{"id":23178,"date":"2020-01-30T14:46:31","date_gmt":"2020-01-30T06:46:31","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=23178"},"modified":"2022-07-19T17:37:55","modified_gmt":"2022-07-19T09:37:55","slug":"gck%ef%bc%88%e8%91%a1%e8%90%84%e7%b3%96%e6%bf%80%e9%85%b6%ef%bc%89%e6%8a%97%e9%ab%94-%e8%b2%a8%e8%99%9f3153-100","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=23178","title":{"rendered":"GCK\uff08\u8461\u8404\u7cd6\u6fc0\u9176\uff09\u6297\u9ad4 | \u8ca8\u865f3153-100"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=23178\">GCK\uff08\u8461\u8404\u7cd6\u6fc0\u9176\uff09\u6297\u9ad4 <strong>| <\/strong><strong>\u8ca8\u865f<\/strong>3153-100<\/a><\/span><\/p>\n<p><strong><em>GCK (Glucokinase) Antibody<\/em><\/strong><strong><em>\u00a0<\/em><\/strong><strong>\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>\u5df1\u7cd6\u6fc0\u9176(Hexokinases)\u4f7f\u8461\u8404\u7cd6(glucose)\u78f7\u9178\u5316(phosphorylate)\u4ee5\u7522\u751f6-\u78f7\u9178\u8461\u8404\u7cd6(glucose-6-phosphate)\uff0c\u5f9e\u800c\u4f7f\u8461\u8404\u7cd6\u9032\u5165\u7cd6\u9175\u89e3\u9014 (glycolytic pathway)\u3002 GCK\u57fa\u56e0\u7684\u53ef\u8b8a\u526a\u63a5(splicing)\u7522\u751f\u4e09\u7a2e\u7d44\u7e54\u7279\u7570\u6027\u5f62\u5f0f\u7684\u8461\u8404\u7cd6\u6fc0\u9176(glucokinase)\uff0c\u4e00\u7a2e\u5728\u80f0\u5cf6\u03b2\u7d30\u80de(pancreatic islet beta cells)\u4e2d\u767c\u73fe\uff0c\u5169\u7a2e\u5728\u809d\u81df(liver)\u4e2d\u767c\u73fe\u3002 \u8a72\u86cb\u767d\u8cea\u5b9a\u4f4d\u65bc\u7dda\u7c92\u9ad4(mitochondria)\u7684\u5916\u819c(outer membrane)\u3002 \u8207\u5176\u4ed6\u5f62\u5f0f\u7684\u5df1\u7cd6\u6fc0\u9176(hexokinase)\u4e0d\u540c\uff0c\u8a72\u9176\u4e0d\u53d7\u5176\u7522\u72696-\u78f7\u9178\u8461\u8404\u7cd6(glucose-6-phosphate)\u7684\u6291\u5236\uff0c\u4f46\u5728\u8461\u8404\u7cd6\u8c50\u5bcc\u6642\u4ecd\u4fdd\u6301\u6d3b\u6027\u3002 \u8a72\u57fa\u56e0\u7684\u7a81\u8b8a\u8207\u975e\u80f0\u5cf6\u7d20\u4f9d\u8cf4\u578b\u7cd6\u5c3f\u75c5\uff08non-insulin dependent diabetes mellitus, \u00a0NIDDM\uff09\u6709\u95dc\uff0c\u4e5f\u7a31\u70ba2\u578b\u5e74\u8f15\u6210\u5e74\u578b\u7cd6\u5c3f\u75c5\uff08maturity onset diabetes of the young, type 2, MODY2\uff09\u3002 \u7a81\u8b8a\u9084\u8207\u5b30\u5152\u6301\u7e8c\u6027\u9ad8\u80f0\u5cf6\u7d20\u4f4e\u8840\u7cd6\u75c7\uff08hyperinsulinemic hypoglycemia of infancy, PHHI\uff09\u76f8\u95dc\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/3\/1\/3153_1.jpg\" alt=\"\" \/><\/p>\n<table width=\"838\">\n<tbody>\n<tr>\n<td><strong>Cat # +Size<\/strong><\/td>\n<td>3153-100<\/td>\n<\/tr>\n<tr>\n<td><strong>Size<\/strong><\/td>\n<td>100 \u00b5g<\/td>\n<\/tr>\n<tr>\n<td><strong>Antibody Target<\/strong><\/td>\n<td>GCK (Glucokinase)<\/td>\n<\/tr>\n<tr>\n<td><strong>Host<\/strong><\/td>\n<td>Rabbit<\/td>\n<\/tr>\n<tr>\n<td><strong>Antibody Type<\/strong><\/td>\n<td>Polyclonal<\/td>\n<\/tr>\n<tr>\n<td><strong>Isotype<\/strong><\/td>\n<td>Rabbit IgG<\/td>\n<\/tr>\n<tr>\n<td><strong>Immunogen<\/strong><\/td>\n<td>Synthetic peptide selected from the N-terminal region of human GCK<\/td>\n<\/tr>\n<tr>\n<td><strong>Accession #<\/strong><\/td>\n<td>P35557<\/td>\n<\/tr>\n<tr>\n<td><strong>Gene ID<\/strong><\/td>\n<td>2645<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>Colorless liquid<\/td>\n<\/tr>\n<tr>\n<td><strong>Concentration<\/strong><\/td>\n<td>0.25 mg\/ml<\/td>\n<\/tr>\n<tr>\n<td><strong>Formulation<\/strong><\/td>\n<td>100 \u00b5g (0.25 mg\/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W\/V) sodium azide.