{"id":9424,"date":"2017-04-13T11:55:46","date_gmt":"2017-04-13T03:55:46","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=9424"},"modified":"2023-11-17T10:38:57","modified_gmt":"2023-11-17T02:38:57","slug":"%e7%b7%9a%e7%b2%92%e9%ab%94%e6%bb%b2%e9%80%8f%e6%80%a7transition-pore%e6%b8%ac%e5%ae%9a%e8%a9%a6%e5%8a%91%e7%9b%92-%e8%b2%a8%e8%99%9fk239-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=9424","title":{"rendered":"\u7dda\u7c92\u9ad4\u6ef2\u900f\u6027Transition Pore\u6e2c\u5b9a\u8a66\u5291\u76d2 | \u8ca8\u865fK239-100 (ab239704)"},"content":{"rendered":"

\u00a0\u7dda\u7c92\u9ad4\u6ef2\u900f\u6027Transition Pore\u6e2c\u5b9a\u8a66\u5291\u76d2<\/span><\/a><\/span><\/strong> | \u8ca8\u865f<\/strong>K239-100(ab239704)<\/strong><\/a><\/span><\/p>\n

Mitochondrial Permeability Transition Pore Assay Kit<\/em><\/strong><\/p>\n

\u7522\u54c1\u4ecb\u7d39<\/strong>:<\/strong> \u7dda\u7c92\u9ad4\u662f\u7d30\u80de\u7684\u529f\u7387\u4e2d\u5fc3\uff0c\u5728\u80fd\u91cf\u751f\u7522\u4e2d\u8d77\u8457\u81f3\u95dc\u91cd\u8981\u7684\u4f5c\u7528\u3002\u7dda\u7c92\u9ad4\u7684\u640d\u50b7\u6fc0\u6d3b\u8a98\u5c0e\u7d30\u80de\u51cb\u4ea1\u7684\u4fe1\u865f\u901a\u8def\u3002\u7dda\u7c92\u9ad4\u901a\u900f\u6027\u8f49\u63db\u5b54\uff08MPT\u5b54\u6216MPTP\uff09\u662f\u7531\u5167\u7dda\u7c92\u9ad4\u819c\u548c\u5916\u7dda\u7c92\u9ad4\u819c\u7d44\u6210\u7684\u975e\u7279\u7570\u6027\u901a\u9053\uff0c\u4f3c\u4e4e\u5728\u7d30\u80de\u6b7b\u4ea1\u671f\u9593\u53c3\u8207\u7dda\u7c92\u9ad4\u6210\u5206\u7684\u91cb\u653e\u3002 \u5728\u5065\u5eb7\u7d30\u80de\u4e2d\uff0cMPTP\u5728\u958b\u653e\u72c0\u614b\u548c\u9589\u5408\u72c0\u614b\u4e4b\u9593\u9583\u720d\uff0c\u4f46\u662f\u5728\u7d30\u80de\u6b7b\u4ea1\u904e\u7a0b\u4e2d\uff0cMPTP\u986f\u8457\u6539\u8b8a\u4e86\u7dda\u7c92\u9ad4\u7684\u901a\u900f\u6027\u3002 \u7d30\u80de\u8272\u7d20C\u91cb\u653e\u548c\u7dda\u7c92\u9ad4\u819c\u96fb\u4f4d\u7684\u55aa\u5931\u662f\u9023\u7e8c\u5b54\u6d3b\u5316\u5f8c\u7684\u3002BioVision\u7684\u7dda\u7c92\u9ad4\u6ef2\u900f\u6027\u904e\u6e21\u5b54\u6e2c\u5b9a\u8a66\u5291\u76d2\u63d0\u4f9b\u4e86\u901a\u904e\u6e2c\u91cfMPTP\u958b\u653e\u800c\u4e0d\u662f\u50c5\u4f9d\u8cf4\u65bc\u7dda\u7c92\u9ad4\u819c\u96fb\u4f4d\u4f86\u6e2c\u91cf\u7d30\u80de\u6b7b\u4ea1\u7684\u76f4\u63a5\u65b9\u6cd5\u3002<\/p>\n

\"\"<\/p>\n

\u7c92\u7dda\u9ad4\u901a\u900f\u6027\u8f49\u63db\u5b54\uff08 mitochondrial permeability transition pore, mPTP\u6216MPTP\uff1b\u4e5f\u7a31\u70baPTP\u3001mTP\u6216MTP\uff09\u662f\u5728\u67d0\u4e9b\u75c5\u7406\u689d\u4ef6\u4e0b, \u4f8b\u5982\u5275\u50b7\u6027\u8166\u640d\u50b7( traumatic brain injury)\u548c\u4e2d\u98a8(stroke)\u5728\u7c92\u7dda\u9ad4\u5167\u819c\u4e2d\u5f62\u6210\u7684\u86cb\u767d\u8cea\u3002\u958b\u653e\u53ef\u4ee5\u589e\u52a0\u7c92\u7dda\u9ad4\u819c\u5c0d\u5206\u5b50\u91cf\u5c0f\u65bc 1500 \u9053\u723e\u9813\u7684\u5206\u5b50\u7684\u6ef2\u900f\u6027\u3002\u6839\u64da\u7279\u5b9a\u7684\u751f\u7269\u74b0\u5883\uff0c\u901a\u900f\u6027\u8f49\u8b8a\u5b54\u3001\u7c92\u7dda\u9ad4\u819c\u901a\u900f\u6027\u8f49\u8b8a\uff08mPT \u6216 MPT\uff09\u7684\u8a98\u5c0e\u53ef\u5c0e\u81f4\u7c92\u7dda\u9ad4\u816b\u8139( mitochondrial swelling)\u548c\u7d30\u80de\u900f\u904e\u51cb\u4ea1\u6216\u58de\u6b7b\u800c\u6b7b\u4ea1( cell death)\u3002<\/p>\n\n\n\n\n\n\n\n\n\n
Size<\/strong><\/td>\n100 assays<\/td>\n<\/tr>\n
SKU+Size<\/strong><\/td>\nK239-100 (ab239704)<\/td>\n<\/tr>\n
Detection Method<\/strong><\/td>\nFlow cytometry (Ex 488 nm)<\/td>\n<\/tr>\n
Species Reactivity<\/strong><\/td>\nMammalian<\/td>\n<\/tr>\n
Applications<\/strong><\/td>\nMeasure mitochondrial permeability transition pore activity in cells
\nAssessment of physiological mediators and antibodies that affect cell viability\/cytotoxicity<\/td>\n<\/tr>\n
Features & Benefits<\/strong><\/td>\n\u2022 Simple procedure
\n\u2022 Fast, convenient and sensitive
\n\u2022 The assay provides a direct method of measuring mitochondrial permeability transition pore activation as an early marker of apoptosis<\/td>\n<\/tr>\n
Kit Components<\/strong><\/td>\n\u2022 MPTP Staining Dye
\n\u2022 CoCl2
\n\u2022 Ionomycin
\n\u2022 MPTP Wash Buffer<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0\u7dda\u7c92\u9ad4\u6ef2\u900f\u6027Transition Pore\u6e2c\u5b9a\u8a66\u5291\u76d2 | \u8ca8\u865fK239-100(ab239704) Mito […]<\/p>\n","protected":false},"author":3,"featured_media":8363,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5261,5380,129],"tags":[3847],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9424"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9424"}],"version-history":[{"count":8,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9424\/revisions"}],"predecessor-version":[{"id":47139,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/9424\/revisions\/47139"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/8363"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9424"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}