{"id":54991,"date":"2026-08-12T17:07:57","date_gmt":"2026-08-12T09:07:57","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=54991"},"modified":"2026-08-12T17:07:57","modified_gmt":"2026-08-12T09:07:57","slug":"doxorubicin-adriamycin-hcl-cas25316-40-9-apexbio%e8%b2%a8%e8%99%9fa1832","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=54991","title":{"rendered":"Doxorubicin (Adriamycin) HCl | CAS#25316-40-9 APExBIO\u8ca8\u865fA1832"},"content":{"rendered":"

\u84bd\u74b0\u985e\u6297\u751f\u7d20\u884d\u751f\u7269\u7cfb\u5217\u5546\u54c1->>Doxorubicin (Adriamycin) HCl<\/span>
\n<\/span><\/span><\/span><\/strong><\/p>\n

APExBIO Technology LLC \u662f\u4e00\u5bb6\u9818\u5148\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5291 (Small Molecule Inhibitors)\/\u6d3b\u5316\u5291(Activators)\u3001\u5316\u5408\u7269\u5eab( Compound Libraries)\u3001\u80dc\u80bd(Peptides)\u3001\u6aa2\u6e2c\u8a66\u5291\u76d2(Assay Kits)\u3001\u87a2\u5149\u6a19\u8a18(Fluorescent Label)\u3001\u9176(Enzymes)\u3001\u4fee\u98fe\u6838\u82f7\u9178(Modified Nucleotides)\u3001mRNA \u5408\u6210\u4ee5\u53ca\u5404\u7a2e\u5206\u5b50\u751f\u7269\u5b78\u5de5\u5177\u7684\u4f9b\u61c9\u5546\u3002APExBIO\u63d0\u4f9b\u5ee3\u6cdb\u7684\u7522\u54c1\u7dda\uff0c\u6db5\u84cb 20 \u591a\u500b\u4e0d\u540c\u7684\u7814\u7a76\u9818\u57df\uff0c\u4f8b\u5982\u764c\u75c7(cancer)\u3001\u514d\u75ab\u5b78(immunology)\u3001\u795e\u7d93\u79d1\u5b78(neurosciences)\u3001\u7d30\u80de\u51cb\u4ea1(apoptosis)\u548c\u8868\u89c0\u907a\u50b3\u5b78(epigenetics)\u7b49\u3002\u516c\u53f8\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u5fb7\u5dde\u4f11\u58eb\u9813USA (Houston, Texas)\uff0c\u81f4\u529b\u65bc\u670d\u52d9\u5168\u7403\u5ba2\u6236\u3002\u9ad8\u5ea6\u91cd\u8996\u7522\u54c1\u54c1\u8cea\u3002\u6240\u6709\u7522\u54c1\u5747\u9075\u5faa\u56b4\u683c\u7684\u751f\u7522\u6307\u5357\uff0c\u4e26\u9644\u6709\u5206\u6790\u8b49\u66f8\u3001HPLC\u3001\u8cea\u8b5c(Mass Spectrum)\u548cHMNR\u4ee5\u53ca\u9ad4\u5916\u9a57\u8b49(in vitro validation)\u3002 APExBIO\u7522\u54c1\u5df2\u88ab\u300aNature\u300b\u3001\u300aCell\u300b\u548c\u300aScience\u300b\u7b49\u773e\u591a\u9802\u7d1a\u540c\u884c\u8a55\u5be9\u671f\u520a\u5f15\u7528\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

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Doxorubicin (Adriamycin) HCl | CAS#25316-40-9 APExBIO\u8ca8\u865fA1832<\/span><\/strong><\/span><\/a><\/span><\/p>\n

