{"id":8709,"date":"2017-01-16T14:54:09","date_gmt":"2017-01-16T06:54:09","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=8709"},"modified":"2022-10-29T16:40:04","modified_gmt":"2022-10-29T08:40:04","slug":"ugt%e5%b0%bf%e8%8b%b7%e4%ba%8c%e7%a3%b7%e9%85%b8-%e8%91%a1%e9%86%a3%e9%86%9b%e9%85%b8%e8%bd%89%e7%a7%bb%e9%85%b6%e8%9e%a2%e5%85%89%e5%88%86%e6%9e%90%e5%a5%97%e7%b5%84-%e8%b2%a8%e8%99%9fk692-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=8709","title":{"rendered":"UGT\u5c3f\u82f7\u4e8c\u78f7\u9178 &#8211; \u8461\u91a3\u919b\u9178\u8f49\u79fb\u9176\u87a2\u5149\u5206\u6790\u5957\u7d44  | \u8ca8\u865fK692-100 (Abcam ab273331)"},"content":{"rendered":"<p><strong>\u5546\u54c1:<\/strong> <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"http:\/\/biopioneer.com.tw\/?p=8709\">UGT\u5c3f\u82f7\u4e8c\u78f7\u9178 &#8211; \u8461\u91a3\u919b\u9178\u8f49\u79fb\u9176\u87a2\u5149\u5206\u6790\u5957\u7d44 \u00a0| \u8ca8\u865fK692-100<\/a>\u00a0(Abcam ab273331)<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2021\/08\/%E5%8E%9F%E7%90%86%E8%88%87%E7%9F%A5%E8%AD%98-300x81.jpg\" alt=\"\u539f\u7406\u8207\u77e5\u8b58\" width=\"159\" height=\"41\" \/><\/p>\n<p>Biovision\u63d0\u4f9b\u4e00\u7cfb\u5217\u85e5\u7269\u4ee3\u8b1d\u5206\u6790\u5957\u7d44\uff1b\u5176\u4e2dUGT\u5c3f\u82f7\u4e8c\u78f7\u9178 &#8211; \u8461\u91a3\u919b\u9178\u8f49\u79fb\u9176\u87a2\u5149\u5206\u6790\u5957\u7d44\uff0c\u4ee5Fluorescence (Ex\/Em = 415\/502 nm) \u5075\u6e2c\uff1b\u5feb\u901f\u5f9e\u7d44\u7e54\u548c\u7d30\u80de\u88fd\u5099\u7684\u7d1a\u5206\u4e2d\u5929\u7136\/\u91cd\u7d44UGT\u6d3b\u6027\u7684\u5feb\u901f\u8a55\u4f30\u7be9\u9078\u85e5\u7269\u548c\u7528\u65bc\u8207\u5929\u7136\/\u91cd\u7d44UGT\u9176\u76f8\u4e92\u4f5c\u7528\u7684\u65b0\u914d\u9ad4\uff1b\u8a72\u6e2c\u5b9a\u5229\u7528\u5177\u6709\u5927\u7684\u65af\u6258\u514b\u65af\u4f4d\u79fb\uff08Ex \/ Em = 415 \/ 502nm\uff09\u7684\u9ad8\u5ea6\u87a2\u5149\u7684UGT\u5e95\u7269\uff0c\u5176\u5141\u8a31\u901a\u904e\u8ddf\u8e2a\u7576\u5e95\u7269\u8f49\u5316\u70ba\u975e\u87a2\u5149\u8461\u7cd6\u82f7\u9178\u6642\u87a2\u5149\u767c\u5c04\u7684\u4e0b\u964d\u4f86\u6e2c\u5b9aUGT\u6d3b\u6027\u3002\u591a\u540c\u529f\u9176\u5e95\u7269\u901a\u904e\u5e7e\u4e4e\u6240\u6709\u85e5\u7406\u5b78\u76f8\u95dc\u7684\u54fa\u4e73\u52d5\u7269UGT1A\u548cUGT2B\u9176\u88ab\u8461\u8404\u91a3\u919b\u9178\u5316\u3002\u901a\u904e\u6bd4\u8f03\u87a2\u5149\u640d\u5931\u8207\u5728\u4e0d\u5b58\u5728\u6240\u9700\u8f14\u56e0\u5b50UDPGA\u7684\u60c5\u6cc1\u4e0b\u9032\u884c\u7684\u5c0d\u7167\u53cd\u61c9\u4f86\u8a08\u7b97UGT\u6bd4\u6d3b\u6027\u3002\u8a72\u8a66\u5291\u76d2\u5305\u62ec\u5b54\u5f62\u6210\u80bd\u6297\u751f\u7d20\u963f\u62c9\u7f8e\u6c40\uff0c\u5176\u5141\u8a31UGT\u5e95\u7269\u548cUDPGA\u5feb\u901f\u64f4\u6563\u7a7f\u904e\u8102\u8cea\u819c\u4ee5\u9032\u5165\u4f4d\u65bc\u5fae\u7c92\u9ad4\u8154\u4e2d\u7684UGT\u6d3b\u6027\u4f4d\u9ede\u3002\u70ba\u4e86\u9a57\u8b49\u6e2c\u8a66\u914d\u9ad4\u5c0dUGT\u6d3b\u6027\u7684\u8abf\u7bc0\uff0c\u4e5f\u5305\u62ec\u96d9\u6c2f\u82ac\u9178\uff0c\u5927\u591a\u6578\u4eba\u548c\u56d3\u9f52\u985eUGT\u540c\u529f\u9176\u7684\u7af6\u722d\u6027\u6291\u88fd\u5291\u3002\u8a72\u6e2c\u5b9a\u662f\u9ad8\u5ea6\u9748\u654f\u7684\uff0c\u57f7\u884c\u7c21\u55ae\u548c\u9ad8\u901a\u91cf\u9069\u61c9\u6027\u3002\u8a72\u6e2c\u5b9a\u6cd5\u53ef\u4ee5\u6aa2\u6e2c\u751f\u7269\u6a23\u54c1\u4e2d\u5c0f\u65bc0.1mU\u7684UGT\u6d3b\u6027\u3002\u8a72\u8a66\u5291\u76d2\u542b\u6709\u8db3\u4ee5\u5728100\u03bcl\u53cd\u61c9\u9ad4\u7a4d\u4e0b\u9032\u884c100\u6b21\u53cd\u61c9\u7684\u5b8c\u6574\u8a66\u5291\u7d44\u3002<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/K\/6\/K692.jpg\" alt=\"\" \/>\u5c3f\u82f7\u4e8c\u78f7\u9178 &#8211; \u8461\u91a3\u919b\u9178\u8f49\u79fb\u9176\uff08UGT\uff0cEC 2.4.1.17\uff09\u662f\u5fae\u7c92\u9ad4\u819c\u7d50\u5408\u7cd6\u57fa\u8f49\u79fb\u9176\u7684superfamily\u3002 UGT\u8ca0\u8cac\u7d55\u5927\u591a\u6578\u7684II\u671fbiotransformation\u751f\u7269\u8f49\u5316\uff08\u7db4\u5408\uff09\u53cd\u61c9\uff0c\u5176\u4e2d\u89aa\u6c34\u90e8\u5206\u9023\u63a5\u5230\u5c0f\u5206\u5b50\u85e5\u7269\u548c\u5176\u5b83\u7570\u751f\u7269\u8cea\u4e0a\uff0c\u4ee5\u4fc3\u9032\u5b83\u5011\u5f9e\u9ad4\u5167\u5feb\u901f\u6392\u6cc4\u3002 UGT\u4e3b\u8981\u5728\u809d\uff0c\u8178\u548c\u814e\u4e2d\u8868\u9054\uff0c\u5176\u4e2d\u5b83\u5011\u50ac\u5316\u5f9e\u6838\u82f7\u9178\u7cd6\u5c3f\u82f7-5&#8242;-\u4e8c\u78f7\u9178-\u03b1-D-\u8461\u91a3\u919b\u9178\uff08UDPGA\uff09\u5411\u89aa\u6838\u7fa5\u57fa\uff0c\u5df0\u57fa\u6216\u6c28\u57fa\u6dfb\u52a0\u8461\u91a3\u919b\u9178\u90e8\u5206\u7684\u85e5\u7406\u6d3b\u6027\u85e5\u7269\uff0cI\u671f\u85e5\u7269\u4ee3\u8b1d\u7269\u548c\u67d0\u4e9b\u5167\u6e90\u6027\u5e95\u7269\u5982\u985e\u56fa\u9187\u6fc0\u7d20\uff0c\u81bd\u6c41\u9178\u548c\u81bd\u7d05\u7d20\u3002 UGT\u5bb6\u65cf\u7684\u540c\u5de5\u9176\u5177\u6709\u6975\u5bec\uff0c\u901a\u5e38\u91cd\u758a\u7684\u5e95\u7269\u7279\u7570\u6027\uff0c\u4e26\u50be\u5411\u65bc\u5c0d\u5e95\u7269\u986f\u793a\u9069\u5ea6\u7684\u89aa\u548c\u529b\uff0c\u4f46\u662f\u5177\u6709\u9ad8\u50ac\u5316\u8f49\u63db\u7387\u3002 UGT\u9084\u6709\u52a9\u65bc\u201cfirst-pass\u9996\u904e\u201d\u524d\u7cfb\u7d71\u85e5\u7269\u4ee3\u8b1d\uff0c\u5176\u986f\u8457\u964d\u4f4e\u8a31\u591a\u85e5\u7269\u7684\u53e3\u670d\u751f\u7269\u5229\u7528\u5ea6\u3002 