{"id":50683,"date":"2025-03-07T10:22:51","date_gmt":"2025-03-07T02:22:51","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=50683"},"modified":"2025-08-11T17:58:25","modified_gmt":"2025-08-11T09:58:25","slug":"anti-ttf1-nkx2-1-antibody-ep1584y%e5%96%ae%e6%a0%aa%e6%8a%97%e9%ab%94-anti-ttf1-nkx2-1-antibody-ep1584y-%e8%b2%a8%e8%99%9fab76013","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=50683","title":{"rendered":"Anti-TTF1\/Nkx2-1 antibody [EP1584Y]\u55ae\u682a\u6297\u9ad4\u00a0 \u00a0| Anti-TTF1\/Nkx2-1 antibody [EP1584Y] \u8ca8\u865fab76013\u00a0"},"content":{"rendered":"

Anti-TTF1\/Nkx2-1 antibody [EP1584Y]\u55ae\u682a\u6297\u9ad4\u00a0 \u00a0| Anti-TTF1\/Nkx2-1 antibody [EP1584Y] \u8ca8\u865fab76013\u00a0<\/span><\/strong><\/a><\/span><\/p>\n

\"ABCAM_\u5de5\u4f5c\u5340\u57df<\/p>\n

\u6297 TTF1\/Nkx2-1 \u6297\u9ad4 [EP1584Y] ab76013 \u662f\u4e00\u7a2e\u5154\u55ae\u682a\u6297\u9ad4\uff0c\u7528\u65bc TTF1\/Nkx2-1 \u86cb\u767d\u8cea\u5370\u8de1\u548c IHC\u3002\u9069\u7528\u65bc\u4eba\u985e\u3001\u5c0f\u9f20\u548c\u5927\u9f20\u6a23\u672c\u3002<\/p>\n