<\/td>\n<\/tr>\n<tr>\n<td><strong>Purification<\/strong><\/td>\n<td>Affinity purified<\/td>\n<\/tr>\n<tr>\n<td><strong>Species Reactivity<\/strong><\/td>\n<td>Human, mouse<\/td>\n<\/tr>\n<tr>\n<td><strong>Application<\/strong><\/td>\n<td>ELISA, Western blot, Immunohistochemistry, Flow cytometry, Immunofluorescence<\/td>\n<\/tr>\n<tr>\n<td><strong>Application &amp; Usage<\/strong><\/td>\n<td>The antibody can be used for ELISA (0.25 \u00b5g\/ml), Western Blotting (0.5 \u2013 2.5 \u00b5g\/ml), Immunohistochemistry (2.5 \u2013 5.0 \u00b5g\/ml), Immunoflurescence (1:10 &#8211; 1:50), and Flow cytometry.<\/td>\n<\/tr>\n<tr>\n<td><strong>Handling<\/strong><\/td>\n<td>The antibody solution should be gently mixed before use.<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>-20 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shipping Conditions<\/strong><\/td>\n<td>Gel Pack<\/td>\n<\/tr>\n<tr>\n<td><strong>USAGE<\/strong><\/td>\n<td>For Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=9187\"><strong>\u4e7e\u6d74\u52a0\u71b1\u6c34\u6d74\u69fd<\/strong><\/a><strong>\u00a0|\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=16198\"><strong>Finnpipette F3 <\/strong><strong>\u5fae\u91cf\u5206\u6ce8\u5668<\/strong><\/a><strong>\u00a0| \u00a0<\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=17586\"><strong>\u8a66\u7ba1\u632f\u76ea\u5668 Vortex Mixer\u00a0<\/strong><\/a><strong>\u00a0|\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=19075\"><strong>Genereach<\/strong><strong>\u8ff7\u4f60\u578b\u5fae\u91cf\u96e2\u5fc3\u6a5f<\/strong><\/a><strong>\u00a0 |\u00a0\u00a0 <\/strong><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=1120\"><strong>ELISA<\/strong><strong>\u5100\u5668<\/strong><\/a><\/span><\/p>\n<p>\u5f15\u7528\u6587\u737b<\/p>\n<p>Huang et al., MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1\u03b1 and PPAR .\u00a0<a href=\"http:\/\/rnajournal.cshlp.org\/content\/21\/3\/385.abstract?maxtoshow=&amp;HITS=10&amp;hits=10&amp;RESULTFORMAT=&amp;andorexacttitle=and&amp;andorexacttitleabs=and&amp;fulltext=biovision&amp;andorexactfulltext=and&amp;searchid=1&amp;FIRSTINDEX=30&amp;fdate=3\/1\/2015&amp;tdate=3\/31\/2015&amp;resourcetype=HWCIT\">RNA,\u00a0Mar 2015; 21: 385 &#8211; 400.<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>GCK\uff08\u8461\u8404\u7cd6\u6fc0\u9176\uff09\u6297\u9ad4 | \u8ca8\u865f3153-100 GCK (Glucokinase) Antibody\u00a0\u7522\u54c1 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[1716],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23178"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23178"}],"version-history":[{"count":1,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23178\/revisions"}],"predecessor-version":[{"id":23181,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/23178\/revisions\/23181"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23178"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23178"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23178"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}