BioVision\u7684UGT\u6d3b\u6027\u6e2c\u5b9a\/\u914d\u9ad4\u7be9\u9078\u8a66\u5291\u76d2\u80fd\u5920\u5feb\u901f\u6e2c\u5b9a\u751f\u7269\u6a23\u54c1\u4e2d\u7684\u5929\u7136\u6216\u91cd\u7d44UGT\u6d3b\u6027\uff0c\u5982\u809d\u5fae\u7c92\u9ad4\uff0c\u4e5f\u53ef\u7528\u65bc\u8a55\u4f30\u85e5\u7269\u548c\u5176\u4ed6\u65b0\u5316\u5408\u7269\u5c0dUGT\u6d3b\u6027\u7684\u5f71\u97ff\u3002<\/p>\n<p><strong>\u85e5\u7269\u4ee3\u8b1d\u4ecb\u7d39<\/strong>: \u751f\u7269\u9ad4\u5167\u85e5\u7269\u6216\u7570\u751f\u7269\uff08\u4efb\u4f55\u5916\u4f86\u5316\u5b78\u54c1\uff09\u7684\u4f48\u7f6e\u5305\u62ec\u5206\u5b50\u7684\u5438\u6536\u3001\u5206\u4f48\u3001\u4ee3\u8b1d\u548c\u6392\u6cc4\uff08ADME\uff09\u7684\u6240\u6709\u53cd\u61c9\/\u751f\u7406\u6a5f\u5236\u3002ADME\u5f71\u97ff\u66b4\u9732\u65bc\u7d44\u7e54\u7684\u6fc3\u5ea6\u548c\u52d5\u529b\u5b78\uff0c\u56e0\u6b64\u6c7a\u5b9a\u4e86\u7d66\u5b9a\u5316\u5408\u7269\u7684\u4f5c\u7528\u3002\u4efb\u4f55\u5316\u5b78\u7269\u53ef\u4ee5\u901a\u904e\u5404\u7a2e\u751f\u7269\u5316\u5b78\u4fee\u98fe\u5982\u6c27\u5316\u9084\u539f\u3001\u6c34\u89e3\u3001\u6c34\u5408\u3001\u7db4\u5408\u3001\u7e2e\u5408\u6216\u7570\u69cb\u5316\u4f86\u4ee3\u8b1d\uff0c\u76ee\u7684\u662f\u4f7f\u5206\u5b50\u66f4\u89aa\u6c34\u4e26\u56e0\u6b64\u66f4\u5bb9\u6613\u6392\u6cc4\u3002\u5305\u62ec\u7d30\u80de\u8272\u7d20P450\u9176\u3001\u651d\u53d6\u548c\u6d41\u51fa\u8f49\u904b\u86cb\u767d\uff08P-\u7cd6\u86cb\u767d\uff0cMDR\u8f49\u904b\u86cb\u767d\uff09\u3001\u8f49\u79fb\u9176\u548c\u8a31\u591a\u5176\u4ed6\u9176\u7684\u5927\u91cf\u86cb\u767d\u8cea\u5354\u540c\u5de5\u4f5c\u4ee5\u5206\u89e3\u548c\u8655\u7406\u85e5\u7269\/\u5916\u4f86\u5316\u5b78\u7269\u8cea\u5728\u6211\u5011\u7684\u8eab\u9ad4\u4e2d\u3001\u7522\u751f\u671f\u671b\u7684\u6548\u679c\u6216\u6bd2\u6027\u3002BIOVISION\u63d0\u4f9b\u4e00\u7cfb\u5217\u85e5\u7269\u52d5\u529b\u4e4b\u8a66\u5291\u76d2\uff08\u751f\u7269\u5316\u5b78\u54c1\uff0c\u86cb\u767d\u8cea\uff0c\u6297\u9ad4\uff0c\u6aa2\u6e2c\u8a66\u5291\u76d2\uff09\uff0c\u9069\u7528\u65bc\u85e5\u7269\u8a2d\u8a08\uff0c\u85e5\u7269\u4ee3\u8b1d\/\u904b\u8f38\uff0c\u85e5\u7269\u76f8\u4e92\u4f5c\u7528\uff0c\u85e5\u7269\u4ee3\u8b1d\u9176\u548c\u8f49\u904b\u86cb\u767d\u8868\u9054\u7684\u8abf\u7bc0ADM\uff0c\u9776\u86cb\u767d\u7684\u7d50\u69cb\u7b49\u529f\u80fd\u95dc\u4fc2\u7b49\u5546\u54c1\u3002<\/p>\n<p><strong>\u4ee3\u8b1d\u76f8\u95dc\u5546\u54c1<\/strong><\/p>\n<p>\u78b3\u6c34\u5316\u5408\u7269\u548c\u8102\u8cea\u4ee3\u8b1d | \u80fa\u57fa\u9178\u8207\u7121\u6a5f\u96e2\u5b50\u4ee3\u8b1d | \u7cd6\u9175\u89e3\u9014\u5f91\u548c\u4e2d\u4ecb\u4ee3\u8b1d |\u6c27\u5316\u50b7\u5bb3\u8207\u8840\u6e05\u6210\u5206\u5206\u6790\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.biovision.com\/media\/catalog\/product\/cache\/1\/image\/650x\/040ec09b1e35df139433887a97daa66f\/k\/6\/k692.jpg\" alt=\"\" \/><\/p>\n<table id=\"product-attribute-specs-table\" class=\"data-table\">\n<tbody>\n<tr