\u6d3b\u6027\u6458\u8981 TTF1 \u4e5f\u7a31\u70ba Nkx2-1 \u662f\u4e00\u7a2e\u8f49\u9304\u56e0\u5b50\uff0c\u5206\u5b50\u91cf\u7d04 38 kDa\u3002\u5b83\u5728\u8abf\u7bc0\u57fa\u56e0\u8868\u73fe\u65b9\u9762\u767c\u63ee\u91cd\u8981\u4f5c\u7528\u3002\u6b64\u6a19\u9776\u4e3b\u8981\u8868\u9054\u65bc\u7532\u72c0\u817a\u3001\u80ba\u548c\u5927\u8166\u7b49\u7d44\u7e54\u3002\u5728\u7532\u72c0\u817a\u4e2d\uff0c\u5b83\u6703\u6d3b\u5316\u8207\u7532\u72c0\u817a\u6fc0\u7d20\u5408\u6210\u76f8\u95dc\u7684\u57fa\u56e0\uff0c\u800c\u5728\u80ba\u90e8\uff0c\u5b83\u8abf\u7bc0\u5c0d\u80ba\u90e8\u767c\u80b2\u548c\u529f\u80fd\u91cd\u8981\u7684\u57fa\u56e0\u3002\u5b83\u4e5f\u6709\u5176\u4ed6\u66ff\u4ee3\u540d\u7a31\uff0c\u4f8b\u5982\u6297 TTF1 \u548c NKX2.1\u3002\u751f\u7269\u5b78\u529f\u80fd\u7e3d\u7d50 TTF1\/Nkx2-1 \u5c0d\u65bc\u5668\u5b98\u7279\u7570\u6027\u7684\u767c\u80b2\u548c\u7dad\u6301\u81f3\u95dc\u91cd\u8981\u3002\u5b83\u662f\u8f49\u9304\u8907\u5408\u7269\u7684\u95dc\u9375\u7d44\u6210\u90e8\u5206\uff0c\u5728\u7532\u72c0\u817a\u548c\u80ba\u7d44\u7e54\u767c\u80b2\u904e\u7a0b\u4e2d\u8abf\u7bc0\u57fa\u56e0\u7684\u8868\u9054\u3002 TTF1\/Nkx2-1 \u900f\u904e\u63a7\u5236\u53c3\u8207\u5206\u5316\u7684\u57fa\u56e0\u4f86\u5f71\u97ff\u7d30\u80de\u904e\u7a0b\u3002\u5176\u8abf\u7bc0\u529f\u80fd\u5728\u6c7a\u5b9a\u7d30\u80de\u547d\u904b\u6c7a\u5b9a\u548c\u7dad\u6301\u5668\u5b98\u7279\u6027\u65b9\u9762\u767c\u63ee\u91cd\u8981\u4f5c\u7528\u9014\u5f91 TTF1\/Nkx2-1 \u7684\u6d3b\u6027\u6574\u5408\u5230 TGF-\u03b2 \u8a0a\u865f\u50b3\u5c0e\u548c Wnt \u9014\u5f91\u4e2d\u3002\u9019\u4e9b\u9014\u5f91\u5c0d\u65bc\u7d30\u80de\u589e\u751f\u548c\u5206\u5316\u81f3\u95dc\u91cd\u8981\u3002 TTF1\/Nkx2-1 \u8207 TGF-\u03b2 \u8def\u5f91\u4e2d\u7684 SMAD \u7b49\u86cb\u767d\u8cea\u76f8\u4e92\u4f5c\u7528\uff0c\u5f71\u97ff\u7d30\u80de\u53cd\u61c9\u3002\u985e\u4f3c\u5730\uff0c\u5b83\u8207 Wnt \u8def\u5f91\u4e2d\u7684 \u03b2-\u9023\u74b0\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\uff0c\u6709\u52a9\u65bc\u8abf\u7bc0\u8207\u767c\u80b2\u904e\u7a0b\u76f8\u95dc\u7684\u57fa\u56e0\u8868\u73fe\u3002\u76f8\u95dc\u75be\u75c5\u548c\u7d0a\u4e82 TTF1\/Nkx2-1 \u8207\u80ba\u764c\u548c\u5148\u5929\u6027\u7532\u72c0\u817a\u529f\u80fd\u6e1b\u9000\u75c7\u7b49\u75be\u75c5\u6709\u95dc\u3002\u6b64\u8f49\u9304\u56e0\u5b50\u7684\u8868\u9054\u6539\u8b8a\u6216\u7a81\u8b8a\u53ef\u80fd\u5c0e\u81f4\u9019\u4e9b\u75be\u75c5\u3002\u4f8b\u5982\uff0c\u5728\u80ba\u764c\u4e2d\uff0cTTF1\/Nkx2-1 \u7684\u7570\u5e38\u8868\u73fe\u53ef\u80fd\u6d89\u53ca\u8af8\u5982 EGFR \u7b49\u6709\u52a9\u65bc\u816b\u7624\u767c\u751f\u7684\u86cb\u767d\u8cea\u3002\u5728\u5148\u5929\u6027\u7532\u72c0\u817a\u529f\u80fd\u4f4e\u4e0b\u75c7\u4e2d\uff0cTTF1\/Nkx2-1 \u6d3b\u6027\u7684\u7834\u58de\u6703\u5f71\u97ff\u7532\u72c0\u817a\u6fc0\u7d20\u5408\u6210\u76f8\u95dc\u7684\u86cb\u767d\u8cea\uff0c\u9032\u800c\u5f71\u97ff\u4ee3\u8b1d\u904e\u7a0b\u3002<\/p>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df<\/a><\/p>\n

\"Immunohistochemistry<\/p>\n

\n
\n

Immunohistochemistry (Formalin\/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue sections labeling TTF1\/Nkx2-1 with purified ab76013 at 1\/250 dilution (0.6 \u03bcg\/ml). Heat mediated antigen retrieval was performed using EDTA Buffer, PH9. Hematoxylin was used to counter stain.\u00a0Goat Anti-Rabbit IgG H&L (HRP)<\/span>ab97051<\/a>, a Goat Anti-Rabbit IgG H&L (HRP) secondary antibody was used at 1\/500 dilution. PBS instead of the primary antibody was used as the negative control.<\/p>\n<\/div>\n<\/div>\n

