{"id":6358,"date":"2016-09-05T16:08:53","date_gmt":"2016-09-05T08:08:53","guid":{"rendered":"http:\/\/biopioneer.com.tw\/?p=6358"},"modified":"2022-07-26T14:06:32","modified_gmt":"2022-07-26T06:06:32","slug":"sklb610%e8%a1%80%e7%ae%a1%e6%96%b0%e7%94%9f%e6%8a%91%e5%88%b6%e5%8a%91-%e7%99%8c%e7%97%87%e7%9b%b8%e9%97%9c%e5%88%86%e6%9e%90","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=6358","title":{"rendered":"SKLB610\u8840\u7ba1\u65b0\u751f\u6291\u5236\u5291 |\u764c\u75c7\u76f8\u95dc\u5206\u6790"},"content":{"rendered":"<p><strong>\u8840\u7ba1\u65b0\u751f\u6291\u5236\u5291<\/strong><strong>SKLB610<\/strong> \u00a0\u8ca8\u865f2610-25 \u00a0| 25 mg<\/p>\n<p>\u7522\u54c1\u63cf\u8ff0: Biovision\u63d0\u4f9b\u4e00\u7cfb\u5217\u764c\u75c7\u76f8\u95dc\u5206\u6790\u5957\u7d44\uff1b\u5305\u62ec\u8840\u7ba1\u65b0\u751f\u3001\u7d30\u80de\u4fb5\u5165Invasion\u3001\u7d30\u80de\u9077\u79fbmigration\u3001\u6297\u764c\u85e5\u5291\u3001\u6297\u764c\u86cb\u767d\u3001\u764c\u75c7\u884c\u70ba\u5206\u6790\u7b49\u5206\u6790\u5546\u54c1\u3002\u5176\u4e2d\u8840\u7ba1\u65b0\u751f\u6291\u5236\u5291SKLB610\uff0c\u70baVEGFR\u6291\u5236\u5291\uff0c\u6709\u6548\u5730\u6291\u5236\u816b\u7624\u8840\u7ba1\u65b0\u751f\u3002\u8840\u7ba1\u65b0\u751f(Angogenesis)\uff0c\u662f\u6307\u764c\u75c7\u751f\u9577\u548c\u5f62\u6210\u7684\u65b0\u8840\u7ba1\u751f\u6210\u904e\u7a0b\u3002\u8840\u7ba1\u65b0\u751f\u662f\u816b\u7624\u60e1\u5316\u904e\u7a0b\u4e2d\u6c7a\u5b9a\u6027\u56e0\u7d20\uff0c\u5305\u62ec\u816b\u7624\u7684\u5316\u5b78\u4fe1\u865f\u8abf\u7bc0\u8840\u7ba1\u751f\u6210\uff0c\u4fc3\u9032\u8840\u6db2\u4f9b\u61c9\u589e\u52a0\uff0c\u53ca\u6c27\u6c23\u7684\u816b\u7624\u5fae\u74b0\u5883\u3002\u8840\u7ba1\u65b0\u751f\u7642\u6cd5\u4f9d\u64da\u3010\u816b\u7624\u6709\u8840\u7ba1\u65b0\u751f\u4f9d\u8cf4\u6027\u3011\uff0c\u4f7f\u7528\u67d0\u4e9b\u5316\u5408\u7269\uff0c\u6291\u5236\u6216\u5f15\u8d77\u65b0\u7684\u8840\u7ba1\u751f\u9577\uff0c\u4ee5\u9054\u5230\u63a7\u5236\u67d0\u4e9b\u75be\u75c5\u7684\u7642\u6cd5\u3002<\/p>\n<p>SKLB610 | CAS # 1125780-41-7 | BioVision Inc.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" title=\" SKLB610 \" src=\"http:\/\/www.biovision.com\/images\/2610.gif\" alt=\"SKLB610\" width=\"230\" height=\"150\" border=\"0\" hspace=\"5\" vspace=\"5\" \/><script src=\"\/\/connect.facebook.net\/en_US\/fbds.js\" async=\"\"><\/script><script src=\"\/\/www.google-analytics.com\/analytics.js\" async=\"\"><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\nvar form = \"\";\nvar submitted = false;\nvar error = false;\nvar error_message = \"\";\n\nfunction check_input(field_name, field_size, message) {\n  if (form.elements[field_name] &#038;&#038; (form.elements[field_name].type != \"hidden\")) {\n    var field_value = form.elements[field_name].value;\n\n\/\/ LINE MOD: added 'field_size >0 &&'\n    if ((field_size > 0 && field_value == '') || field_value.length < field_size) {\n      error_message = error_message + \"* \" + message + \"\\n\";\n      error = true;\n    }\n  }\n}\n\nfunction check_radio(field_name, message) {\n  var isChecked = false;\n\n  if (form.elements[field_name] &#038;&#038; (form.elements[field_name].type != \"hidden\")) {\n    var radio = form.elements[field_name];\n\n    for (var i=0; i<radio.length; i++) {\n      if (radio[i].checked == true) {\n        isChecked = true;\n        break;\n      }\n    }\n\n    if (isChecked == false) {\n      error_message = error_message + \"* \" + message + \"\\n\";\n      error = true;\n    }\n  }\n}\n\nfunction check_select(field_name, field_default, message) {\n  if (form.elements[field_name] &#038;&#038; (form.elements[field_name].type != \"hidden\")) {\n    var field_value = form.elements[field_name].value;\n\n    if (field_value == field_default) {\n      error_message = error_message + \"* \" + message + \"\\n\";\n      error = true;\n    }\n  }\n}\n\nfunction check_password(field_name_1, field_name_2, field_size, message_1, message_2) {\n  if (form.elements[field_name_1] &#038;&#038; (form.elements[field_name_1].type != \"hidden\")) {\n    var password = form.elements[field_name_1].value;\n    var confirmation = form.elements[field_name_2].value;\n\n    if (password == '' || password.length < field_size) {\n      error_message = error_message + \"* \" + message_1 + \"\\n\";\n      error = true;\n    } else if (password != confirmation) {\n      error_message = error_message + \"* \" + message_2 + \"\\n\";\n      error = true;\n    }\n  }\n}\n\nfunction check_password_new(field_name_1, field_name_2, field_name_3, field_size, message_1, message_2, message_3) {\n  if (form.elements[field_name_1] &#038;&#038; (form.elements[field_name_1].type != \"hidden\")) {\n    var password_current = form.elements[field_name_1].value;\n    