{"id":18116,"date":"2018-11-08T10:49:37","date_gmt":"2018-11-08T02:49:37","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18116"},"modified":"2022-07-20T15:19:04","modified_gmt":"2022-07-20T07:19:04","slug":"ubiquitin-aldehyde%e9%87%8d%e7%bb%84%e6%b3%9b%e7%b4%a0%e9%86%9b-%e8%b2%a8%e8%99%9f4845-50","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=18116","title":{"rendered":"Ubiquitin Aldehyde\u4eba\u91cd\u7ec4\u6cdb\u7d20\u919b | \u8ca8\u865f4845-50"},"content":{"rendered":"<p><span style=\"color: #00ccff;\">\u4eba<a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=18116\"><strong style=\"color: #00ccff;\"><em>\u91cd\u7ec4\u6cdb\u7d20\u919b<\/em><\/strong> <strong style=\"color: #00ccff;\">| <\/strong><strong style=\"color: #00ccff;\">\u8ca8\u865f<\/strong><span style=\"color: #00ccff;\">4845-50<\/span><\/a><\/span><\/p>\n<p><strong><em>Ubiquitin Aldehyde, human recombinant-<\/em><\/strong><strong><em>An inhibitor of deubiquitinylating enzymes (DUBs)<\/em><\/strong><\/p>\n<p><strong>\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>Ubiquitin\u6cdb\u7d20\u7684C-\u672b\u7aef\u7518\u6c28\u9178\u7fa7\u57fa\u88ab\u5408\u6210\u4fee\u98fe\u6210\u919b\u3002\u86cb\u767d\u919b\uff08Ubiquitin Aldehyde , Ub-H\uff09\u53ef\u7528\u65bc\u9ad4\u5916\u7a69\u5b9aubiquitin-protein conjugates\u7db4\u5408\u7269\uff0c\u589e\u5f37\u5176\u5728\u7d30\u80de\u88c2\u89e3\u7269\u548c\u7d44\u7e54\u63d0\u53d6\u7269\u3002 Ub-H\u5c0d\u53bb\u6cdb\u7d20\u5316\u9176\u6d3b\u6027\u7684\u6291\u5236\u53ef\u7528\u65bc\u9451\u5b9a\u548c\u8b49\u5be6\u9019\u7a2e\u6d3b\u6027\u4e26\u78ba\u5b9a\u7279\u5b9a\u9176\u4e4b\u6291\u5236\u52d5\u529b\u5b78\u3002\u6cdb\u7d20\u919b\u53ef\u7528\u65bc\u6d3b\u6027\u5206\u6790\u5be6\u9a57\u548cDUB\u6291\u5291\u5291\u7279\u7570\u6027\u6e2c\u5b9a\u3002 \u5b83\u91dd\u5c0d\u4e94\u500b\u4e2d\u7684\u56db\u500b\u4e3b\u8981\u7684DUB\u5bb6\u65cf\uff1aUCH\uff0cUSP\uff0cOUT\u548cMJD\uff0c\u540c\u6642\u7559\u4e0bJAMM\u91d1\u5c6c\u86cb\u767d\u9176\u4e0d\u7f88\u3002 \u9700\u8981\u91dd\u5c0d\u6bcf\u7a2e\u7279\u5b9a\u61c9\u7528\u512a\u5316\u53cd\u61c9\u689d\u4ef6\u3002\u00a0\u6cdb\u7d20\u919b\u8207\u7279\u5b9a\u7684\u53bb\u6cdb\u7d20\u5316\u9176\uff08\u6a21\u64ec\u5929\u7136\u904d\u5728\u86cb\u767d\u5e95\u7269\u7684\u6291\u88fd\u5291\uff09\u7684Co-crystallization\u5171\u7d50\u6676\u4e5f\u5df2\u7528\u65bc\u63a2\u6e2cenzyme:substrate interactions\u3002\u63a8\u85a6\u521d\u59cb\u91cd\u7d44\u4eba\u6cdb\u7d20\u919b\u6fc3\u5ea6\u70ba1-5\u03bcM\u3002<\/p>\n<table width=\"838\">\n<tbody>\n<tr>\n<td><strong>Cat # +Size<\/strong><\/td>\n<td>4845-50<\/td>\n<\/tr>\n<tr>\n<td><strong>Size<\/strong><\/td>\n<td>50 \u03bcg<\/td>\n<\/tr>\n<tr>\n<td><strong>Alternate Name<\/strong><\/td>\n<td>Ubiquitin Aldehyde<\/td>\n<\/tr>\n<tr>\n<td><strong>Source<\/strong><\/td>\n<td>E. coli<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>Liquid<\/td>\n<\/tr>\n<tr>\n<td><strong>Physical Form Description<\/strong><\/td>\n<td>In 50 mM NaOAc pH 5.0<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Weight<\/strong><\/td>\n<td>8.6 kDa<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity by<\/strong><\/td>\n<td>&gt;97% Pure active Recombinant human Ubiquitin Aldehyde.<\/td>\n<\/tr>\n<tr>\n<td><strong>Biological Activity<\/strong><\/td>\n<td>UCHL3 activity with Ubiquitin-AMC measured in the presence of 17.5 nM and 0.1 nM Ubiquitin Aldehyde.<\/td>\n<\/tr>\n<tr>\n<td><strong>Handling<\/strong><\/td>\n<td>Centrifuge the vial prior to opening.<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>-80\u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shipping Conditions<\/strong><\/td>\n<td>Dry Ice<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eba\u91cd\u7ec4\u6cdb\u7d20\u919b | \u8ca8\u865f4845-50 Ubiquitin Aldehyde, human recombinan [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":18117,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[2504],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18116"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18116"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18116\/revisions"}],"predecessor-version":[{"id":18121,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18116\/revisions\/18121"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/18117"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18116"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18116"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18116"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}