{"id":6908,"date":"2016-10-01T00:08:58","date_gmt":"2016-09-30T16:08:58","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=6908"},"modified":"2022-07-25T17:30:14","modified_gmt":"2022-07-25T09:30:14","slug":"6-aminonicotinamide%e6%8a%91%e5%88%b6%e5%8a%91-glycolysis-inhibitors-%e8%b2%a8%e8%99%9fb1047-500","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=6908","title":{"rendered":"6-Aminonicotinamide\u6291\u5236\u5291 |Glycolysis Inhibitors \u8ca8\u865fB1047-500"},"content":{"rendered":"

\"New\u00a0:\u00a02-Deoxy-D-Glucose\"Glycolysis Inhibitors\u6291\u5236\u5291 | 6-Aminonicotinamide\u6291\u5236\u5291 | Biovision\u8ca8\u865fB1047-500<\/p>\n

A hexokinase inhibitor that has been shown to abolish ATP production and cause severe depletion of cellular ATP.<\/p>\n

\"6-Aminonicotinamide\"<\/a><\/p>\n

Glycolysis Inhibitors\u7cfb\u5217\u5546\u54c1\u4ecb\u7d39: Glycolysis Inhibitors<\/b><\/a><\/p>\n

\u6240\u6709\u764c\u75c7\u548c\u816b\u7624\u7684\u7279\u6027\uff0c\u70ba\u4e0a\u8abf\u7cd6\u9175\u89e3\u4f5c\u7528\u589e\u52a0\u8461\u8404\u7cd6\u6d88\u8017\uff0c\u4ee3\u8b1d\u9014\u5f91\u7522\u751fATP\u3002\u9019\u7a2e\u73fe\u8c61\u88ab\u7a31\u70ba\u74e6\u6c0f\uff08Warburg\u2019s effect\uff09\uff1b\u4ea6\u662f\u60e1\u6027\u671f\u9593\u4ee3\u8b1d\u6539\u8b8a\u7684\u4e00\u500b\u91cd\u8981\u904e\u7a0b\u3002\u8a31\u591a\u751f\u5316\u548c\u5206\u5b50\u751f\u7269\u5b78\u7814\u7a76\u5df2\u7d93\u63d0\u51fa\u4e86\u9019\u500b\u6a5f\u5236\u7684\u6539\u8b8a\uff0c\u5305\u62ec\u7dda\u7c92\u9ad4\u7f3a\u9677\u548c\u6545\u969c\uff0c\u4ee5\u9069\u61c9\u7f3a\u6c27\u816b\u7624\u5fae\u74b0\u5883\uff1b\u81f4\u764c\u4fe1\u865f\u548c\u4ee3\u8b1d\u9176\u7684\u7570\u5e38\u8868\u9054\u7b49\u3002\u6700\u91cd\u8981\u7684\u662f\u764c\u7d30\u80de\u65bc\u4ee3\u8b1d\u4e0a\uff0c\u5c0d\u7cd6\u9175\u89e3\u9014\u5f91\u7522\u751f\u7684ATP\u5177\u6709\u4f9d\u8cf4\u6027\u3002\u8a31\u591a\u5c0f\u5206\u5b50\u5df2\u7d93\u51fa\u73fe\u986f\u793a\u6709\u5e0c\u671b\u6297\u764c\u6d3b\u6027\uff0c\u4f5c\u70ba\u8207\u5176\u4ed6\u6cbb\u7642\u5f62\u5f0f\u7d44\u5408\u4e4b\u55ae\u4e00\u85e5\u5291\u3002\u7cd6\u9175\u89e3\u6291\u5236\u5291\uff0c\u56e0\u6b64\u4f5c\u70ba\u6297\u764c\u85e5\u7269\u7684\u767c\u5c55\u5fc5\u5c07\u5177\u6709\u5ee3\u95ca\u7684\u6cbb\u7642\u61c9\u7528\uff0c\u4e5f\u53ef\u671d\u5411\u8207\u5e38\u898f\u85e5\u7269\u548c\u653e\u5c04\u6cbb\u7642\u7684\u7d30\u80de\u6297\u6027\u76f8\u95dc\u7684\u60e1\u6027\u816b\u7624\u7684\u76ee\u6a19\u3002<\/p>\n