var password_new = form.elements[field_name_2].value;\n    var password_confirmation = form.elements[field_name_3].value;\n\n    if (password_current == '' || password_current.length < field_size) {\n      error_message = error_message + \"* \" + message_1 + \"\\n\";\n      error = true;\n    } else if (password_new == '' || password_new.length < field_size) {\n      error_message = error_message + \"* \" + message_2 + \"\\n\";\n      error = true;\n    } else if (password_new != password_confirmation) {\n      error_message = error_message + \"* \" + message_3 + \"\\n\";\n      error = true;\n    }\n  }\n}\n\nfunction check_form(form_name) {\n  if (submitted == true) {\n    alert(\"This form has already been submitted. Please press Ok and wait for this process to be completed.\");\n    return false;\n  }\n\n  error = false;\n  form = form_name;\n  error_message = \"Errors have occured during the process of your form.\\n\\nPlease make the following corrections:\\n\\n\";\n\n\n  check_input(\"firstname\", 2, \"Your First Name must contain a minimum of 2 characters.\");\n  check_input(\"lastname\", 2, \"Your Last Name must contain a minimum of 2 characters.\");\n\n\n  check_input(\"email_address\", 6, \"Your E-Mail Address must contain a minimum of 6 characters.\");\n  check_input(\"street_address\", 5, \"Your Street Address must contain a minimum of 5 characters.\");\n  check_input(\"postcode\", 4, \"Your Zip Code must contain a minimum of 4 characters.\");\n  check_input(\"city\", 3, \"Your City must contain a minimum of 3 characters.\");\n\n  check_input(\"state\", 2, \"Your State must contain a minimum of 2 characters.\");\n\n  check_select(\"country\", \"\", \"You must select a country from the Countries pull down menu.\");\n\n  check_input(\"telephone\", 3, \"Your Telephone Number must contain a minimum of 3 characters.\");\n\n  check_password(\"password\", \"confirmation\", 5, \"Your Password must contain a minimum of 5 characters.\", \"The Password Confirmation must match your Password.\");\n  check_password_new(\"password_current\", \"password_new\", \"password_confirmation\", 5, \"Your Password must contain a minimum of 5 characters.\", \"Your new Password must contain a minimum of 5 characters.\", \"The Password Confirmation must match your new Password.\");\n\n  if (error == true) {\n    alert(error_message);\n    return false;\n  } else {\n    submitted = true;\n    return true;\n  }\n}\nfunction refresh_form(form_name) {\n   form_name.action.value = 'refresh';\n   form_name.state.value = '';\n   form_name.submit();\n   return true;\n   }\n\/\/ ]]><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\nfunction popupWindow(url) {\n  window.open(url,'popupWindow','toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=no,resizable=yes,copyhistory=no,width=100,height=100,screenX=150,screenY=150,top=150,left=150')\n}\n\/\/ ]]><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\nfunction dropdown(mySel)\n{\nvar myWin, myVal;\nmyVal = mySel.options[mySel.selectedIndex].value;\nif(myVal)\n   {\n   if(mySel.form.target)myWin = parent[mySel.form.target];\n   else myWin = window;\n   if (! myWin) return true;\n   myWin.location = myVal;\n   }\nreturn false;\n}\n\/\/ ]]><\/script><script src=\"..\/..\/..\/SpryAssets\/SpryMenuBar.js\" type=\"text\/javascript\"><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\nfunction CVVPopUpWindow(url) {\n\twindow.open(url,'popupWindow','toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=no,resizable=no,copyhistory=no,width=600,height=233,screenX=150,screenY=150,top=150,left=150')\n}\n\/\/ ]]><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\nfunction popupImage(url, imageHeight, imageWidth) {\n\t\tvar newImageHeight = (parseInt(imageHeight) + 40);\n\t\tvar yPos = ((screen.height \/ 2) - (parseInt(newImageHeight) \/ 2));\n\t\tvar xPos = ((screen.width \/ 2) - (parseInt(imageWidth) \/ 2));\n\t\timageWindow = window.open(url,'popupImages','toolbar=no,location=no,directories=no,status=yes,menubar=no,scrollbars=no,resizable=yes,copyhistory=no,width=' + imageWidth + ',height=' + newImageHeight + ',screenY=' + yPos + ',screenX=' + xPos + ',top=' + yPos + ',left=' + xPos);\n\n\t\timageWindow.moveTo(xPos, yPos);\n\t\timageWindow.resizeTo(parseInt(imageWidth), parseInt(newImageHeight));\n\n\t\tif (window.focus) {\n\t\t\timageWindow.focus();\n\t\t}\n\t}\n\/\/ ]]><\/script><script>\/\/ <![CDATA[\n  (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){\n  (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o),\n  m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m)\n  })(window,document,'script','\/\/www.google-analytics.com\/analytics.js','ga');\n\n  ga('create', 'UA-7993642-5', 'auto');\n  ga('require', 