DNA topoisomerase II inhibitor<\/span><\/p>\n

Doxorubicin hydrochloride (CAS 25316-40-9\uff09\u662f\u4e00\u7a2e\u84bd\u74b0\u985e\u6297\u751f\u7d20\u884d\u751f\u7269( anthracycline antibiotic derivative)\uff0c\u5177\u6709\u7d30\u80de\u6bd2\u6027\u6d3b\u6027( cytotoxic activity)\uff0c\u88ab\u5ee3\u6cdb\u7528\u4f5c\u6297\u764c\u5316\u7642\u85e5\u7269( anticancer chemotherapeutic agent)\u3002\u5176\u4f5c\u7528\u6a5f\u8f49\u5305\u62ec\u5d4c\u5165DNA\u96d9\u80a1\u3001\u6291\u5236DNA\u62d3\u6a38\u7570\u69cb\u9176II\u7684\u6d3b\u6027\uff0c\u9032\u800c\u963b\u65b7\u8907\u88fd\u904e\u7a0b\uff0c\u4e26\u85c9\u7531\u7f6e\u63db\u7d44\u86cb\u767d\u5c0e\u81f4DNA\u640d\u50b7\u53ca\u67d3\u8272\u8cea\u7d50\u69cb\u6539\u8b8a\u3002\u5728\u751f\u7269\u91ab\u5b78\u7814\u7a76\u4e2d\uff0cDoxorubicin hydrochloride (CAS 25316-40-9\uff09\u5e38\u7528\u65bc\u9ad4\u5916\u5be6\u9a57\u53ca\u52d5\u7269\u6a21\u578b\uff0c\u4ee5\u7814\u7a76\u91dd\u5c0d\u8840\u6db2\u60e1\u6027\u816b\u7624\u3001\u5be6\u9ad4\u816b\u7624\u548c\u8089\u7624\u7684\u6cbb\u7642\u7b56\u7565\u3002\u5176IC50\u503c\u56e0\u7d30\u80de\u985e\u578b\u548c\u6e2c\u5b9a\u689d\u4ef6\u800c\u7570\uff0c\u5728\u5404\u985e\u6e90\u81ea\u816b\u7624\u7684\u7d30\u80de\u6a21\u578b\u4e2d\uff0c\u901a\u5e38\u5728\u7d040.1 \u00b5M\u81f32 \u00b5M\u7684\u7bc4\u570d\u5167\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Physical Appearance<\/td>\nA solid<\/td>\n<\/tr>\n
Storage<\/td>\nStore at -20\u00b0C<\/td>\n<\/tr>\n
M.Wt<\/td>\n579.98<\/td>\n<\/tr>\n
Cas No.<\/td>\n25316-40-9<\/td>\n<\/tr>\n
Formula<\/td>\nC27<\/sub>H29<\/sub>NO11<\/sub>\u00b7HCl<\/td>\n<\/tr>\n
Solubility<\/td>\n\u226529 mg\/mL in DMSO; \u226557.2 mg\/mL in H2O; insoluble in EtOH<\/td>\n<\/tr>\n
Chemical Name<\/td>\n(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride<\/td>\n<\/tr>\n
Canonical SMILES<\/td>\nCOC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl<\/td>\n<\/tr>\n
Shipping Condition<\/td>\nSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.<\/td>\n<\/tr>\n
General tips<\/td>\nWe do not recommend long-term storage for the solution, please use it up soon.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u54c1\u9805<\/td>\nCAS#<\/td>\n#\u8ca8\u865f<\/td>\n\u61c9\u7528<\/td>\n<\/tr>\n
Romidepsin (FK228, depsipeptide)<\/a><\/td>\n\n

CAS#128517-07-7<\/p>\n

 <\/td>\n

\u8ca8\u865fA8173<\/td>\nHDAC1\/HDAC2\uff0c\u5f37\u6548\u548c\u9078\u64c7\u6027\u6291\u5236\u5291<\/td>\n<\/tr>\n
Pirarubicin<\/a><\/td>\nCAS#72496-41-4<\/td>\n\u8ca8\u865fB2295<\/td>\n\u00a0anthracycline anti-neoplastic doxorubicin<\/td>\n<\/tr>\n
Tunicamycin<\/a><\/td>\nCAS# 15663-27-1<\/td>\n\n

\u8ca8\u865fA8321<\/p>\n

 <\/td>\n

\u9ad8\u6548\u3001\u5ee3\u8b5c\u7684\u5316\u7642\u85e5\u7269<\/td>\n<\/tr>\n
Azithromycin<\/a><\/td>\nCAS#83905-01-5<\/td>\n\u00a0\u8ca8\u865fA2213<\/td>\nHsp90 inhibitor<\/td>\n<\/tr>\n
Bleomycin Sulfate<\/a><\/td>\n\n

CAS# 9041-93-4<\/p>\n

 <\/td>\n

\u8ca8\u865fB1398<\/td>\nAntibiotic by inhibiting protein synthesis<\/td>\n<\/tr>\n
Nystatin (Fungicidin)<\/a><\/td>\nCAS#1400-61-9<\/td>\n\u8ca8\u865fB1993<\/td>\nantifungal antibiotic<\/td>\n<\/tr>\n
Rapamycin<\/a><\/td>\nCAS#53123-88-9<\/td>\n\u8ca8\u865fA8167<\/td>\nOriginal antifungal antibiotic<\/td>\n<\/tr>\n
Daptomycin<\/a><\/td>\nCAS#103060-53-3<\/td>\n\u8ca8\u865fA1206<\/td>\nCalcium-dependent antibiotic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

