{"id":8030,"date":"2016-12-07T16:00:49","date_gmt":"2016-12-07T08:00:49","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=8030"},"modified":"2022-07-22T16:58:07","modified_gmt":"2022-07-22T08:58:07","slug":"3-methyladenine%e7%b4%b0%e8%83%9e%e8%87%aa%e5%99%ac%e6%8a%91%e5%88%b6%e5%8a%91-%e8%b2%a8%e8%99%9f2249-100","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=8030","title":{"rendered":"3-Methyladenine\u7d30\u80de\u81ea\u566c\u6291\u5236\u5291 | CAS #5142-23-4\u8ca8\u865f2249-100"},"content":{"rendered":"

3-Methyladenine<\/strong>\u7d30\u80de\u81ea\u566c\u6291\u5236\u5291<\/strong> | <\/strong>\u8ca8\u865f<\/strong>2249-100 <\/strong><\/a><\/span>\u00a0<\/strong><\/span>\u00a0A specific autophagy inhibitor<\/p>\n

\u7522\u54c1\u4ecb\u7d39<\/strong>:<\/strong> 3-Methyladenine\uff0c\u901a\u5e38\u7528\u4f5c\u81ea\u566c\u87af\u5408(\u00a0autophagic sequestration) \u7684\u7279\u7570\u6027\u6291\u5236\u5291\u30023-MA\u901a\u904e\u6291\u5236III\u578b\u78f7\u8102\u9170\u808c\u91873-\u6fc0\u9176\uff08Phosphatidylinositol 3-kinases, PI-3K\uff09\u963b\u65b7\u81ea\u566c\u9ad4(autophagosome ) \u5f62\u6210\u4f86\u6291\u5236\u81ea\u566c (autophagy) \u3002\u5206\u5b50\u578b\u5f0fC\u2086H\u2087N\u2085 | \u5206\u5b50\u91cfMolecular Weight: 149.15 | \u7d14\u5ea6Purity: <\/strong>\u226598% by TLC | Solubility: DMSO (50 mM)<\/p>\n

