{"id":6906,"date":"2016-09-30T23:57:00","date_gmt":"2016-09-30T15:57:00","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=6906"},"modified":"2022-07-25T17:30:21","modified_gmt":"2022-07-25T09:30:21","slug":"3-bromopyruvic-acid-glycolysis-inhibitors%e6%8a%91%e5%88%b6%e5%8a%91-biovision%e8%b2%a8%e8%99%9fb1045-1000","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=6906","title":{"rendered":"3-Bromopyruvic acid |Glycolysis Inhibitors\u6291\u5236\u5291 Biovision\u8ca8\u865fB1045-1000"},"content":{"rendered":"

\"New\u00a0:\u00a02-Deoxy-D-Glucose\"Glycolysis Inhibitors\u6291\u5236\u5291 | 3-Bromopyruvic acid\u6291\u5236\u5291 | Biovision\u8ca8\u865fB1045-1000<\/p>\n

Glycolysis Inhibitors<\/b><\/a>\u00a0A hexokinase inhibitor that has been shown to abolish ATP production and cause severe depletion of cellular ATP.<\/p>\n

\"3-Bromopyruvic<\/a><\/p>\n

Glycolysis Inhibitors\u7cfb\u5217\u5546\u54c1\u4ecb\u7d39:<\/p>\n

\u6240\u6709\u764c\u75c7\u548c\u816b\u7624\u7684\u7279\u6027\uff0c\u70ba\u4e0a\u8abf\u7cd6\u9175\u89e3\u4f5c\u7528\u589e\u52a0\u8461\u8404\u7cd6\u6d88\u8017\uff0c\u4ee3\u8b1d\u9014\u5f91\u7522\u751fATP\u3002\u9019\u7a2e\u73fe\u8c61\u88ab\u7a31\u70ba\u74e6\u6c0f\uff08Warburg\u2019s effect\uff09\uff1b\u4ea6\u662f\u60e1\u6027\u671f\u9593\u4ee3\u8b1d\u6539\u8b8a\u7684\u4e00\u500b\u91cd\u8981\u904e\u7a0b\u3002\u8a31\u591a\u751f\u5316\u548c\u5206\u5b50\u751f\u7269\u5b78\u7814\u7a76\u5df2\u7d93\u63d0\u51fa\u4e86\u9019\u500b\u6a5f\u5236\u7684\u6539\u8b8a\uff0c\u5305\u62ec\u7dda\u7c92\u9ad4\u7f3a\u9677\u548c\u6545\u969c\uff0c\u4ee5\u9069\u61c9\u7f3a\u6c27\u816b\u7624\u5fae\u74b0\u5883\uff1b\u81f4\u764c\u4fe1\u865f\u548c\u4ee3\u8b1d\u9176\u7684\u7570\u5e38\u8868\u9054\u7b49\u3002\u6700\u91cd\u8981\u7684\u662f\u764c\u7d30\u80de\u65bc\u4ee3\u8b1d\u4e0a\uff0c\u5c0d\u7cd6\u9175\u89e3\u9014\u5f91\u7522\u751f\u7684ATP\u5177\u6709\u4f9d\u8cf4\u6027\u3002\u8a31\u591a\u5c0f\u5206\u5b50\u5df2\u7d93\u51fa\u73fe\u986f\u793a\u6709\u5e0c\u671b\u6297\u764c\u6d3b\u6027\uff0c\u4f5c\u70ba\u8207\u5176\u4ed6\u6cbb\u7642\u5f62\u5f0f\u7d44\u5408\u4e4b\u55ae\u4e00\u85e5\u5291\u3002\u7cd6\u9175\u89e3\u6291\u5236\u5291\uff0c\u56e0\u6b64\u4f5c\u70ba\u6297\u764c\u85e5\u7269\u7684\u767c\u5c55\u5fc5\u5c07\u5177\u6709\u5ee3\u95ca\u7684\u6cbb\u7642\u61c9\u7528\uff0c\u4e5f\u53ef\u671d\u5411\u8207\u5e38\u898f\u85e5\u7269\u548c\u653e\u5c04\u6cbb\u7642\u7684\u7d30\u80de\u6297\u6027\u76f8\u95dc\u7684\u60e1\u6027\u816b\u7624\u7684\u76ee\u6a19\u3002<\/p>\n