\"APExBIO_logo\"<\/a><\/p>\n

APExBIO\u53f0\u7063\u4ee3\u7406\u5546:\u00a0 <\/span><\/span><\/strong><\/span><\/a>https:\/\/www.apexbt.com\/<\/span><\/span><\/a><\/span><\/p>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002>>\u66f4\u591aAPExBio\u5546\u54c1<\/span><\/strong><\/em><\/span><\/a><\/p>\n

<\/p>\n

APExBIO\u53f0\u7063\u4ee3\u7406\u5546<\/a><\/span><\/h2>\n

APExBIO\u63d0\u4f9b\u512a\u8cea\u7684\u80dc\u80bd\u548c\u751f\u7269\u5206\u6790\u8a66\u5291\uff0c\u5ee3\u6cdb\u7522\u54c1\u7dda\u5982Protease\u3001Chromatin\/Epigenetics\u8868\u89c0\u907a\u50b3\u5b78\u3001MAPK Signal\u3001DNA Damege\/DNA repair\u3001\u7d30\u80de\u51cb\u4ea1\u3001\u816b\u7624\u751f\u7269\u5b78\u3001Stem cell\u7b49\u7814\u7a76\u9818\u57df\uff0c \u9084\u63d0\u4f9b\u5b9a\u5236\u7684\u670d\u52d9\uff0c\u5305\u62ec\u591a\u80bd\u5408\u6210\uff0c\u6297\u9ad4\u7684\u751f\u7522\u548c\u6aa2\u6e2c\u7684\u767c\u5c55\u3002\u7522\u54c1\u7ddaDNA\/RNA prep kit\u3001Drug Screening panel\u3001Bioactive peptides\u3001Growth factors\u3001Biotinylation Reagents\u3001tag peptides\u3001amino Acids\u3001Growth factors\u7b49\u3002APExBIO\u7522\u54c1\u8cea\u91cf\u90fd\u4f34\u96a8\u8457\u8b49\u66f8\u7684\u5206\u6790\uff0c\u9ad8\u6548\u6db2\u76f8\u8272\u8b5c\uff0c\u8cea\u8b5c\uff0c\u548cHMNR\u6578\u64da\u3002<\/p>\n

\u00a0<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
\u54c1\u9805<\/td>\nCAS#<\/td>\n#\u8ca8\u865f<\/td>\n\u61c9\u7528<\/td>\n<\/tr>\n
Romidepsin (FK228, depsipeptide)<\/a><\/td>\n\n

CAS#128517-07-7<\/p>\n

 <\/td>\n

\u8ca8\u865fA8173<\/td>\nHDAC1\/HDAC2\uff0c\u5f37\u6548\u548c\u9078\u64c7\u6027\u6291\u5236\u5291<\/td>\n<\/tr>\n
Pirarubicin<\/a><\/td>\nCAS#72496-41-4<\/td>\n\u8ca8\u865fB2295<\/td>\n\u00a0anthracycline anti-neoplastic doxorubicin<\/td>\n<\/tr>\n
Tunicamycin<\/a><\/td>\nCAS# 15663-27-1<\/td>\n\n

\u8ca8\u865fA8321<\/p>\n

 <\/td>\n

\u9ad8\u6548\u3001\u5ee3\u8b5c\u7684\u5316\u7642\u85e5\u7269<\/td>\n<\/tr>\n
Azithromycin<\/a><\/td>\nCAS#83905-01-5<\/td>\n\u00a0\u8ca8\u865fA2213<\/td>\nHsp90 inhibitor<\/td>\n<\/tr>\n
Bleomycin Sulfate<\/a><\/td>\n\n

CAS# 9041-93-4<\/p>\n

 <\/td>\n

\u8ca8\u865fB1398<\/td>\nAntibiotic by inhibiting protein synthesis<\/td>\n<\/tr>\n
Nystatin (Fungicidin)<\/a><\/td>\nCAS#1400-61-9<\/td>\n\u8ca8\u865fB1993<\/td>\nantifungal antibiotic<\/td>\n<\/tr>\n
Rapamycin<\/a><\/td>\nCAS#53123-88-9<\/td>\n\u8ca8\u865fA8167<\/td>\nOriginal antifungal antibiotic<\/td>\n<\/tr>\n
Daptomycin<\/a><\/td>\nCAS#103060-53-3<\/td>\n\u8ca8\u865fA1206<\/td>\nCalcium-dependent antibiotic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u84bd\u74b0\u985e\u6297\u751f\u7d20\u884d\u751f\u7269\u7cfb\u5217\u5546\u54c1->>Doxorubicin (Adriamycin) HCl APEx […]<\/p>\n","protected":false},"author":3,"featured_media":47343,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5368],"tags":[],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/54991"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=54991"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/54991\/revisions"}],"predecessor-version":[{"id":54992,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/54991\/revisions\/54992"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/47343"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=54991"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=54991"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=54991"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}