{"id":7815,"date":"2016-11-21T12:12:23","date_gmt":"2016-11-21T04:12:23","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=7815"},"modified":"2022-07-25T11:33:12","modified_gmt":"2022-07-25T03:33:12","slug":"alphapd-l1%e6%8a%97%e9%ab%94-absoluted-antibody-%e8%b2%a8%e8%99%9fab00377-23-0","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=7815","title":{"rendered":"alphaPD-L1\u6297\u9ad4 | Absoluted Antibody \u8ca8\u865fAb00377-23.0"},"content":{"rendered":"

Fc Silent\u2122 Antibodies: Turning down the background noise<\/strong><\/p>\n

Fc Silent| <\/strong>\u6297\u9ad4<\/strong> | <\/strong>\u53ea\u8981<\/strong>\u8a0a<\/strong>\u865f\u4e0d\u8981\u96dc<\/strong>\u8a0a (Engineered Fc Domain)<\/strong><\/p>\n

Absoluted Antibody \u63d0\u4f9b\u4e00\u7cfb\u5217\u6297\u9ad4\u5546\u54c1\uff0c\u5176\u4e2dFc Silent\u2122 Antibodies\u7cfb\u5217\uff1b\u80fd\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027Fc\u7d50\u5408\u3002Fc Silent\u2122\u6280\u8853\uff0c\u70ba\u61c9\u7528\u751f\u7269\u5de5\u7a0b\u6280\u8853\uff0c\u5c07Fc receptors (Fc\u03b3R, FcR)\u9ede\u7a81\u8b8a\uff0c\u9032\u800c\u4e2d\u6b62\u6297\u9ad4\u8207ADCC\u7684\u529f\u80fd\uff1b\u6709\u6548\u964d\u4f4eFc\u6240\u9020\u6210\u7684\u80cc\u666f\u8a0a\u865f\u3002Fc Silent\u2122\u6297\u9ad4\u61c9\u7528\u65bc\u514d\u75ab\u7d30\u80de\u6642flow cytometry\u3001immunohistochemistry (IHC)\u8cc7\u6599\u986f\u793a\uff0c\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027\u4e4bFc\u7d50\u5408\uff0c\u6240\u9020\u6210\u7684\u80cc\u666f\u503c\u3002(\u8a02\u8cfc\u6297\u9ad4\u524d\uff0c\u8acb\u78ba\u8a8d\u9078\u64c7\u6297\u9ad4\u662f\u5426\u6709Fc Silent\u2122\u4fee\u98fe\u6a19\u8a8c)<\/p>\n

\"\"<\/p>\n

\u00a0PD-L1\u6297\u9ad4Anti- PD-L1.\u6297\u9ad4 | \u8ca8\u865fAb00377-23.0<\/strong><\/p>\n

Species and Isotype:<\/strong>\u00a0Rabbit IgG, lambda
\nClone Number:<\/strong>\u00a0alphaPD-L1
\nUniProt Accession Number of Target Protein:\u00a0<\/strong>Q9EP73
\nAlternative Name(s) of Target:\u00a0Programmed Cell Death Ligand 1
\nPublished Application(s):\u00a0ELISA; Blocking
\nPublished Species Reactivity:\u00a0Mouse
\nImmunogen:\u00a0Mouse recombinant PD-L1.
\nSpecificity:\u00a0The antibody binds to murine PD-L1 with a Kd of 0.71 nM.
\nApplication Notes:\u00a0The antibody binds to PD-L1, a costimulatory signal protein necessary for T-cell proliferation.
\nAntibody First Published in:
\nDrees et al. Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coli. Protein Expression and Purification, 2014; 94:60-66\u00a0PMID:24215864<\/a><\/p>\n\n\n\n\n\n\n\n\n
Product<\/a><\/strong><\/td>\nExpected Species Reactivity<\/a><\/strong><\/td>\nIsotype\/Format<\/a><\/strong><\/td>\nModification<\/a><\/strong><\/td>\nProducts<\/a><\/strong><\/td>\n<\/tr>\n<\/thead>\n
Ab00377-1.1 Anti-PDL1 [alphaPD-L1]<\/a><\/td>\nMouse<\/td>\nMouse IgG1<\/td>\n<\/td>\nPurified<\/a><\/td>\n<\/tr>\n
Ab00377-1.4 Anti-PDL1 [alphaPD-L1]<\/a><\/td>\nMouse<\/td>\nMouse IgG1<\/td>\nFc Silent\u2122<\/a><\/td>\nPurified<\/a><\/td>\n<\/tr>\n
Ab00377-23.0 Anti-PDL1 [alphaPD-L1]<\/a><\/td>\nMouse<\/td>\nRabbit IgG<\/td>\n<\/td>\nPurified<\/a><\/td>\n<\/tr>\n
Ab00377-1.7 Anti-PDL1 [alphaPD-L1]<\/a><\/td>\nMouse<\/td>\nMouse F(ab’)2<\/td>\nAbFab2\u2122<\/a><\/td>\nPurified<\/a>Purified<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Fc Silent\u2122 Antibodies: Turning down the background nois […]<\/p>\n","protected":false},"author":3,"featured_media":6981,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[4174],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7815"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7815"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7815\/revisions"}],"predecessor-version":[{"id":7816,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7815\/revisions\/7816"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6981"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7815"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}