u5316\u7684T\u7d30\u80de(activated T cells)\u6240\u7522\u751f\u7684\u4fc3\u767c\u708e\u7d30\u80de\u6fc0\u7d20\u3002\u6b64\u7d30\u80de\u6fc0\u7d20\u8abf\u7bc0 NF-\u03baB \u548c\u7d72\u88c2\u539f\u6d3b\u5316\u86cb\u767d\u6fc0\u9176(mitogen-activated protein kinases)\u7684\u6d3b\u6027\u3002\u9019\u7a2e\u7d30\u80de\u6fc0\u7d20(cytokine )\u53ef\u4ee5\u523a\u6fc0 IL6 \u548c\u74b0\u6c27\u5408\u9176-2 (cyclooxygenase-2, PTGS2\/COX-2) \u7684\u8868\u9054\uff0c\u4e26\u589e\u5f37\u4e00\u6c27\u5316\u6c2e (nitric oxide, NO) \u7684\u7522\u751f\u3002\u9ad8\u6c34\u5e73\u7684\u9019\u7a2e\u7d30\u80de\u6fc0\u7d20\u8207\u591a\u7a2e\u6162\u6027\u767c\u708e\u6027\u75be\u75c5\u6709\u95dc\uff0c\u5305\u62ec\u985e\u98a8\u6fd5\u6027\u95dc\u7bc0\u708e(rheumatoid arthritis)\u3001\u725b\u76ae\u766c(psoriasis )\u548c\u591a\u767c\u6027\u786c\u5316\u75c7(multiple sclerosis)\u3002<\/p>\n<p>\u767d\u8840\u7403\u4ecb\u7d20-8\uff08Interleukin-8, IL8)<\/p>\n<p>IL-8\u57fa\u56e0\u7de8\u78bc(IL-8 gene)\u7684\u86cb\u767d\u8cea\u662fCXC\u8da8\u5316\u56e0\u5b50\u5bb6\u65cf(CXC chemokine family)\u7684\u6210\u54e1\u3002\u9019\u7a2e\u8da8\u5316\u56e0\u5b50(chemokine )\u662f\u767c\u708e\u53cd\u61c9(inflammatory response)\u7684\u4e3b\u8981\u4ecb\u8cea\u4e4b\u4e00\u3002\u9019\u7a2e\u8da8\u5316\u56e0\u5b50\u7531\u591a\u7a2e\u7d30\u80de\u985e\u578b\u5206\u6ccc\u3002\u5b83\u5177\u6709\u5316\u5b78\u5f15\u8a98\u5291( chemoattractant)\u7684\u4f5c\u7528\uff0c\u4e5f\u662f\u4e00\u7a2e\u6709\u6548\u7684\u8840\u7ba1\u751f\u6210\u56e0\u5b50(angiogenic factor)\u3002 IL-8\u57fa\u56e0\u88ab\u8a8d\u70ba\u5728\u7d30\u652f\u6c23\u7ba1\u708e\uff08\u4e00\u7a2e\u7531\u75c5\u6bd2\u611f\u67d3\u5f15\u8d77\u7684\u5e38\u898b\u547c\u5438\u9053\u75be\u75c5\uff09\u7684\u767c\u75c5\u6a5f\u5236(pathogenesis )\u4e2d\u767c\u63ee\u4f5c\u7528\u3002 IL-8\u57fa\u56e0(IL-8 gene )\u548cCXC\u8da8\u5316\u56e0\u5b50\u57fa\u56e0\u5bb6\u65cf(CXC chemokine gene family)\u7684\u5176\u4ed610\u500b\u6210\u54e1\u5728\u5b9a\u4f4d\u65bc\u67d3\u8272\u9ad44q( chromosome 4q)\u7684\u5340\u57df\u4e2d\u5f62\u6210\u8da8\u5316\u56e0\u5b50\u57fa\u56e0\u7c07(chemokine gene cluster )\u3002<\/p>\n<ul>\n<li>\u8acb\u52ff\u6df7\u7528\u4e0d\u540c\u8a66\u5291\u76d2\u4e2d\u7684\u7d44\u5206\uff0c\u6216\u5728\u8a66\u5291\u76d2\u5230\u671f\u65e5\u671f\u4e4b\u5f8c\u4f7f\u7528\u8a66\u5291\u3002<\/li>\n<li>\u6253\u958b\u4e4b\u524d\uff0c\u8b93\u6240\u6709\u8a66\u5291\u81f3\u5c11\u52a0\u5ba4\u6eab30\u5206\u9418\u3002<\/li>\n<li>\u7528\u8a66\u5291\u9810\u6e05\u6d17\u79fb\u6db2\u5668\u5438\u982d\uff0c\u70ba\u6bcf\u500b\u6a23\u54c1\uff0c\u6a19\u6e96\u6db2\u548c\u8a66\u5291\u4f7f\u7528\u65b0\u9bae\u7684\u79fb\u6db2\u5668\u5438\u982d\uff0c\u4ee5\u514d\u6c61\u67d3\u3002<\/li>\n<li>\u672a\u4f7f\u7528\u7684\u5b54\u5fc5\u9808\u5728\u63d0\u4f9b\u7684\u5bc6\u5c01\u888b\u4e2d\u65bc4\u00b0C\u4e7e\u71e5\u3002<\/li>\n<li>\u5fb9\u5e95\u6df7\u5408\u5c0d\u65bc\u7d50\u679c\u975e\u5e38\u91cd\u8981\u3002\u5efa\u8b70\u6bcf10\u5206\u9418\u4f7f\u7528\u4f4e\u983b\u632f\u76ea\u5668\u6216\u7a0d\u7a0d\u6416\u52d5\u624b\u3002<\/li>\n<li>\u5efa\u8b70\u6240\u6709\u6a23\u54c1\u548c\u6a19\u6e96\u54c1\u4e00\u5f0f\u5169\u4efd\u6216\u4e00\u5f0f\u4e09\u4efd\u9032\u884c\u6e2c\u5b9a\u3002<\/li>\n<\/ul>\n<table width=\"1277\">\n<tbody>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">\u7522\u54c1\u8ca8\u865f<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">\u00a0\u7269\u7a2e<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">\u54c1\u9805\u5167\u5bb9<\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">\u9748\u654f\u5ea6<\/span><\/td>\n<td width=\"738\"><span style=\"color: #808080;\">\u7522\u54c1\u9023\u7d50\u8cc7\u6599<\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=24727\">KTE7009<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">mouse<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">Mouse\u00a0<a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=24727\">IL-6 