{"id":13731,"date":"2017-09-07T13:03:06","date_gmt":"2017-09-07T05:03:06","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=13731"},"modified":"2022-07-21T10:44:03","modified_gmt":"2022-07-21T02:44:03","slug":"caspase-8%e8%83%b1%e5%a4%a9%e8%9b%8b%e7%99%bd%e9%85%b6-8%e6%8a%91%e5%88%b6%e5%8a%91-q-ietd-oph-%e8%b2%a8%e8%99%9f1176-5","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=13731","title":{"rendered":"Caspase-8\u6291\u5236\u5291 (Q-IETD-OPh) | \u80f1\u5929\u86cb\u767d\u9176-8\u6291\u5236\u5291\/Biovision\u8ca8\u865f1176-5"},"content":{"rendered":"

Next Generation Caspase Inhibitors<\/strong><\/span><\/p>\n

Caspases\u80f1\u5929\u86cb\u767d\u9176\u662f\u5df2\u77e5\u70ba\u51cb\u4ea1\u7684\u751f\u7406\u6b7b\u4ea1\u904e\u7a0b\u7684\u95dc\u9375\u6548\u61c9\u5206\u5b50\uff0cCaspases\u4e00\u4e9b\u53c3\u8207\u7d30\u80de\u56e0\u5b50\u7684\u6d3b\u5316\u800c\u4e0d\u662f\u7d30\u80de\u6b7b\u4ea1\uff0c\u5728\u6211\u5011\u7684\u5927\u90e8\u5206\u7d30\u80de\u4e2d\u4ee5inactive precursors (zymogens)\uff08\u9176\u539f\uff09\u5b58\u5728\uff0c\u4e00\u65e6\u88ab\u6fc0\u6d3b\u4f5c\u70ba\u800c\u6bba\u6b7b\u7d30\u80de\u3002 \u80f1\u5929\u86cb\u767d\u9176\u53ef\u4ee5\u901a\u904e\u5169\u7a2e\u65b9\u5f0f\u9032\u884c\u63a7\u5236\u3002 \u534a\u80f1\u5929\u51ac\u9176\u6d3b\u5316\u53ef\u4ee5\u901a\u904eFADD\uff0cAPAF-1\uff0cBcl-2\u5bb6\u65cf\u6210\u54e1\uff0cFLIP\u548cIAP\u7b49\u5206\u5b50\u4f86\u8abf\u7bc0\u3002Caspases\u80f1\u5929\u86cb\u767d\u9176\u53ef\u4ee5\u901a\u904e\u5404\u7a2einhibitors\u6291\u5236\u5291\u8207protease\u76f8\u4e92\u4f5c\u7528\u7684\u4f86\u63a7\u5236\u3002 Biovision\u63d0\u4f9b\u4e00\u7cfb\u5217Caspases\u80f1\u5929\u86cb\u767d\u9176\u6291\u5236\u5291 \uff0c\u6709\u6548\u4e14\u5177\u7d30\u80de\u53ef\u6ef2\u900f\u7684\uff0c\u4e0d\u53ef\u9006\u548c\u7121\u6bd2\u7684\u7279\u6027\uff0c\u53ef\u61c9\u7528\u65bcin-vitro\u53cain-vivo\u4e4b\u79d1\u5b78\u7814\u7a76\u3002<\/p>\n

\"\"<\/p>\n

Caspase-8<\/strong>\u80f1\u5929\u86cb\u767d\u9176-8<\/strong>\u6291\u5236\u5291<\/strong> (<\/strong>Q-IETD-OPh) <\/strong>\u00a0<\/strong>| <\/strong>\u8ca8\u865f1176-5<\/strong><\/a><\/span><\/p>\n

Caspase-8 Inhibitor, Q-IETD-OPh\u7b2c\u4e8c\u4ee3\u80f1\u5929\u86cb\u767d\u9176-3\u6291\u5236\u5291\uff0c\u6709\u6548\uff0c\u7d30\u80de\u53ef\u6ef2\u900f\uff0c\u4e0d\u53ef\u9006\u548c\u7121\u6bd2\u3002<\/p>\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nQ-IE(OMe)-TD(OMe)-OPh; Quinolyl-Ile-Glu(OMe)-Thr-Asp(OMe)-OPh<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nOff-white solid<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2083\u2088H\u2084\u2085F\u2082N\u2085O\u2081\u2081<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n785.78<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0Caspase inhibitor \u5546\u54c1<\/span>\u00a0\u00a0(Q-DEVD-Oph)\u00a0<\/a>\u00a0|\u00a0(Q-IETD-OPh)\u00a0<\/a>\u00a0|\u00a0(Q-LEHD-OPh)<\/a>\u00a0|(Q-VD-OPh)\u00a0<\/a>\u00a0|\u00a0\u00a0(Q-VD-OPh)<\/a>\u00a0|\u00a0(Boc-D-FM)\u00a0<\/a>\u00a0|\u00a0(Z-AEVD-FMK)<\/a>\u00a0|\u00a0\u00a0(Z-ATAD-FMK)<\/a>\u00a0|\u00a0<\/span><\/strong><\/p>\n

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\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Next Generation Caspase Inhibitors Caspases\u80f1\u5929\u86cb\u767d\u9176\u662f\u5df2\u77e5\u70ba\u51cb\u4ea1\u7684 […]<\/p>\n","protected":false},"author":3,"featured_media":625,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[84,128],"tags":[3225],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/13731"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13731"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/13731\/revisions"}],"predecessor-version":[{"id":13763,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/13731\/revisions\/13763"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/625"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13731"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13731"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13731"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}