class=\"first odd\">\n<th class=\"label\">abID<\/th>\n<td class=\"data last\">ab273331<\/td>\n<\/tr>\n<tr class=\"even\">\n<th class=\"label\">Cat # +Size<\/th>\n<td class=\"data last\">K692-100<\/td>\n<\/tr>\n<tr class=\"odd\">\n<th class=\"label\">Size<\/th>\n<td class=\"data last\">100 assays<\/td>\n<\/tr>\n<tr class=\"even\">\n<th class=\"label\">Detection Method<\/th>\n<td class=\"data last\">Fluorescence (Ex\/Em = 415\/502 nm)<\/td>\n<\/tr>\n<tr class=\"odd\">\n<th class=\"label\">Species Reactivity<\/th>\n<td class=\"data last\">Mammalian<\/td>\n<\/tr>\n<tr class=\"even\">\n<th class=\"label\">Applications<\/th>\n<td class=\"data last\">Rapid assessment of native\/recombinant UGT activity in fractions prepared from tissues and cells Screening of drugs and novel ligands for interaction with native\/recombinant UGT enzymes<\/td>\n<\/tr>\n<tr class=\"odd\">\n<th class=\"label\">Features &amp; Benefits<\/th>\n<td class=\"data last\">\u2022 Easy-to-use<br \/>\n\u2022 Non-radioactive<br \/>\n\u2022 Accurately measure UGT activity in microsomes, lysates and recombinant UGT preparations<\/td>\n<\/tr>\n<tr class=\"even\">\n<th class=\"label\">Kit Components<\/th>\n<td class=\"data last\">\u2022 UGT Assay Buffer<br \/>\n\u2022 Inhibitor (Diclofenac)<br \/>\n\u2022 UDPGA Stock (50 X)<br \/>\n\u2022 Alamethicin<br \/>\n\u2022 UGT Substrate (250 X)<br \/>\n\u2022 UGT Positive Control<\/td>\n<\/tr>\n<tr class=\"odd\">\n<th class=\"label\">Storage Conditions<\/th>\n<td class=\"data last\">-20\u00b0C<\/td>\n<\/tr>\n<tr class=\"even\">\n<th class=\"label\">Shipping Conditions<\/th>\n<td class=\"data last\">Gel Pack<\/td>\n<\/tr>\n<tr class=\"last odd\">\n<th class=\"label\">USAGE<\/th>\n<td class=\"data last\">For Research Use Only! Not For Use in Humans.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5546\u54c1: UGT\u5c3f\u82f7\u4e8c\u78f7\u9178 &#8211; \u8461\u91a3\u919b\u9178\u8f49\u79fb\u9176\u87a2\u5149\u5206\u6790\u5957\u7d44 \u00a0| \u8ca8\u865fK692-100\u00a0(Abcam [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":8690,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[498],"tags":[3989],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8709"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8709"}],"version-history":[{"count":4,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8709\/revisions"}],"predecessor-version":[{"id":35655,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8709\/revisions\/35655"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/8690"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8709"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8709"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}