{"id":23446,"date":"2020-02-04T12:15:22","date_gmt":"2020-02-04T04:15:22","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=23446"},"modified":"2022-07-19T17:36:08","modified_gmt":"2022-07-19T09:36:08","slug":"%e7%b4%b0%e8%83%9e%e8%89%b2%e7%b4%a0p450-2d6-%e8%b2%a8%e8%99%9f7873","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=23446","title":{"rendered":"\u7d30\u80de\u8272\u7d20P450 2D6 | \u8ca8\u865f7873"},"content":{"rendered":"

\u7d30\u80de\u8272\u7d20P450 2D6 | <\/strong>\u8ca8\u865f<\/strong>7873<\/a><\/span><\/p>\n

EZCyp\u2122 Active Human Cytochrome P450 2D6<\/em><\/strong><\/p>\n

\u00a0<\/em><\/strong>\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>\u7d30\u80de\u8272\u7d20P450 2D6\uff08Cytochrome P450 2D6, CYP2D6\uff0cEC 1.14.14.1\uff09\u662f\u5fae\u7c92\u9ad4\u7570\u6e90\u751f\u7269\u4ee3\u8b1d\u9176(microsomal xenobiotic metabolism enzymes.)\u7684\u7d30\u80de\u8272\u7d20P450\u55ae\u6c27\u5316\u9176\uff08cytochrome P450 monooxidase , CYP\uff09\u5bb6\u65cf\u7684\u6210\u54e1\u3002 CYP\u662f\u8ca0\u8cacI\u671f\u751f\u7269\u8f49\u5316\u53cd\u61c9\u7684\u819c\u7d50\u5408\u8840\u7d05\u86cb\u767d(membrane-bound hemeproteins)\uff0c\u5176\u4e2d\u89aa\u8102\u6027\u85e5\u7269(lipophilic drugs)\u548c\u5176\u4ed6\u7570\u7a2e\u751f\u7269\u5316\u5408\u7269(hemeproteins responsible)\u88ab\u8f49\u5316\u70ba\u89aa\u6c34\u6027\u66f4\u9ad8\u7684\u7522\u7269(hydrophilic products)\uff0c\u4ee5\u4fc3\u9032\u4eba\u9ad4\u6392\u6cc4\u3002 CYP2D6\u50ac\u5316\u5177\u6709\u82b3\u9999\u74b0(aromatic ring)\u548c\u6c2e\u539f\u5b50(nitrogen atom)\u7684\u89aa\u8102\u6027\u9e7c\u57fa\u7684\u6c27\u5316\uff0c\u4e26\u5728\u809d\u548c\u8166\u7d44\u7e54\u4e2d\u9ad8\u5ea6\u8868\u9054\u3002 \u8a72\u9176\u8ca0\u8cac\u4eba\u985e\u901a\u5e38\u4f7f\u7528\u7684\u6240\u6709\u5c0f\u5206\u5b50\u85e5\u7269\uff08\u7279\u5225\u662f\u7cbe\u795e\u85e5\u7269psychiatric drugs\uff0c\u4f8b\u5982\u6297\u6291\u9b31\u85e5antidepressants\uff0c\u6297\u7cbe\u795e\u75c5\u85e5antipsychotics\u548c\u8208\u596e\u5291stimulants\uff09\u4e2d\u8fd125\uff05\u7684\u4ee3\u8b1d\u3002 BioVision\u7684EZCyp\u21222D6\u662f\u4e00\u7a2e\u900f\u5316\u548c\u7a69\u5b9a\u7684\u4e7e\u71e5\u9175\u6bcd\u7c89\u88fd\u5291\uff0c\u5176\u4e2d\u542b\u6709\u5728\u540c\u4e00\u88fd\u5291\u4e2d\u5171\u540c\u8868\u9054\u7684\u91cd\u7d44\u4ebaCYP2D6\u548c\u91cd\u7d44\u4ebaP450 NADPH\u6c27\u5316\u9084\u539f\u9176\u3002<\/p>\n

\"\"<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nCytochrome P450 2D6, Cyt2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, Active CYP2D6, human cyp2d, recombinant CYP2D6, CYP2D6, CPD6, CYP2D, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver\/kidney microsomal antigen 1<\/td>\n<\/tr>\n
Gene Symbol<\/strong><\/td>\nCYP2D6<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n1565<\/td>\n<\/tr>\n
Accession #<\/strong><\/td>\nP10635<\/td>\n<\/tr>\n
Source<\/strong><\/td>\nPichia pastoris<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nDry powder<\/td>\n<\/tr>\n
Physical Form Description<\/strong><\/td>\nLyophilized powder<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n55 Kda<\/td>\n<\/tr>\n
Purity by<\/strong><\/td>\nNA<\/td>\n<\/tr>\n
Endotoxin Level<\/strong><\/td>\nNA<\/td>\n<\/tr>\n
Biological Activity<\/strong><\/td>\nNA<\/td>\n<\/tr>\n
Reconstitution Instructions<\/strong><\/td>\n100 mM Potassium Phosphate buffer, pH 7.7<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nCentrifuge the vial prior to opening.<\/td>\n<\/tr>\n
Storage Conditions<\/strong><\/td>\n-20\u00b0C<\/td>\n<\/tr>\n
Shipping Conditions<\/strong><\/td>\nGel Pack<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a>\u00a0|\u00a0 <\/strong>Finnpipette F3 <\/strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a>\u00a0| \u00a0<\/strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a>\u00a0|\u00a0 <\/strong>Genereach<\/strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a>\u00a0 |\u00a0\u00a0 <\/strong>ELISA<\/strong>\u5100\u5668<\/strong><\/a><\/span><\/p>\n

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\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\u7d30\u80de\u8272\u7d20P450 2D6 | \u8ca8\u865f7873 EZCyp\u2122 Active Human Cytochrome P4 […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[1711],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23446"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23446"}],"version-history":[{"count":1,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23446\/revisions"}],"predecessor-version":[{"id":23447,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23446\/revisions\/23447"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23446"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}