Glycolysis Inhibitors\u6291\u5236\u5291 | 6-Aminonicotinamide\u6291\u5236\u52916-\u6c28\u57fa\u7159\u9170\u80fa\uff086-AN\uff09\u70ba\u6291\u5236\u8461\u8404\u7cd6-6-\u78f7\u9178\u812b\u6c2b\u9176\uff08G6PD\uff09\uff0c\u50ac\u5316G-6-P\u7684\u81f36-\u78f7\u9178\u8461\u7cd6\u9178\u5167\u916f\uff0c\u620a\u7cd6\u78f7\u9178\u9014\u5f91\u7684\u7b2c\u4e00\u500b\u6b65\u9a5f\u7684\u8f49\u63db\u30026-AN\u5df2\u88ab\u5ee3\u6cdb\u5730\u7528\u4f5c\u5728\u7814\u7a76\u6291\u5236\u620a\u7cd6\u78f7\u9178\u9014\u5f91\u3002NADPH\u548c\u91cd\u8981\u7684\u4ee3\u8b1d\u4e2d\u9593\u9ad4\uff08\u620a\u7cd6-5-\u78f7\u9178\uff09\u70ba\u91cd\u8981\u89d2\u8272\uff1b6-AN\u9ad4\u5916\u8868\u73fe\u6297\u764c\u6d3b\u6027\uff0c\u5c0e\u81f4\u6c27\u5316stress\uff0c\u4e26\u654f\u611f\u7d30\u80de\u5c0d\u6297\u764c\u5291\u548c\u8f3b\u5c04\u3002<\/p>\n

Molecular Formula: C\u2086H\u2087N\u2083O<\/p>\n

Molecular Weight: 137.1<\/p>\n

Purity: \u226598% by HPLC<\/p>\n

Solubility: DMSO (~ 1 mg\/ml)<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u00a0Catalog #<\/a><\/td>\n\u00a0Product Name+<\/a><\/td>\n\u00a0Size<\/a><\/td>\n<\/tr>\n
\u00a0B1048-100<\/td>\n\u00a02-Deoxy-D-Glucose\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1048-500<\/td>\n\u00a02-Deoxy-D-Glucose\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1045-100<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1045-500<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1045-1000<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a01 g<\/td>\n<\/tr>\n
\u00a0B1047-100<\/td>\n\u00a06-Aminonicotinamide\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1047-500<\/td>\n\u00a06-Aminonicotinamide\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1058-10<\/td>\n\u00a0Lonidamine\u00a0<\/a><\/strong><\/td>\n\u00a010 mg<\/td>\n<\/tr>\n
\u00a0B1058-50<\/td>\n\u00a0Lonidamine\u00a0<\/a><\/strong><\/td>\n\u00a050 mg<\/td>\n<\/tr>\n
\u00a0B1046-100<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1046-500<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1046-1000<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a01 g<\/td>\n<\/tr>\n
\u00a0B1056-10<\/td>\n\u00a0Shikonin\u00a0<\/a><\/strong><\/td>\n\u00a010 mg<\/td>\n<\/tr>\n
\u00a0B1056-50<\/td>\n\u00a0Shikonin\u00a0<\/a><\/strong><\/td>\n\u00a050 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Glycolysis Inhibitors\u6291\u5236\u5291 | 6-Aminonicotinamide\u6291\u5236\u5291 | Bio […]<\/p>\n","protected":false},"author":3,"featured_media":6898,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486,477,451],"tags":[4398],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6908"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6908"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6908\/revisions"}],"predecessor-version":[{"id":6909,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6908\/revisions\/6909"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6898"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6908"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6908"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}