ELISA kit<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">\u00a07.5 pg\/ml-120 pg\/ml<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=24727\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=25661\">KTE6013<\/a>\u00a0\u00a0<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=25661\">\u4eba\u767d\u4ecb\u7d20IL-1\u03b2(Interleukin 1\u03b2)\u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><u>7.8 pg\/ml-500 pg\/ml<\/u>,<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=25661\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36764\">KTE6017<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36764\">\u4eba IL-6 ELISA \u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><u>3.125 pg\/ml-200 pg\/m<\/u>l<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=36764\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36729\"><u>KTE6030<\/u><\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">\u4eba<a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36729\"><u>TGF-\u03b21<\/u><u>\uff08\u8f49\u5316\u751f\u9577\u56e0\u5b50<\/u><u>\u03b21<\/u><u>\uff09<\/u><u>ELISA<\/u><u>\u8a66\u5291\u76d2<\/u><\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">15.6 pg\/ml-1000 pg\/ml<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=36729\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=25855\">KTE6032<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=25855\"><em><u>TNF<\/u><\/em>&#8211;<em><u>\u03b1<\/u><\/em>\u00a0Alpha\u578b\u816b\u7624\u58de\u6b7b\u56e0\u5b50 ELISA\u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><u>7.8 pg\/ml-500 pg\/ml<\/u><\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=25855\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE7005<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">mouse<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">\u767d\u4ecb\u7d20-1\u03b2\uff08Interleukin-1\u03b2, IL-1\u03b2\uff09ELISA\u8a66\u5291\u76d2<\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">\u00a0<u>15.6 pg\/ml-1000 pg\/ml<\/u><\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=25506\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36773\">KTE7014<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Mouse<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36773\">TGF-beta1\u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">15.6 pg\/ml-1000 pg\/ml<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=36773\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=29819\">KTE7015<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Mouse<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=29819\">\u5c0f\u9f20 TNF-\u03b1 ELISA \u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><u>3.9 pg\/mL-250 pg\/mL<\/u><\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=29819\"><span style=\"color: #ff0000;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36650\">KTE9001<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36650\">\u767d\u7d30\u80de\u4ecb\u7d20 1 \u03b2\u6aa2\u6e2c\u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><u>62.5 pg\/ml-4000 pg\/ml<\/u>,<\/span><\/td>\n<td width=\"738\"><a href=\"http:\/\/biopioneer.com.tw\/?p=36650\"><span style=\"color: #ff0000;\"><span style=\"color: #ff9900;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36797\">KTE6011<\/a><\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"http:\/\/biopioneer.com.tw\/?p=36797\">\u00a0<u>FN-\u03b3<\/u>\u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">7.8 pg\/mL-500 pg\/mL<\/span><\/td>\n<td width=\"738\"><span style=\"color: #ff9900;\"><a style=\"color: #ff9900;\" href=\"http:\/\/biopioneer.com.tw\/?p=36797\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/a><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6018<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #999999;\"><a style=\"color: #999999;\" href=\"https:\/\/biopioneer.com.tw\/?p=46782&amp;preview=true\"> \u767d\u8840\u7403\u4ecb\u7d20-8 IL-8 ELISA \u8a66\u5291\u76d2<\/a><\/span><\/td>\n<td width=\"210\"><span style=\"color: #999999;\">7.8 pg\/mL-500 pg\/mL<\/span><\/td>\n<td width=\"738\"><span style=\"color: #ff0000;\"><a href=\"https:\/\/biopioneer.com.tw\/?p=46782&amp;preview=true\"><span style=\"color: #ff9900;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6022<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #999999;\">\u767d\u8840\u7403\u4ecb\u7d20-17\u8a66\u5291\u76d2<\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\">7.8 pg\/mL-500 pg\/mL<\/span><\/td>\n<td width=\"738\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"https:\/\/biopioneer.com.tw\/?p=46790\"><span style=\"color: #ff9900;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6019<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">Human IL-10 \u8a66\u5291\u76d2<\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><span style=\"font-size: 12pt;\">2.35 pg\/ml-150 pg\/ml<\/span><\/span><\/td>\n<td width=\"738\"><span style=\"color: #808080;\"><a style=\"color: #808080;\" href=\"https:\/\/biopioneer.com.tw\/?p=29342\"><span style=\"color: #ff9900;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6032<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">TNF-\u03b1 Alpha\u578b\u816b\u7624\u58de\u6b7b\u56e0\u5b50ELISA\u8a66\u5291\u76d2<\/span><\/td>\n<td width=\"210\"><span style=\"color: #808080;\"><span style=\"font-size: 12pt;\">\u00a0<u>7.8 pg\/ml-500 pg\/ml<\/u>,<\/span><\/span><\/td>\n<td width=\"738\"><span style=\"color: #ff0000;\"><a href=\"https:\/\/biopioneer.com.tw\/?p=25855\"><span style=\"color: #ff9900;\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/span><\/a><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6905<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">TSH\u7532\u72c0\u817a\u4fc3\u9032\u7d20\u6aa2\u6e2c<\/span><\/td>\n<td width=\"210\"><span style=\"color: #999999;\"><span style=\"font-size: 12pt;\"><u>0.3 mIU\/L-12 mIU\/L<\/u><\/span><\/span><\/td>\n<td width=\"738\"><span style=\"color: #ff0000;\"><span style=\"color: #ff9900;\"><a href=\"https:\/\/biopioneer.com.tw\/?p=33789\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/a><\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td width=\"98\"><span style=\"color: #808080;\">KTE6036<\/span><\/td>\n<td width=\"73\"><span style=\"color: #808080;\">Human<\/span><\/td>\n<td width=\"158\"><span style=\"color: #808080;\">Human PD-L1 ELISA Kit\u8a66\u5291<\/span><\/td>\n<td width=\"210\"><span style=\"color: #999999;\"><span style=\"font-size: 12pt;\">12.5 pg\/mL &#8211; 800 pg\/mL<\/span><\/span><\/td>\n<td width=\"738\"><span style=\"color: #ff0000;\"><span style=\"color: #ff9900;\"><a href=\"https:\/\/biopioneer.com.tw\/?p=32564\">&lt;&lt;\u66f4\u591a\u8cc7\u6599&gt;&gt;<\/a><\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/11\/ABBKINE.jpg\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>EliKine\u2122 Human IL-4 \u9175\u7d20\u514d\u75ab\u5206\u6790\u76d2 | \u8ca8\u865fKTE6015 3.125 pg\/mL- 20 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":36554,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5262,452,3],"tags":[1009],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29340"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29340"}],"version-history":[{"count":7,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29340\/revisions"}],"predecessor-version":[{"id":46850,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/29340\/revisions\/46850"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/36554"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29340"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29340"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29340"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}