\"Immunohistochemistry<\/p>\n

\"Immunohistochemistry<\/p>\n

Immunohistochemistry (Formalin\/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma tissue sections labeling TTF1\/Nkx2-1 with purified ab76013 at 1\/250 dilution (0.6 \u03bcg\/ml). Heat mediated antigen retrieval was performed using EDTA Buffer, PH9. Hematoxylin was used to counter stain.\u00a0Goat Anti-Rabbit IgG H&L (HRP)<\/span>ab97051<\/a>, a Goat Anti-Rabbit IgG H&L (HRP) secondary antibody was used at 1\/500 dilution. PBS instead of the primary antibody was used as the negative control.<\/p>\n

\"Immunohistochemistry<\/p>\n

Immunohistochemical analysis of formalin fixed paraffin embedded human thyroid labelling TTF1 with ab76013 at a concentration of 0.1 \u00b5g\/ml. The immunostaining was performed on a Ventana DISCOVERY ULTRA (Roche Tissue Diagnostics) instrument with a OptiView DAB IHC Detection Kit. Heat mediated antigen retrieval was performed with DISCOVERY cell conditioning solution (CC1) 100\u00b0C, pH 8.5 for 32 mins.<\/p>\n

ab76013 anti-TTF1 [EP1584Y] was incubated for 16 mins at 37\u00b0C. Sections were counterstained with Hematoxylin II. Image inset shows absence of staining in secondary antibody only control.<\/p>\n

\u7522\u54c1\u540d\u7a31<\/span><\/strong><\/span><\/h3>\n

\u6297 TTF1\/Nkx2-1 \u6297\u9ad4 [EP1584Y] ab76013 \u5154\u55ae\u682a\u6297\u9ad4<\/p>\n

\u6297 BRAF\uff08\u7a81\u8b8a\u7684 V600E\uff09\u6297\u9ad4<\/a>\u00a0|\u00a0\u6297 HMGB1 \u6297\u9ad4<\/a>\u00a0|\u00a0\u6297 EGFR \u6297\u9ad4 [EP38Y]\u00a0<\/a>\u00a0|\u00a0\u6297 NF-kB p65 \u6297\u9ad4\u00a0<\/a>\u00a0|\u00a0\u6297 Ki67 \u6297\u9ad4<\/a>\u00a0|\u00a0IV \u578b\u81a0\u539f\u86cb\u767d\u6297\u9ad4<\/a><\/span><\/strong><\/p>\n

\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716<\/a><\/p>\n

\"\"<\/p>\n

http:\/\/www.abcam.com\/<\/p>\n

Abcam\u8b58\u5225\u3001\u958b\u767c\u548c\u63d0\u4f9b\u9ad8\u8cea\u91cf\u7684\u751f\u7269\u8a66\u5291\u548c\u5de5\u5177\uff0c\u5b83\u5011\u5728\u5305\u62ec\u85e5\u7269\u767c\u73fe\u3001\u8a3a\u65b7\u548c\u57fa\u790e\u7814\u7a76\u5728\u5167\u7684\u5ee3\u6cdb\u9818\u57df\u548c\u61c9\u7528\u4e2d\u5fc5\u4e0d\u53ef\u5c11\u3002Abcam \u5c08\u6ce8\u5404\u7a2e\u7814\u7a76\u3001\u8a3a\u65b7\u53ca\u6cbb\u7642\u7528\u4e4b\u55ae\u682a\u6297\u9ad4\u7684\u958b\u767c\uff0c\u64c1\u6709 RabMAb\u00ae \u5154\u5b50\u55ae\u682a\u6297\u9ad4\u751f\u7522\u6280\u8853\u5c08\u5229\u4e4b\u539f\u59cb\u5ee0\u5546\uff0c\u73fe\u4eca\u70ba Abcam \u7684\u5408\u4f5c\u5925\u4f34\u3002\u8207\u5c0f\u9f20\u55ae\u682a\u6297\u9ad4\u76f8\u6bd4\uff0c\u5154\u5b50\u55ae\u682a\u6297\u9ad4\u5177\u6709\u66f4\u512a\u826f\u7684\u6297\u539f\u8fa8\u8b58\u529b\u3001\u66f4\u5f37\u7684\u89aa\u548c\u529b\u8207\u66f4\u9ad8\u7684\u5c08\u4e00\u5ea6\uff0c\u662f\u60a8\u5be6\u9a57\u7528\u55ae\u682a\u6297\u9ad4\u7684\u6700\u4f73\u9078\u64c7\u3002<\/p>\n

