{"id":6856,"date":"2016-09-27T11:51:19","date_gmt":"2016-09-27T03:51:19","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=6856"},"modified":"2022-07-25T17:31:27","modified_gmt":"2022-07-25T09:31:27","slug":"arn-509%e9%81%b8%e6%93%87%e6%80%a7%e8%88%87%e7%ab%b6%e7%88%ad%e6%80%a7%e4%b9%8bar%e6%8a%91%e5%88%b6%e5%8a%91-biovision%e8%b2%a8%e8%99%9f-9535-25","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=6856","title":{"rendered":"ARN-509\u9078\u64c7\u6027\u8207\u7af6\u722d\u6027\u4e4bAR\u6291\u5236\u5291 | Biovision\u8ca8\u865f: 9535-25"},"content":{"rendered":"<p>Androgen Receptor Antagonists\u6291\u5236\u5291 | ARN-509\u6291\u5236\u5291 | \u8ca8\u865f: 9535-25<\/p>\n<p>A selective and competitive androgen receptor (AR) inhibitor<\/p>\n<p><a class=\"fancybox fancybox.image\" title=\"ARN-509\" href=\"http:\/\/www.biovision.com\/images\/images_big\/9535.gif\"><img decoding=\"async\" loading=\"lazy\" title=\" ARN-509 \" src=\"http:\/\/www.biovision.com\/images\/9535.gif\" alt=\"ARN-509\" width=\"230\" height=\"150\" border=\"0\" hspace=\"5\" vspace=\"5\" \/><\/a><\/p>\n<p>ARN-509\u662f\u4e00\u7a2e\u9078\u64c7\u6027\u7684\u8207\u7af6\u722d\u6027\u4e4b\u96c4\u6fc0\u7d20\u53d7\u9ad4\uff08AR\uff09\u6291\u5236\u5291\uff08IC 50= 16 nM\uff09\u3002ARN-509\u9078\u64c7\u6027\u5730\u7d50\u5408\u96c4\u6fc0\u7d20\u53d7\u9ad4\u548c\u640d\u5bb3\u5176\u6838\u8f49\u4f4d\u53caDNA\u7d50\u5408\u4f5c\u7528\uff0c\u70ba\u524d\u5217\u817a\u764c\u7684\u6cbb\u7642\u4e2d\u6709\u7528\u4e4b\u96c4\u6fc0\u7d20\u53cd\u61c9\u7684\u5143\u7d20\u3002<\/p>\n<p>ARN-509 is a selective and competitive androgen receptor (AR) inhibitor (IC\u2085\u2080 = 16 nM). ARN-509 selectively binds the androgen receptor and impairs its nuclear translocation and DNA binding to androgen response elements useful for prostate cancer treatment.<\/p>\n<p>Molecular Formula: C\u2082\u2081H\u2081\u2085F\u2084N\u2085O\u2082S<\/p>\n<p>Molecular Weight: 477.43<\/p>\n<p>Purity: \u226598% by HPLC<\/p>\n<p>Solubility: DMSO (&gt;5 mg\/ml)<\/p>\n<table width=\"59%\">\n<tbody>\n<tr>\n<td><a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/androgen-receptor-antagonists-3018\/index-1-1a.html\">Catalog #<\/a><\/td>\n<td>\u00a0<a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/androgen-receptor-antagonists-3018\/index-1-2d.html\">Product Name+<\/a><\/td>\n<td>\u00a0<a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/androgen-receptor-antagonists-3018\/index-1-3a.html\">Size<\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a09535-5<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/arn-509-10272.html\">ARN-509<\/a><\/strong><\/td>\n<td>\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09535-25<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/arn-509-10273.html\">ARN-509<\/a><\/strong><\/td>\n<td>\u00a025 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09479-10<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/mdv-3100-10149.html\">MDV-3100<\/a><\/strong><\/td>\n<td>\u00a010 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09479-50<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/mdv-3100-10150.html\">MDV-3100<\/a><\/strong><\/td>\n<td>\u00a050 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09668-5<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/odm-201-10964.html\">ODM-201\u00a0<\/a><\/strong><\/td>\n<td>\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09668-25<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/odm-201-10965.html\">ODM-201\u00a0<\/a><\/strong><\/td>\n<td>\u00a025 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"color: #ff0000;\">\u66f4\u591a\u9175\u7d20\u578b\u6291\u5236\u5291\u5546\u54c1<\/span>: <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6858\">ACE\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6856\">AR\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6849\">AKR\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6846\">adenylyl cyclase \u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6844\">AAC\u6291\u5236\u5291<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6838\">ACAT\u6291\u5236\u5291<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Androgen Receptor Antagonists\u6291\u5236\u5291 | ARN-509\u6291\u5236\u5291 | \u8ca8\u865f: 953 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":6676,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486,451],"tags":[4409],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6856"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6856"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6856\/revisions"}],"predecessor-version":[{"id":6867,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6856\/revisions\/6867"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6676"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6856"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6856"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6856"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}