\"\"<\/p>\n

\u7522\u54c1\u63cf\u8ff0<\/strong>:<\/strong> Autophagy\u7d30\u80de\u81ea\u566c\uff0c\u4f5c\u70ba\u7d30\u80dehousekeeper\u6d88\u9664\u6709\u7f3a\u9677\u7684\u86cb\u767d\u8cea\u548c\u7d30\u80de\u5668\uff0c\u4ee5\u9632\u6b62\u7570\u5e38\u86cb\u767d\u805a\u96c6\u7269\u805a\u96c6\uff1b\u548c\u53bb\u9664\u7d30\u80de\u5167\u75c5\u539f\u9ad4\u3002\u9019\u6a23\u7684\u529f\u80fd\u53ef\u80fd\u5c0d\u65bc\u81ea\u566c\u4ecb\u5c0e\u5982\u8001\u5316\u3001\u764c\u75c7\u3001\u795e\u7d93\u8b8a\u6027\u75be\u75c5\u548c\u611f\u67d3\u7684\u4fdd\u8b77\u662f\u95dc\u9375\u7684\u89d2\u8272\u3002\u5b83\u662f\u4e00\u7a2e\u6574\u9ad4\u964d\u89e3\u7cfb\u7d71\uff0c\u5176\u5c07\u7d30\u80de\u8cea\u6210\u5206\u905e\u9001\u5230\u6eb6\u9176\u9ad4\u4e2d\u4e26\u6e05\u9664\u8001\u7684\/\u53d7\u640d\u7684\u7d30\u80de\u5668\uff0c\u9577\u58fd\u86cb\u767d\uff0c\u4e0d\u6eb6\u6027\u86cb\u767d\u8cea\u805a\u96c6\u9ad4\u548c\u8102\u6ef4\u3002\u9019\u4f7f\u5f97\u5728\u98e2\u9913\u671f\u9593\u91cd\u65b0\u4f7f\u7528\u7d30\u80de\u5167\u7d44\u5206\u4f8b\u5982\u6c28\u57fa\u9178\u6c60\uff0c\u4e26\u8abf\u7bc0\u7d30\u80de\u5167\u74b0\u5883\u7a69\u5b9a\uff0c\u7d30\u80de\u6b7b\u4ea1\/\u5b58\u6d3b\u548c\u8102\u8cea\u4ee3\u8b1d\u3002\u81ea\u566c\u53ef\u4ee5\u5206\u70ba\u4e09\u7a2e\u4e3b\u8981\u5f62\u5f0f\uff1amicroautophagy\u5fae\u81ea\u566c\u3001chaperone-mediated autophagy\u3001macroautophagy\u3002BioVision\u63d0\u4f9b\u5ee3\u6cdb\u7684\u81ea\u566c\u8a98\u5c0e\u5291\u548c\u6291\u5236\u5291\u4ee5\u53ca\u6297\u81ea\u566c\u76f8\u95dc\u86cb\u767d\u7684\u6297\u9ad4\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Alternate Name<\/th>\n3-Methyl-3H-purin-6-amine; 3-MA; NSC 66389<\/td>\n<\/tr>\n
Appearance<\/th>\nWhite solid<\/td>\n<\/tr>\n
CAS #<\/th>\n5142-23-4<\/td>\n<\/tr>\n
Molecular Formula<\/th>\nC\u2086H\u2087N\u2085<\/td>\n<\/tr>\n
Molecular Weight<\/th>\n149.15<\/td>\n<\/tr>\n
Purity<\/th>\n\u226598%<\/td>\n<\/tr>\n
Solubility<\/th>\nDMSO (50 mM)<\/td>\n<\/tr>\n
SMILES<\/th>\nCN1C=NC(=C2C1=NC=N2)N<\/td>\n<\/tr>\n
InChi<\/th>\nInChI=1S\/C6H7N5\/c1-11-3-10-5(7)4-6(11)9-2-8-4\/h2-3H,7H2,1H3<\/td>\n<\/tr>\n
InChi Key<\/th>\nFSASIHFSFGAIJM-UHFFFAOYSA-N<\/td>\n<\/tr>\n
PubChem CID<\/th>\n1673<\/a><\/td>\n<\/tr>\n
MDL Number<\/th>\nMFCD00010531<\/td>\n<\/tr>\n
Handling<\/th>\nProtect from light and moisture<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u66f4\u591a\u76f8\u95dc\u5546\u54c1\u00a0<\/span>Autophagy \u81ea\u566c\u6291\u5236\u5291<\/a> | Autophagy\u81ea\u566c\u76f8\u95dc\u6297\u9ad4<\/a> | Autophagy\u81ea\u566c\u8a98\u5c0e\u5291<\/a><\/span><\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u00a0Catalog #<\/a><\/td>\n\u00a0Product Name+<\/a><\/td>\n\u00a0Size<\/a><\/td>\n<\/tr>\n
\u00a02249-25<\/td>\n\u00a03-Methyladenine<\/a><\/strong><\/td>\n\u00a025 mg<\/td>\n<\/tr>\n
\u00a02249-100<\/td>\n\u00a03-Methyladenine<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a01685-5<\/td>\n\u00a0ATM Kinase Inhibitor, KU-55933<\/a><\/strong><\/td>\n\u00a05 mg<\/td>\n<\/tr>\n
\u00a01829-50<\/td>\n\u00a0Bafilomycin A1<\/a><\/strong><\/td>\n\u00a050 \u00b5g<\/td>\n<\/tr>\n
\u00a01829-250<\/td>\n\u00a0Bafilomycin A1<\/a><\/strong><\/td>\n\u00a0250 \u00b5g<\/td>\n<\/tr>\n
\u00a01825-100<\/td>\n\u00a0Chloroquine Diphosphate<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a01825-500<\/td>\n\u00a0Chloroquine Diphosphate<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a01785-500<\/td>\n\u00a0EZSolution\u2122 G\u00f6 6976<\/a><\/strong><\/td>\n\u00a0500 \u00b5g<\/td>\n<\/tr>\n
\u00a01711-500<\/td>\n\u00a0G\u00f6 6976<\/a><\/strong><\/td>\n\u00a0500 \u00b5g<\/td>\n<\/tr>\n
\u00a09419-5<\/td>\n\u00a0MHY1485<\/a><\/strong><\/td>\n\u00a05 mg<\/td>\n<\/tr>\n
\u00a09419-25<\/td>\n\u00a0MHY1485<\/a><\/strong><\/td>\n\u00a025 mg<\/td>\n<\/tr>\n
\u00a0B1286-5<\/td>\n\u00a0SAR-405\u00a0<\/a><\/strong><\/td>\n\u00a05 mg<\/td>\n<\/tr>\n
\u00a0B1286-25<\/td>\n\u00a0SAR-405\u00a0<\/a><\/strong><\/td>\n\u00a025 mg<\/td>\n<\/tr>\n
\u00a02037-5<\/td>\n\u00a0Spautin-1<\/a><\/strong><\/td>\n\u00a05 mg<\/td>\n<\/tr>\n
\u00a02037-25<\/td>\n\u00a0Spautin-1<\/a><\/strong><\/td>\n\u00a025 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

3-Methyladenine\u7d30\u80de\u81ea\u566c\u6291\u5236\u5291 | \u8ca8\u865f2249-100 \u00a0\u00a0A specific autoph […]<\/p>\n","protected":false},"author":3,"featured_media":8027,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486],"tags":[4116],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8030"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8030"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8030\/revisions"}],"predecessor-version":[{"id":32542,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/8030\/revisions\/32542"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/8027"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8030"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8030"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8030"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}