{"id":17427,"date":"2018-08-07T16:44:13","date_gmt":"2018-08-07T08:44:13","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=17427"},"modified":"2022-07-20T16:12:32","modified_gmt":"2022-07-20T08:12:32","slug":"%e8%85%a6%e8%86%9c%e7%82%8e%e5%a5%88%e7%91%9f%e6%b0%8f%e7%90%83%e8%8f%8c%e7%9a%84%e5%9b%a0%e5%ad%90h%e7%b5%90%e5%90%88%e8%9b%8b%e7%99%bd%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%94-absoluteantibody%e8%b2%a8","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=17427","title":{"rendered":"\u8166\u819c\u708e\u5948\u745f\u6c0f\u7403\u83cc\u7684\u56e0\u5b50H\u7d50\u5408\u86cb\u767d\u55ae\u682a\u6297\u9ad4 | Absoluteantibody\u8ca8\u865fAb00445-1.1"},"content":{"rendered":"<p><strong>Fc Silent\u2122 Antibodies: Turning down the background noise<\/strong> <strong>\u53ea\u8981<\/strong><strong>\u8a0a<\/strong><strong>\u865f\u4e0d\u8981\u96dc<\/strong><strong>\u8a0a (Engineered Fc Domain)<\/strong><\/p>\n<p><span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=17427\">\u8166\u819c\u708e\u5948\u745f\u6c0f\u7403\u83cc\u7684\u56e0\u5b50H\u7d50\u5408\u86cb\u767d\u55ae\u682a\u6297\u9ad4 | <strong>\u8ca8\u865f<\/strong><strong>Ab00445-1.1<\/strong><\/a><\/span><\/p>\n<p>Anti-Factor H binding protein from N. meningitidis\u4f86\u81ea\u8166\u819c\u708e\u5948\u745f\u6c0f\u7403\u83cc\u7684\u56e0\u5b50H\u7d50\u5408\u86cb\u767d\u7684\u91cd\u7d44\u55ae\u514b\u9686\u6297\u9ad4\u3002 \u4f7f\u7528\u4f86\u81ea\u96dc\u4ea4\u7624JAR5\u7684\u5177\u6709\u53ef\u8b8a\u5340\uff08\u5373\u7279\u7570\u6027\uff09\u7684AbAb\u91cd\u7d44\u5e73\u53f0\u88fd\u9020\u3002<\/p>\n<p><strong>Species and Isotype:\u00a0<\/strong>Mouse IgG1, kappa<br \/>\n<strong>Clone Number:\u00a0<\/strong>JAR5<br \/>\n<strong>UniProt Accession Number of Target Protein:\u00a0<\/strong>C6KHT4<br \/>\n<strong>Alternative Name(s) of Target:\u00a0<\/strong>FHbp<br \/>\n<strong>Published Application(s):\u00a0<\/strong>ELISA; WB; Blocking<br \/>\n<strong>Published Species Reactivity:\u00a0<\/strong>Neisseria meningitidis<br \/>\n<strong>Immunogen:\u00a0<\/strong>Genome-derived neisserial Antigen 1870.<br \/>\n<strong>Specificity:\u00a0<\/strong>This antibody binds to FHbp with a Kd of 54 pM.<br \/>\n<strong>Application Notes:\u00a0<\/strong>This antibody binds to N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. This antibody shows strong inhibition of human FH binding.<br \/>\n<strong>Antibody First Published in:\u00a0<\/strong><br \/>\nWelsch et al. Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine. Journal of Immunology 2004; 172(9):5606-5615\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15100304\">PMID:15100304<\/a><strong>Note on publication:\u00a0<\/strong>Describes the generation of several antibodies against eneisserial antigen 1870 and study of their passive protection against bacteremia.<\/p>\n<table width=\"574\">\n<tbody>\n<tr>\n<td><strong>\u00a0Cat. No.<\/strong><\/td>\n<td><strong>Product Description<\/strong><\/td>\n<td><strong>Clone<\/strong><\/td>\n<td><strong>Size<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-01&amp;type=Polyclonal\"><strong>1070-01<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-UNLB<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-02&amp;type=Polyclonal\"><strong>1070-02<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-FITC<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-03&amp;type=Polyclonal\"><strong>1070-03<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-TRITC<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-04&amp;type=Polyclonal\"><strong>1070-04<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-AP<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mL<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-05&amp;type=Polyclonal\"><strong>1070-05<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-HRP<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mL<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-07&amp;type=Polyclonal\"><strong>1070-07<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-TXRD<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-08&amp;type=Polyclonal\"><strong>1070-08<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-BIOT<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-09&amp;type=Polyclonal\"><strong>1070-09<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-PE<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">0.5 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-09S&amp;type=Polyclonal\"><strong>1070-09S<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-PE<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">0.25 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-11L&amp;type=Polyclonal\"><strong>1070-11L<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-APC<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">0.5 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-11S&amp;type=Polyclonal\"><strong>1070-11S<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-APC<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">0.25 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-15&amp;type=Polyclonal\"><strong>1070-15<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-CY5<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-19&amp;type=Polyclonal\"><strong>1070-19<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-APC\/CY7<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">0.25 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-30&amp;type=Polyclonal\"><strong>1070-30<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-Alexa Fluor<\/strong><strong><sup>\u00ae<\/sup><\/strong><strong>\u00a0488<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<tr>\n<td width=\"135\"><a href=\"https:\/\/www.southernbiotech.com\/?catno=1070-31&amp;type=Polyclonal\"><strong>1070-31<\/strong><\/a><\/td>\n<td><strong>Goat Anti-Mouse IgG<\/strong><strong><sub>1<\/sub><\/strong><strong>, Human ads-Alexa Fluor<\/strong><strong><sup>\u00ae<\/sup><\/strong><strong>\u00a0647<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td width=\"60\">1.0 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fc Silent\u2122 Antibodies: Turning down the background nois [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":12266,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[2629],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17427"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17427"}],"version-history":[{"count":2,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17427\/revisions"}],"predecessor-version":[{"id":17429,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/17427\/revisions\/17429"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/12266"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}