{"id":16394,"date":"2018-04-19T14:54:40","date_gmt":"2018-04-19T06:54:40","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=16394"},"modified":"2022-07-20T16:52:50","modified_gmt":"2022-07-20T08:52:50","slug":"cd80-%e9%87%8d%e7%b5%84%e8%9b%8b%e7%99%bd-cd80-human-recombinant-biovision%e8%b2%a8%e8%99%9f7383","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=16394","title":{"rendered":"CD80 \u91cd\u7d44\u86cb\u767d | CD80 human recombinant BioVision\u8ca8\u865f7383"},"content":{"rendered":"

Human CellExp\u2122 CD80, human recombinant\u91cd\u7d44\u86cb\u767d | <\/strong>\u8ca8\u865f<\/strong>7383<\/a><\/span><\/p>\n

Plays a role in induction of innate immune responses by activating NF-\u03baB-signaling pathway in macrophages<\/em><\/strong><\/p>\n

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\u7522\u54c1<\/strong>\u63cf\u8ff0\uff1a<\/strong>B7-1\u548cB7-2\u4ee5\u53ca\u5b83\u5011\u7684\u53d7\u9ad4CD28\u548cCTLA4\u69cb\u6210\u8abf\u7bc0T\u548cB\u7d30\u80de\u61c9\u7b54\u7684\u4e3b\u8981\u5171\u523a\u6fc0\u9014\u5f91\u4e4b\u4e00\u3002\u5118\u7ba1CTLA4\u548cCD28\u90fd\u53ef\u4ee5\u7d50\u5408\u76f8\u540c\u7684\u914d\u9ad4\uff0c\u4f46CTLA4\u4ee5\u6bd4CD28\u9ad820-100\u500d\u7684\u89aa\u548c\u529b\u7d50\u5408B71\u548cB72\uff0c\u4e26\u53c3\u8207\u514d\u75ab\u61c9\u7b54\u7684\u4e0b\u8abf\u3002 B\u6dcb\u5df4\u7d30\u80de\u6d3b\u5316\u6297\u539fB7-1\uff08\u4e5f\u7a31\u70baB7\uff09\u4e5f\u7a31\u70ba\u5206\u531680\uff08CD80\uff09\u7c07\uff0c\u662f\u7d30\u80de\u8868\u9762\u514d\u75ab\u7403\u86cb\u767d\u8d85\u5bb6\u65cf\u7684\u6210\u54e1\uff0c\u4e26\u5728\u6d3b\u5316\u7684B\u7d30\u80de\uff0c\u6d3b\u5316\u7684T\u7d30\u80de\uff0c\u5de8\u566c\u7d30\u80de\u548c\u6a39\u7a81\u7d30\u80de\u4e0a\u8868\u9054\u3002\u5b83\u662fT\u7d30\u80de\u8868\u9762\u4e0a\u5169\u7a2e\u4e0d\u540c\u86cb\u767d\u7684\u914d\u9ad4\uff1aCD28\uff08\u7528\u65bc\u81ea\u9ad4\u8abf\u7bc0\u548c\u7d30\u80de\u9593\u7d50\u5408\uff09\u548cCTLA-4\uff08\u7528\u65bc\u6e1b\u5f31\u8abf\u7bc0\u548c\u7d30\u80de\u89e3\u96e2\uff09\u3002 CD80\u8207CD86\u4e00\u8d77\u8d77\u4f5c\u7528\u4ee5\u5f15\u767cT\u7d30\u80de\u3002 CD80\u901a\u904e\u6fc0\u6d3b\u5de8\u566c\u7d30\u80de\u4e2d\u7684NF-\u03baB\u4fe1\u865f\u901a\u8def\u5728\u8a98\u5c0e\u5148\u5929\u6027\u514d\u75ab\u53cd\u61c9\u4e2d\u8d77\u4f5c\u7528\u3002 CD80\u56e0\u6b64\u88ab\u8a8d\u70ba\u662f\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\u548c\u5404\u7a2e\u764c\u75c7\u7684\u6709\u5e0c\u671b\u7684\u6cbb\u7642\u9776\u9ede\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nCD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7<\/td>\n<\/tr>\n
Gene Symbol<\/strong><\/td>\nCD80<\/td>\n<\/tr>\n
Gene ID<\/strong><\/td>\n941<\/td>\n<\/tr>\n
Accession #<\/strong><\/td>\nP33681<\/td>\n<\/tr>\n
Source<\/strong><\/td>\nHEK293 cells<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nLyophilized<\/td>\n<\/tr>\n
Physical Form Description<\/strong><\/td>\nLyophilized from 0.22 \u03bcm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\nThis protein is fused with 6\u00d7His tag at the C-terminus, has a calculated MW of 24.7 kDa. The predicted N-terminus is Val 35. DTT-reduced Protein migrates as 45-75 kDa due to different glycosylation.<\/td>\n<\/tr>\n
Purity by SDS-PAGE<\/strong><\/td>\n\u226595%<\/td>\n<\/tr>\n
Endotoxin Level<\/strong><\/td>\n<1 EU\/\u03bcg by LAL method<\/td>\n<\/tr>\n
Biological Activity<\/strong><\/td>\nMeasured by its ability to induce IL2 secretion by Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.01 – 0.1 \u00b5g\/mL in the presence of phytohaemagglutinin.<\/td>\n<\/tr>\n
Reconstitution Instructions<\/strong><\/td>\nCentrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 \u00b5g\/ml. Do not vortex. This solution can be stored at 2-8\u00b0C for up to 1 month. For extended storage, it is recommended to store at -20\u00b0C.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Human CellExp\u2122 CD80, human recombinant\u91cd\u7d44\u86cb\u767d | \u8ca8\u865f7383 Pla […]<\/p>\n","protected":false},"author":3,"featured_media":459,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[139],"tags":[2775],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/16394"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16394"}],"version-history":[{"count":1,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/16394\/revisions"}],"predecessor-version":[{"id":16395,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/16394\/revisions\/16395"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/459"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=16394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=16394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}