{"id":9548,"date":"2017-04-18T14:26:42","date_gmt":"2017-04-18T06:26:42","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=9548"},"modified":"2022-07-22T14:26:31","modified_gmt":"2022-07-22T06:26:31","slug":"ps-341-a-proeasome-inhibitor%e6%8a%91%e5%88%b6%e5%8a%91-biovision%e8%b2%a8%e8%99%9f1846","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=9548","title":{"rendered":"PS-341-A proeasome inhibitor\u6291\u5236\u5291 | BioVision\u8ca8\u865f1846"},"content":{"rendered":"

PS-341 | A proeasome inhibitor<\/strong>\u6291<\/strong>\u5236<\/strong>\u5291 | <\/strong>\u8ca8\u865f<\/strong>1846<\/strong> \u00a0<\/strong><\/a><\/span><\/p>\n

\u7522\u54c1\u4ecb\u7d39: \u6709\u6548\uff08Ki = 0.6nM\uff09\uff0c\u7279\u7570\u6027\u548c\u53ef\u9006\u86cb\u767d\u9176\u9ad4\u6291\u5236\u5291\u3002 \u5b83\u6291\u5236IC 50\u70ba0.1\u03bcM\u7684H460\u7d30\u80de\uff08\u4eba\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7d30\u80de\u7cfb\uff09\u7684\u7d30\u80de\u589e\u6b96\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/strong><\/td>\nMG-341; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid<\/td>\n<\/tr>\n
Appearance<\/strong><\/td>\nWhite to off-white solid<\/td>\n<\/tr>\n
CAS #<\/strong><\/td>\n179324-69-7<\/td>\n<\/tr>\n
Molecular Formula<\/strong><\/td>\nC\u2081\u2089H\u2082\u2085BN\u2084O\u2084<\/td>\n<\/tr>\n
Molecular Weight<\/strong><\/td>\n384.24<\/td>\n<\/tr>\n
Purity<\/strong><\/td>\n\u226599% by HPLC<\/td>\n<\/tr>\n
Solubility<\/strong><\/td>\nDMSO (200mg\/ml) or EtOH (200 mg\/ml)<\/td>\n<\/tr>\n
SMILES<\/strong><\/td>\nB(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O<\/td>\n<\/tr>\n
InChi<\/strong><\/td>\nInChI=1S\/C19H25BN4O4\/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16\/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)\/t15-,17-\/m0\/s1<\/td>\n<\/tr>\n
InChi Key<\/strong><\/td>\nGXJABQQUPOEUTA-RDJZCZTQSA-N<\/td>\n<\/tr>\n
PubChem CID<\/strong><\/td>\n387447<\/a><\/td>\n<\/tr>\n
MDL Number<\/strong><\/td>\nMFCD09056737<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/strong><\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

PS-341 | A proeasome inhibitor\u6291\u5236\u5291 | \u8ca8\u865f1846 \u00a0 \u7522\u54c1\u4ecb\u7d39: \u6709\u6548\uff08K […]<\/p>\n","protected":false},"author":3,"featured_media":9549,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[3826],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9548"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9548"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9548\/revisions"}],"predecessor-version":[{"id":22203,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9548\/revisions\/22203"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/9549"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9548"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}