'displayfeatures');\n  ga('send', 'pageview');\n\/\/ ]]><\/script><script type=\"text\/javascript\">\/\/ <![CDATA[\n$.ajax({\n  url: '\/\/munchkin.marketo.net\/munchkin.js',\n  dataType: 'script',\n  cache: true,\n  success: function() {\n    Munchkin.init('666-JYP-033');\n  }\n});\n\/\/ ]]><\/script><\/p>\n<p>SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibits angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth factor receptor 2 (FGFR2) and platelet-derived growth factor receptor (PDGFR) at rate of 97%, 65% and 55%, respectively, at concentration of 10 \u03bcM in biochemical kinase assays.SKLB610 exhibits its antitumor activity as a multi-targeted inhibitor with more potent inhibition of VEGFR2 activity.<\/p>\n<table width=\"91%\">\n<tbody>\n<tr>\n<td><a href=\"http:\/\/www.biovision.com\/cancer-research-2608\/angiogenesis-3007\/inhibitors-3011\/index-1-1a.html\">Catalog #<\/a><\/td>\n<td width=\"54%\">\u00a0<a href=\"http:\/\/www.biovision.com\/cancer-research-2608\/angiogenesis-3007\/inhibitors-3011\/index-1-2d.html\">Product Name+<\/a><\/td>\n<td width=\"31%\">\u00a0<a href=\"http:\/\/www.biovision.com\/cancer-research-2608\/angiogenesis-3007\/inhibitors-3011\/index-1-3a.html\">Size<\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a02367-250<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/borrelidin-7007.html\">Borrelidin<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a0250 \u00b5g<\/td>\n<\/tr>\n<tr>\n<td>\u00a02367-1000<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/borrelidin-7008.html\">Borrelidin<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a01 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02293-10<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/castanospermine-6604.html\">Castanospermine<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a010 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02293-50<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/castanospermine-6605.html\">Castanospermine<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a050 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09476-5<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/foretinib-10131.html\">Foretinib<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a09476-25<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/foretinib-10132.html\">Foretinib<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a025 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02368-1<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/fumagillin-7009.html\">Fumagillin<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a01 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02529-5<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/isoxanthohumol-8244.html\">Isoxanthohumol<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02529-25<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/isoxanthohumol-8245.html\">Isoxanthohumol<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a025 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02610-5<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/sklb610-8640.html\">SKLB610<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a05 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a02610-25<\/td>\n<td width=\"54%\">\u00a0<strong><a href=\"http:\/\/www.biovision.com\/sklb610-8641.html\">SKLB610<\/a><\/strong><\/td>\n<td width=\"31%\">\u00a025 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><strong>\u764c\u75c7\u884c\u70ba\u76f8\u95dc\u5546\u54c1<\/strong><\/p>\n<p><strong>Invasion<\/strong><strong>\u7d30\u80de\u4fb5\u5165\u5206\u6790<\/strong><strong> | Migration<\/strong><strong>\u7d30\u80de\u9077\u79fb<\/strong><strong> | <\/strong><strong>\u6297\u764c\u85e5\u5291<\/strong><strong> | DIVAA<\/strong><strong>\u6d3b\u9ad4\u8840\u7ba1\u65b0\u751f\u6210\u5957\u7d44<\/strong><strong> | Warburg<\/strong><strong>\u74e6\u6c0f\u6548\u61c9<\/strong><strong> | <\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8840\u7ba1\u65b0\u751f\u6291\u5236\u5291SKLB610 \u00a0\u8ca8\u865f2610-25 \u00a0| 25 mg \u7522\u54c1\u63cf\u8ff0: Biovision\u63d0\u4f9b\u4e00\u7cfb\u5217 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":6354,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[478,191,127],"tags":[4526],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6358"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6358"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6358\/revisions"}],"predecessor-version":[{"id":6360,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/6358\/revisions\/6360"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/6354"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6358"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}