{"id":11026,"date":"2017-06-23T16:21:41","date_gmt":"2017-06-23T08:21:41","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=11026"},"modified":"2022-07-21T17:35:15","modified_gmt":"2022-07-21T09:35:15","slug":"11026","status":"publish","type":"post","link":"https:\/\/biopioneer.com.tw\/?p=11026","title":{"rendered":"\u9223\u86cb\u767d\u9176I\u6291\u5236\u5291 | Calpain Inhibitor I, ALLN \u8ca8\u865f1834-25"},"content":{"rendered":"

Calpain Inhibitor I, ALLN <\/strong>\u00a0<\/a><\/span>\u00a0\u8ca8\u865f1834-25 <\/a><\/span>\u00a0 \u00a0 5-25MG<\/strong>\u5305\u88dd<\/strong><\/p>\n

A Calpain inhibitor<\/em><\/strong><\/p>\n

\u00a0<\/em><\/strong>\u7522\u54c1\u4ecb\u7d39: \u9223\u86cb\u767d\u9176I\uff08Ki = 190nM\uff09\uff0c\u9223\u86cb\u767d\u9176II\uff08Ki = 220nM\uff09\uff0c\u7d44\u7e54\u86cb\u767d\u9176B\uff08Ki = 150nM\uff09\u548c\u7d44\u7e54\u86cb\u767d\u9176L\uff08Ki = 0.5nM\uff09\u7684\u7d30\u80de\u53ef\u6ef2\u900f\u7684\u6291\u5236\u5291\u3002 \u6291\u5236\u4e2d\u6027\u534a\u80f1\u6c28\u9178\u86cb\u767d\u9176\u548c\u86cb\u767d\u9176\u9ad4\uff08Ki =6\u03bcM\uff09\u3002 \u53ef\u4ee5\u555f\u52d5HL-60\u7d30\u80de\u51cb\u4ea1\uff0c\u4f46\u963b\u65b7\u5730\u585e\u7c73\u677e\u8a98\u5c0e\u7684\u80f8\u817a\u7d30\u80de\u51cb\u4ea1\u548c\u74b0\u5df1\u9170\u4e9e\u80fa\u8a98\u5c0e\u7684\u7d30\u80de\u51cb\u4ea1\u3002 \u6291\u5236\u7d30\u80de\u9031\u671f\u86cb\u767dB\u964d\u89e3\uff0c\u4e26\u963b\u6b62\u7d30\u80de\u9031\u671f\u5728G1 \/ S\u548c\u9593\u671f\/\u5f8c\u671f\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nAc-LLnL-CHO, MG-101, N-Acetyl-L-leucyl-L-leucyl-L-norleucinal, N-Acetyl-Leu-Leu-Nle-al<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite powder<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n110044-82-1<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2082\u2080H\u2083\u2087N\u2083O\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n383.54<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226595% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (25 mg\/ml) or EtOH<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nCCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C20H37N3O4\/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25\/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)\/t16-,17-,18-\/m0\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nFMYKJLXRRQTBOR-BZSNNMDCSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n443118<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD00065505<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/strong><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Calpain Inhibitor I, ALLN \u00a0\u00a0\u8ca8\u865f1834-25 \u00a0 \u00a0 5-25MG\u5305\u88dd A Ca […]<\/p>\n","protected":false},"author":3,"featured_media":11027,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[478,486],"tags":[3592,3591],"_links":{"self":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/11026"}],"collection":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=11026"}],"version-history":[{"count":3,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/11026\/revisions"}],"predecessor-version":[{"id":11031,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/11026\/revisions\/11031"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/11027"}],"wp:attachment":[{"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=11026"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=11026"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=11026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}