Abcam\u70ba\u4e16\u754c\u4e0a\u4e09\u5206\u4e4b\u4e8c\u7684\u751f\u547d\u79d1\u5b78\u5bb6\u63d0\u4f9b\u8d85\u904e 110,000 \u7a2e\u7522\u54c1\uff0c\u7528\u65bc\u7814\u7a76\u86cb\u767d\u8cea\u9776\u6a19 – \u6db5\u84cb\u6297\u9ad4\u3001\u86cb\u767d\u8cea\u3001\u88c2\u89e3\u7269\u3001\u751f\u7269\u5316\u5b78\u88fd\u54c1\u3001\u8a66\u5291\u76d2\u548c\u6aa2\u6e2c\u8a66\u5291\u76d2\u3002 ABCAM\u5728\u5168\u7403\u7684\u5c08\u696d\u8a2d\u65bd\u4e2d\u751f\u7522\u81ea\u5df1\u7684\u7522\u54c1\uff0c\u4e26\u5f9e 400 \u591a\u500b\u63a1\u8cfc\u5546\u8655\u63a1\u8cfc\u5925\u4f34\u3002\u8207\u751f\u547d\u79d1\u5b78\u884c\u696d\u5408\u4f5c\uff0c\u4fc3\u9032\u672a\u4f86\u85e5\u7269\u7684\u958b\u767c\u3002<\/span><\/p>\n

\u7279\u8272\u7522\u54c1\uff1a9\u842c\u591a\u7a2e\u9ad8\u8cea\u91cf\u4e00\u6297<\/a>\u30012800\u591a\u7a2e\u4e8c\u6297<\/a>\u300190\u5206\u9418\u5feb\u901f\u578b\u53ca\u50b3\u7d71ELISA \u548c\u5339\u914d\u7684\u6297\u9ad4\u5c0d<\/a>\u3001\u6572\u9664\u7d30\u80de\u7cfb\u548c\u88c2\u89e3\u7269<\/a>\u3001\u6fc0\u52d5\u5291\u3001\u62ee\u6297\u5291\u3001\u6fc0\u6d3b\u5291\u548c\u6291\u88fd\u5291<\/a>\uff0cDNA\u7532\u57fa\u5316\u8207\u7d44\u86cb\u767d\u4fee\u98fe\u8a66\u5291\uff0c\u7dda\u7c92\u9ad4\u7814\u7a76\u8a66\u5291\uff0c\u7d30\u80de\u6d3b\u6027\u53ca\u51cb\u4ea1\u7b49\u529f\u80fd\u6aa2\u6e2c\u8a66\u5291\u76d2\uff0c\u4eba\u6e90\u5316\u7d30\u80de\u56e0\u5b50\u53ca\u91cd\u7d44\u86cb\u767d\u7b49\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

Anti-TTF1\/Nkx2-1 antibody [EP1584Y]\u55ae\u682a\u6297\u9ad4\u00a0 \u00a0| Anti-TTF1\/N […]<\/p>\n","protected":false},"author":3,"featured_media":37626,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5261],"tags":[6956],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50683"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=50683"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50683\/revisions"}],"predecessor-version":[{"id":50684,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/50683\/revisions\/50684"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/37626"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=50683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=50683"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=50683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}