{"id":7690,"date":"2016-11-14T17:33:21","date_gmt":"2016-11-14T09:33:21","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=7690"},"modified":"2022-07-25T11:36:34","modified_gmt":"2022-07-25T03:36:34","slug":"%e5%81%87%e6%80%a7%e7%8b%82%e7%8a%ac%e7%97%85%e6%8a%97%e9%ab%94-anti-glycoprotein-h%e8%b2%a8%e8%99%9fab00772","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=7690","title":{"rendered":"\u5047\u6027\u72c2\u72ac\u75c5\u6297\u9ad4 | Anti-Glycoprotein H\u8ca8\u865fAb00772"},"content":{"rendered":"<p><strong>Fc Silent\u2122 Antibodies: Turning down the background noise<\/strong><\/p>\n<p><strong>Fc Silent| <\/strong><strong>\u6297\u9ad4<\/strong><strong> | <\/strong><strong>\u53ea\u8981<\/strong><strong>\u8a0a<\/strong><strong>\u865f\u4e0d\u8981\u96dc<\/strong><strong>\u8a0a (Engineered Fc Domain)<\/strong><\/p>\n<p>Absoluted Antibody \u63d0\u4f9b\u4e00\u7cfb\u5217\u6297\u9ad4\u5546\u54c1\uff0c\u5176\u4e2dFc Silent\u2122 Antibodies\u7cfb\u5217\uff1b\u80fd\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027Fc\u7d50\u5408\u3002Fc Silent\u2122\u6280\u8853\uff0c\u70ba\u61c9\u7528\u751f\u7269\u5de5\u7a0b\u6280\u8853\uff0c\u5c07Fc receptors (Fc\u03b3R, FcR)\u9ede\u7a81\u8b8a\uff0c\u9032\u800c\u4e2d\u6b62\u6297\u9ad4\u8207ADCC\u7684\u529f\u80fd\uff1b\u6709\u6548\u964d\u4f4eFc\u6240\u9020\u6210\u7684\u80cc\u666f\u8a0a\u865f\u3002Fc Silent\u2122\u6297\u9ad4\u61c9\u7528\u65bc\u514d\u75ab\u7d30\u80de\u6642flow cytometry\u3001immunohistochemistry (IHC)\u8cc7\u6599\u986f\u793a\uff0c\u6709\u6548\u964d\u4f4e\u975e\u7279\u7570\u6027\u4e4bFc\u7d50\u5408\uff0c\u6240\u9020\u6210\u7684\u80cc\u666f\u503c\u3002(\u8a02\u8cfc\u6297\u9ad4\u524d\uff0c\u8acb\u78ba\u8a8d\u9078\u64c7\u6297\u9ad4\u662f\u5426\u6709Fc Silent\u2122\u4fee\u98fe\u6a19\u8a8c)<\/p>\n<p>\u7522\u54c1\u4ecb\u7d39 \u5047\u6027\u72c2\u72ac\u75c5\u6297\u9ad4Anti-Glycoprotein H [A13-d6.3] \u6297\u9ad4 | \u7522\u54c1\u63cf\u8ff0:<\/p>\n<p><strong>Description:<\/strong><strong>\u00a0<\/strong>Recombinant monoclonal antibody to Glycoprotein H. Manufactured using AbAb\u2019s Recombinant Platform with variable regions (i.e. specificity) from the hybdridoma A13-d6.3.<br \/>\n<strong>UniProt Accession Number of Target Protein:<\/strong><strong>\u00a0<\/strong>A0A142I9U7<br \/>\n<strong>Alternative Name(s) of Target:<\/strong><strong>\u00a0<\/strong>d6.3; gH; Envelope glycoprotein H\u00a0<strong>Immunogen:<\/strong><strong>\u00a0<\/strong>d6.3 was generated by immunizing mice with PrV.<br \/>\n<strong>Specificity:<\/strong><strong>\u00a0<\/strong>d6.3 Fab fragment binds to the core fragment of the PrV glycoprotein H (gH) ectodomain (aa 107\u2013639) which is the membrane-proximal end of the protein in the ?gL-Pass PrV variant of PrV. The antibody contacts residues 332-373 (peripheral helices \u03b16 and \u03b17 of domain III of gH contribute most of the residues that form the epitope recognized by d6.3). PrV is a porcine herpesvirus belonging to the alpha-Herpesvirinae subfamily and is known to cause Aukeszky&#8217;s disease in pigs. gH is a type I membrane portein and can interact non-covalently with gL via the large gH ectodomain.<\/p>\n<table width=\"100%\">\n<thead>\n<tr>\n<td><strong><a href=\"http:\/\/absoluteantibody.com\/catalog\/primary-antibodies\/?wpv_post_search=RABIES&amp;wpv_filter_submit=Antibody+Search\">Product Name page<\/a><\/strong><\/td>\n<td><strong><a href=\"http:\/\/absoluteantibody.com\/catalog\/primary-antibodies\/?wpv_post_search=RABIES&amp;wpv_filter_submit=Antibody+Search\" data-viewnumber=\"4146-TCPID1993\" data-orderby=\"types-field-expectedspeciesreactivity\" data-order=\"asc\" data-orderbyas=\"\">Expected Species Reactivity<\/a><\/strong><\/td>\n<td><strong><a href=\"http:\/\/absoluteantibody.com\/catalog\/primary-antibodies\/?wpv_post_search=RABIES&amp;wpv_filter_submit=Antibody+Search\" data-viewnumber=\"4146-TCPID1993\" data-orderby=\"types-field-applicationcodesclone\" data-order=\"asc\" data-orderbyas=\"\">Applications<\/a><\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Glycoprotein-H-A13-d6-3\/\">Anti-Glycoprotein