{"id":15482,"date":"2018-02-04T10:18:36","date_gmt":"2018-02-04T02:18:36","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=15482"},"modified":"2022-07-20T17:48:33","modified_gmt":"2022-07-20T09:48:33","slug":"acat1%e6%aa%b3%e6%a6%94%e9%b9%bc%e5%85%b1%e5%83%b9%e6%8a%91%e5%88%b6%e5%8a%91-biovision-cas300-08-3%e8%b2%a8%e8%99%9fb1824-100","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=15482","title":{"rendered":"ACAT1\u6ab3\u6994\u9e7c\u5171\u50f9\u6291\u5236\u5291 | Biovision CAS#300-08-3\u8ca8\u865fB1824-100\u00a0\u00a0"},"content":{"rendered":"

ACAT Inhibitors\u6291\u5236\u5291\u7cfb\u5217\u5546\u54c1<\/span><\/p>\n

Arecoline hydrobromide\u6291\u5236\u5291 | Biovision CAS#300-08-3\u8ca8\u865fB1824-100\u00a0\u00a0<\/a><\/span><\/p>\n

A covalent ACAT1 inhibitor<\/p>\n

\"\"<\/p>\n

\u7522\u54c1\u4ecb\u7d39\uff1aArecoline hydrobromide\u6ab3\u6994\u9e7c\u662fACAT1\u7684\u5171\u50f9\u6291\u5236\u5291\uff0c\u5176\u7d50\u5408\u4f75\u7834\u58deACAT1\u56db\u805a\u9ad4\uff08IC 50 =11.1\u03bcM\uff09\u3002 ACAT2\u548cDLAT\u4e0d\u53d7\u6291\u5236\u3002 \u7528\u6ab3\u6994\u9e7c\u8655\u7406\u7570\u7a2e\u79fb\u690d\u88f8\u9f20\u5c0e\u81f4\u816b\u7624\u8cea\u91cf\u7684\u5291\u91cf\u4f9d\u8cf4\u6027\u964d\u4f4e\u3002\u6bd2\u8548\u9e7c\u4e59\u91af\u81bd\u9e7c\u53d7\u9ad4M1-M5\uff08EC 50\u7bc4\u570d\u70ba7-410nM\uff09\u7684\u6fc0\u52d5\u5291\u3002\u53ef\u80fd\u5c0d\u7661\u5446\u75c7\u6709\u6548\u3002(\u7814\u7a76\u5c08\u7528)<\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/td>\n1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid, methyl ester, hydrobromide<\/td>\n<\/tr>\n
Appearance<\/td>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/td>\n300-08-3<\/td>\n<\/tr>\n
Molecular Formula<\/td>\nC\u2088H\u2081\u2083NO\u2082 \u2022 HBr<\/td>\n<\/tr>\n
Molecular Weight<\/td>\n236.11<\/td>\n<\/tr>\n
Purity<\/td>\n\u226598% by TLC<\/td>\n<\/tr>\n
Solubility<\/td>\nH\u2082O (>50 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/td>\nCN1CCC=C(C1)C(=O)OC.Br<\/td>\n<\/tr>\n
InChi<\/td>\nInChI=1S\/C8H13NO2.BrH\/c1-9-5-3-4-7(6-9)8(10)11-2;\/h4H,3,5-6H2,1-2H3;1H<\/td>\n<\/tr>\n
InChi Key<\/td>\nAXOJRQLKMVSHHZ-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/td>\n9301<\/td>\n<\/tr>\n
MDL Number<\/td>\nMFCD00039041<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u66f4\u591a\u9175\u7d20\u578b\u6291\u5236\u5291\u5546\u54c1: ACE\u6291\u5236\u5291\u985e<\/a> | AR\u6291\u5236\u5291\u985e<\/a> | AKR\u6291\u5236\u5291\u985e<\/a> | adenylyl cyclase \u6291\u5236\u5291\u985e<\/a> | AAC\u6291\u5236\u5291<\/a> | ACAT\u6291\u5236\u5291<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

ACAT Inhibitors\u6291\u5236\u5291\u7cfb\u5217\u5546\u54c1 Arecoline hydrobromide\u6291\u5236\u5291 | Biov […]<\/p>\n","protected":false},"author":3,"featured_media":15483,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[478,486],"tags":[2941],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15482"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15482"}],"version-history":[{"count":1,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15482\/revisions"}],"predecessor-version":[{"id":15484,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/15482\/revisions\/15484"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/15483"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}