{"id":18105,"date":"2018-11-06T13:37:58","date_gmt":"2018-11-06T05:37:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=18105"},"modified":"2022-12-01T11:02:09","modified_gmt":"2022-12-01T03:02:09","slug":"2-deoxy-d-glucose-%e8%91%a1%e8%90%84%e7%b3%96%e4%bb%a3%e8%ac%9d%e7%ab%b6%e7%88%ad%e6%80%a7%e6%8a%91%e5%88%b6%e5%8a%91-biovision%e8%b2%a8%e8%99%9fb1048-500","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=18105","title":{"rendered":"2-Deoxy-D-Glucose | \u8461\u8404\u7cd6\u4ee3\u8b1d\u7af6\u722d\u6027\u6291\u5236\u5291 BIOVISION\u8ca8\u865fB1048-500 ( ABCAM ab142242)"},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=18105\">2-Deoxy-D-Glucose <strong>| <\/strong><strong>\u8ca8\u865f<\/strong>B1048-500<\/a>\u00a0( ABCAM ab142242)<\/span><\/p>\n<p><strong><em>A competitive inhibitor of glucose metabolism.<\/em><\/strong><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/b\/1\/b1048.gif\" alt=\"\" \/><\/p>\n<p><strong>\u7522\u54c1\u63cf\u8ff0\uff1a<\/strong>2-Deoxy-D-Glucose 2-\u812b\u6c27-D-\u8461\u8404\u7cd6\u662f\u4e00\u7a2e\u8461\u8404\u91a3\u985e\u4f3c\u7269(glucose analog)\uff0c\u9577\u671f\u4ee5\u4f86\u4e00\u76f4\u88ab\u8a8d\u70ba\u662f\u8461\u8404\u7cd6\u4ee3\u8b1d(glucose metabolism)\u7684\u7af6\u722d\u6027\u6291\u5236\u5291(competitive inhibitor)\u3002 \u8f49\u904b\u5230\u7d30\u80de\u4e2d\u5f8c\uff0c2-DG\u88ab\u5df1\u7cd6\u6fc0\u9176(phosphorylated by hexokinase)\u78f7\u9178\u5316\u70ba2-DG-P\u3002 \u7136\u800c\uff0c\u8207G-6-P\u4e0d\u540c\uff0c2-DG-P\u4e0d\u80fd\u88ab\u78f7\u9178\u5df1\u7cd6\u7570\u69cb\u9176(phosphohexose isomerase)\u9032\u4e00\u6b65\u4ee3\u8b1d\uff0c\u78f7\u9178\u5df1\u7cd6\u7570\u69cb\u9176\u5c07G-6-P\u8f49\u5316\u70ba\u679c\u7cd6-6-\u78f7\u9178\u3002 2-\u812b\u6c27\u8461\u8404\u7cd6-P\u88ab\u6355\u7372\u4e26\u7a4d\u805a\u5728\u7d30\u80de\u4e2d\uff0c\u4e3b\u8981\u5728\u5df1\u7cd6\u6fc0\u9176\u78f7\u9178\u5316\u8461\u8404\u7cd6\u7684\u6b65\u9a5f\u4e2d\u5c0e\u81f4\u7cd6\u9175\u89e3\u7684\u6291\u5236\u3002 \u901a\u904e2-DG\u6291\u5236\u8a72\u9650\u901f\u6b65\u9a5f\u5c0e\u81f4\u7d30\u80deATP\u8017\u76e1\uff0c\u5c0e\u81f4\u7d30\u80de\u9031\u671f\u9032\u7a0b\u7684\u963b\u65b7\u548c\u9ad4\u5916\u7d30\u80de\u6b7b\u4ea1(cell cycle progression)\u3002<\/p>\n<p>ab142242 has been referenced in 3 publications.<\/p>\n<ul>\n<li>Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent.<\/li>\n<li>CAS Number: 154-17-6<\/li>\n<li>Purity: &gt; 97%<\/li>\n<li>Soluble in ethanol to 50 mM and in DMSO to 50 mM<\/li>\n<li>Form \/ State: Solid<\/li>\n<li>Source: Synthetic<\/li>\n<\/ul>\n<table width=\"837\">\n<tbody>\n<tr>\n<td><strong>Alternate Name<\/strong><\/td>\n<td>2-Deoxy-D-arabinohexose, 2-Deoxyglucose<\/td>\n<\/tr>\n<tr>\n<td><strong>Appearance<\/strong><\/td>\n<td>White to off-white solid<\/td>\n<\/tr>\n<tr>\n<td><strong>CAS #<\/strong><\/td>\n<td>154-17-6<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Formula<\/strong><\/td>\n<td>C\u2086H\u2081\u2082O\u2085<\/td>\n<\/tr>\n<tr>\n<td><strong>Molecular Weight<\/strong><\/td>\n<td>164.16<\/td>\n<\/tr>\n<tr>\n<td><strong>Purity<\/strong><\/td>\n<td>\u226598% GC<\/td>\n<\/tr>\n<tr>\n<td><strong>Solubility<\/strong><\/td>\n<td>H2O (&gt;15 mg\/ml) or DMSO (&gt;15 mg\/ml)<\/td>\n<\/tr>\n<tr>\n<td><strong>SMILES<\/strong><\/td>\n<td>C1C(C(C(OC1O)CO)O)O<\/td>\n<\/tr>\n<tr>\n<td><strong>InChi<\/strong><\/td>\n<td>InChI=1S\/C6H12O5\/c7-2-4-6(10)3(8)1-5(9)11-4\/h3-10H,1-2H2\/t3-,4-,5?,6+\/m1\/s1<\/td>\n<\/tr>\n<tr>\n<td><strong>InChi Key<\/strong><\/td>\n<td>PMMURAAUARKVCB-CERMHHMHSA-N<\/td>\n<\/tr>\n<tr>\n<td><strong>PubChem CID<\/strong><\/td>\n<td><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/439268\">439268<\/a><\/td>\n<\/tr>\n<tr>\n<td><strong>MDL Number<\/strong><\/td>\n<td>MFCD00151328<\/td>\n<\/tr>\n<tr>\n<td><strong>Handling<\/strong><\/td>\n<td>Protect from air and moisture<\/td>\n<\/tr>\n<tr>\n<td><strong>Storage Conditions<\/strong><\/td>\n<td>4\u00b0C<\/td>\n<\/tr>\n<tr>\n<td><strong>Shipping Conditions<\/strong><\/td>\n<td>Gel Pack<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2-Deoxy-D-Glucose | \u8ca8\u865fB1048-500\u00a0( ABCAM ab142242) A com [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[2507],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18105"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18105"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18105\/revisions"}],"predecessor-version":[{"id":36598,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/18105\/revisions\/36598"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}