H [A13-d6.3]<\/a><\/td>\n<td>pseudorabies virus (PrV)<\/td>\n<td>neutralize; crystalize; immunostaining<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Rabies-Virus-67kDa-protein-EP5G3\/\">Anti-Rabies Virus 67kDa protein [EP5G3]<\/a><\/td>\n<td>Rabies Virus<\/td>\n<td>WB; NTRL; IP; ELISA<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Rabies-Virus-67kDa-protein-Fab094\/\">Anti-Rabies Virus 67kDa protein [Fab094]<\/a><\/td>\n<td>Rabies Virus<\/td>\n<td>WB; NTRL; ELISA; IP<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Rabies-Virus-67kDa-protein-GD2D12\/\">Anti-Rabies Virus 67kDa protein [GD2D12]<\/a><\/td>\n<td>Rabies Virus<\/td>\n<td>WB; NTRL; IP; ELISA<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table style=\"height: 944px;\" width=\"1205\">\n<tbody>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Flavivirus-group-antigen-D1-4G2-4-15-4G2\/\">Anti-Flavivirus group antigen [D1-4G2-4-15 (4G2)]<\/a><\/td>\n<td>Dengue Virus; Zika Virus; West Nile Virus; Flaviviridae<\/td>\n<td>IF; WB; NTRL; ELISA; FC<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-Ebola-Nucleoprotein-KZ51\/\">Anti-Ebola Nucleoprotein [KZ51]<\/a><\/td>\n<td>Ebola Virus (Zaire, Ivory Coast, Reston, Sudan)<\/td>\n<td>ELISA; WB; IP; IF<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-E2-A-domain-F5\/\">Anti-E2 A domain [F5]<\/a><\/td>\n<td>Human Venezuelan Equine Encephalitis Virus<\/td>\n<td>NTRL; crystallization<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-E-protein-DIII-C-C-ZV-64\/\">Anti-E-protein DIII (C-C\u2019) [ZV-64]<\/a><\/td>\n<td>Zika Virus<\/td>\n<td>NTRL; crystallization; SPR; FC<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-dsRNA-10G1\/\">Anti-dsRNA [10G1]<\/a><\/td>\n<td>Virus<\/td>\n<td>ELISA; IHC; WB<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-DIII-domain-of-Dengue-E-protein-DV10\/\">Anti-DIII domain of Dengue E protein [DV10]<\/a><\/td>\n<td>Dengue Virus<\/td>\n<td>ELISA; NTRL<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-DIII-domain-of-Dengue-E-protein-DENV-1-and-DENV-3-DV63\/\">Anti-DIII domain of Dengue E protein (DENV-1 and DENV-3) [DV63]<\/a><\/td>\n<td>Dengue Virus<\/td>\n<td>ELISA; NTRL<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-DIDII-domain-of-Dengue-E-protein-DV18\/\">Anti-DI\/DII domain of Dengue E protein [DV18]<\/a><\/td>\n<td>Dengue Virus<\/td>\n<td>ELISA; NTRL<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-CytomegaloVirus-CMV-gH-glycoprotein-MSL-109\/\">Anti-CytomegaloVirus (CMV) gH glycoprotein [MSL-109]<\/a><\/td>\n<td>CMV<\/td>\n<td>NTRL<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-CPV-capsid-14\/\">Anti-CPV capsid [14]<\/a><\/td>\n<td>canine parovirus (CPV)<\/td>\n<td>neutralize; crystallize; cryoEM<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-CMV-glycoprotein-gB-HCMV37\/\">Anti-CMV glycoprotein gB [HCMV37]<\/a><\/td>\n<td>CMV<\/td>\n<td>NTRL; ELISA; IHC-Fr; IF; ICC<\/td>\n<\/tr>\n<tr>\n<td><a href=\"http:\/\/absoluteantibody.com\/ab\/Anti-A14-BB5-2\/\">Anti-A14 [BB5.2]<\/a><\/td>\n<td>Vaccinia virus<\/td>\n<td>WB; IP; IF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Fc Silent\u2122 Antibodies: Turning down the background nois [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":6231,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[136],"tags":[4202],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7690"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7690"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7690\/revisions"}],"predecessor-version":[{"id":7692,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/7690\/revisions\/7692"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6231"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7690"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}