{"id":19726,"date":"2019-05-07T16:12:21","date_gmt":"2019-05-07T08:12:21","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=19726"},"modified":"2022-07-20T13:56:02","modified_gmt":"2022-07-20T05:56:02","slug":"cyclic-di-gmp-a-sting-ligand-cas-61093-23-0-%e8%b2%a8%e8%99%9fb2045","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=19726","title":{"rendered":"Cyclic-di-GMP | A STING ligand CAS #61093-23-0 \u8ca8\u865fB2045"},"content":{"rendered":"

Cyclic-di-GMP <\/strong>| <\/strong>\u8ca8\u865f<\/strong>B2045<\/strong><\/a><\/span><\/p>\n

A STING ligand<\/em><\/strong>\u00a0<\/em><\/strong><\/p>\n

\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>\u74b0\u72c0\u4e8c-GMP\uff08Cyclic di-GMP , di-GMP\uff09\u662f\u6700\u91cd\u8981\u548c\u6700\u5e38\u898b\u7684\u7d30\u83cc\u7b2c\u4e8c\u4fe1\u4f7f\u4e4b\u4e00\u3002 \u5b83\u6d89\u53ca\u8a31\u591a\u539f\u6838\u904e\u7a0b\uff0c\u5305\u62ec\u751f\u7269\u819c\u5f62\u6210(biofilm formation)\u3001\u904b\u52d5(motility)\uff0c\u6bd2\u529b (virulence) \u548c\u7d30\u80de\u9031\u671f (cell cycling)\u3002 c-di-GMP\u5728\u771f\u6838\u7d30\u80de\u4e2d\u4e5f\u5177\u6709\u529f\u80fd\u3002 \u5b83\u88ab\u8de8\u819c\u86cb\u767d (transmembrane protein) \u523a\u6fc0\u5e72\u64fe\u7d20\u57fa\u56e0\uff08STING\uff09\uff0c\u5c0e\u81f4\u5148\u5929\u514d\u75ab\u7cfb\u7d71 (innate immune system) \u7684\u6fc0\u6d3b (activation) \u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nGuanylyl-(3’\u21925′)-3′-guanylic acid, cyclic nucleotide; Cyclic diguanylate; 3′,5′-Cyclic diguanylic acid; c-di-GMP<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n61093-23-0<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2080H\u2082\u2084N\u2081\u2080O\u2081\u2084P\u2082<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n690.41<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226595%<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nH\u2082O (1 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nC1C2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)N)O)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C6NC(=NC7=O)N)O)OP(=O)(O1)O)O<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C20H24N10O14P2\/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34\/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)\/t5-,6-,9-,10-,11-,12-,17-,18-\/m1\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nPKFDLKSEZWEFGL-MHARETSRSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n6323195<\/td>\n<\/tr>\n
Handling<\/strong><\/td>\nProtect from air and moisture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Cyclic-di-GMP | \u8ca8\u865fB2045 A STING ligand\u00a0 \u7522\u54c1\u63cf\u8ff0\uff1a\u74b0\u72c0\u4e8c-GMP\uff08Cy […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1,3],"tags":[2216],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/19726"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19726"}],"version-history":[{"count":1,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/19726\/revisions"}],"predecessor-version":[{"id":19748,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/19726\/revisions\/19748"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=19726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=19726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}