Glycolysis Inhibitors\u6291\u5236\u5291 | 3-Bromopyruvic acid\u6291\u5236\u52913-\u6eb4\u4e19\u916e\u9178(3-Bromopyruvic acid)\u986f\u793a\u4e2d\u6b62ATP\u7522\u751f\uff0c\u4e26\u5c0e\u81f4\u7d30\u80deATP\u7684\u56b4\u91cd\u6d88\u8017\uff0c\u662f\u4e00\u500b\u5df1\u7cd6\u6fc0\u9176\u6291\u5236\u5291(hexokinase inhibitor)\u3002\u986f\u793a\u5c0d\u764c\u7d30\u80de\u5177\u6709\u5728\u7f3a\u6c27\u74b0\u5883\u7dda\u7c92\u9ad4\u547c\u5438\u7f3a\u9677\u548c\u7d30\u80de\u7684\u5f37\u7d30\u80de\u6bd2\u6d3b\u6027\u30023-Bromopyruvic acid is a hexokinase inhibitor that has been shown to abolish ATP production and cause severe depletion of cellular ATP. It displays potent cytotoxic activity against cancer cells with mitochondrial respiratory defects and cells in hypoxic environment<\/p>\n

Molecular Formula: C\u2083H\u2083BrO\u2083<\/p>\n

Molecular Weight: 166.96<\/p>\n

Purity: \u226597% by titration<\/p>\n

Solubility: H2O (>100 mg\/ml) or DMSO<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u00a0Catalog #<\/a><\/td>\n\u00a0Product Name+<\/a><\/td>\n\u00a0Size<\/a><\/td>\n<\/tr>\n
\u00a0B1048-100<\/td>\n\u00a02-Deoxy-D-Glucose\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1048-500<\/td>\n\u00a02-Deoxy-D-Glucose\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1045-100<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1045-500<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1045-1000<\/td>\n\u00a03-Bromopyruvic acid\u00a0<\/a><\/strong><\/td>\n\u00a01 g<\/td>\n<\/tr>\n
\u00a0B1047-100<\/td>\n\u00a06-Aminonicotinamide\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1047-500<\/td>\n\u00a06-Aminonicotinamide\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1058-10<\/td>\n\u00a0Lonidamine\u00a0<\/a><\/strong><\/td>\n\u00a010 mg<\/td>\n<\/tr>\n
\u00a0B1058-50<\/td>\n\u00a0Lonidamine\u00a0<\/a><\/strong><\/td>\n\u00a050 mg<\/td>\n<\/tr>\n
\u00a0B1046-100<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a0100 mg<\/td>\n<\/tr>\n
\u00a0B1046-500<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a0500 mg<\/td>\n<\/tr>\n
\u00a0B1046-1000<\/td>\n\u00a0Oxythiamine Chloride Hydrochloride\u00a0<\/a><\/strong><\/td>\n\u00a01 g<\/td>\n<\/tr>\n
\u00a0B1056-10<\/td>\n\u00a0Shikonin\u00a0<\/a><\/strong><\/td>\n\u00a010 mg<\/td>\n<\/tr>\n
\u00a0B1056-50<\/td>\n\u00a0Shikonin\u00a0<\/a><\/strong><\/td>\n\u00a050 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Glycolysis Inhibitors\u6291\u5236\u5291 | 3-Bromopyruvic acid\u6291\u5236\u5291 | Bio […]<\/p>\n","protected":false},"author":3,"featured_media":6898,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486,477,451],"tags":[4399],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6906"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6906"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6906\/revisions"}],"predecessor-version":[{"id":6907,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6906\/revisions\/6907"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6898"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6906"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}