{"id":6844,"date":"2016-09-27T10:37:06","date_gmt":"2016-09-27T02:37:06","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=6844"},"modified":"2022-07-25T17:31:58","modified_gmt":"2022-07-25T09:31:58","slug":"cp-640186%e6%8a%91%e5%88%b6%e5%8a%91-%e6%b7%b7%e5%90%88%e5%9e%8bacc-inhibitors-biovision%e8%b2%a8%e8%99%9f-9422-25","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=6844","title":{"rendered":"CP-640186\u6291\u5236\u5291 |\u6df7\u5408\u578bACC Inhibitors Biovision\u8ca8\u865f: 9422-25"},"content":{"rendered":"<p>\u6df7\u5408\u578bACC Inhibitors | CP-640186\u6291\u5236\u5291 | \u8ca8\u865f: 9422-25<\/p>\n<p>A mixed ACC (Acetyl-CoA carboxylase) inhibitor<\/p>\n<p><a class=\"fancybox fancybox.image\" title=\"CP-640186\" href=\"http:\/\/www.biovision.com\/images\/images_big\/9422.gif\"><img decoding=\"async\" loading=\"lazy\" title=\" CP-640186 \" src=\"http:\/\/www.biovision.com\/images\/9422.gif\" alt=\"CP-640186\" width=\"230\" height=\"150\" border=\"0\" hspace=\"5\" vspace=\"5\" \/><\/a><\/p>\n<p>CP-640186\u662f\u6df7\u5408\u578bACC\uff08\u4e59\u9170\u8f14\u9176A\u7fa7\u5316\u9176\uff09\u6291\u5236\u5291\uff08ACC-1 IC 50= 53\u7d0d\u7c73; ACC-2 IC 50=61\u7d0d\u7c73\uff09\uff0c\u964d\u4f4emalonyl&#8211;CoA\u6c34\u5e73\uff0c\u5728\u9ad4\u5916\u548c\u9ad4\u5167\u5be6\u9a57\u4e2d\uff0c\u6291\u5236\u809d\u8102\u80aa\u9178\u548c\u7518\u6cb9\u4e09\u916f\u7684\u5408\u6210\uff0c\u4ee5\u53ca\u523a\u6fc0\u808c\u8089\u8102\u80aa\u9178\u6c27\u5316\u53ca\u964d\u4f4e\u5927\u9f20body RQ\u3002CP-640186 is a mixed ACC (Acetyl-CoA carboxylase) inhibitor (ACC-1 IC\u2085\u2080 = 53 nM; ACC-2 IC\u2085\u2080 = 61 nM) that lowers malonyl-CoA levels and inhibits hepatic fatty acid and triglyceride synthesis in vitro and in vivo, as well as stimulates muscle fatty acid oxidation and lowers whole body RQ in rats.<\/p>\n<p>&nbsp;<\/p>\n<p>Molecular Formula: C\u2083\u2080H\u2083\u2085N\u2083O\u2083<\/p>\n<p>Molecular Weight: 485.62<\/p>\n<p>Purity: \u226598% by HPLC<\/p>\n<p>Solubility: DMSO<\/p>\n<table width=\"62%\">\n<tbody>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/acc-inhibitors-2050\/index-1-1a.html\">Catalog #<\/a><\/td>\n<td>\u00a0<a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/acc-inhibitors-2050\/index-1-2d.html\">Product Name+<\/a><\/td>\n<td>\u00a0<a href=\"http:\/\/www.biovision.com\/enzyme-inhibitors-2006\/acc-inhibitors-2050\/index-1-3a.html\">Size<\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a01717-5<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/acc2-inhibitor-10872.html\">ACC2 Inhibitor\u00a0<\/a><\/strong><\/td>\n<td>\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a01717-1<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/acc2-inhibitor-3984.html\">ACC2 Inhibitor<\/a><\/strong><\/td>\n<td>\u00a01 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09422-5<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/cp-640186-9977.html\">CP-640186<\/a><\/strong><\/td>\n<td>\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09422-25<\/td>\n<td>\u00a0<strong><a href=\"http:\/\/www.biovision.com\/cp-640186-9978.html\">CP-640186<\/a><\/strong><\/td>\n<td>\u00a025 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"color: #ff0000;\">\u66f4\u591a\u9175\u7d20\u578b\u6291\u5236\u5291\u5546\u54c1:<\/span> <span style=\"color: #3366ff;\"><a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6858\">ACE\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6856\">AR\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6849\">AKR\u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6846\">adenylyl cyclase \u6291\u5236\u5291\u985e<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6844\">AAC\u6291\u5236\u5291<\/a> | <a style=\"color: #3366ff;\" href=\"http:\/\/biopioneer.com.tw\/?p=6838\">ACAT\u6291\u5236\u5291<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6df7\u5408\u578bACC Inhibitors | CP-640186\u6291\u5236\u5291 | \u8ca8\u865f: 9422-25 A mixed  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":6676,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[486,451],"tags":[4413],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6844"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6844"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6844\/revisions"}],"predecessor-version":[{"id":6873,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6844\/revisions\/6873"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6676"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6844"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6844"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6844"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}