{"id":49836,"date":"2024-07-17T11:31:55","date_gmt":"2024-07-17T03:31:55","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=49836"},"modified":"2024-07-18T17:19:54","modified_gmt":"2024-07-18T09:19:54","slug":"dpp-iv-%e6%8a%91%e5%88%b6%e5%8a%91%e7%af%a9%e9%81%b8%e6%aa%a2%e6%b8%ac%e8%a9%a6%e5%8a%91%e7%9b%92-dpp-iv-inhibitor-screening-assay-kit-%e8%b2%a8%e8%99%9fabnovaka1311","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=49836","title":{"rendered":"DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2| DPP (IV) Inhibitor Screening Assay Kit \u8ca8\u865fAbnova\u2122KA1311"},"content":{"rendered":"<p><span style=\"color: #33cccc; font-size: 12pt;\"><strong><a style=\"color: #33cccc;\" href=\"https:\/\/biopioneer.com.tw\/?p=49693&amp;preview=true\"><span style=\"font-size: 12pt;\">DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2| DPP (IV) Inhibitor Screening Assay Kit \u8ca8\u865fAbnova\u2122KA1311<\/span><\/a><\/strong><\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/08\/abnova.png\" width=\"628\" height=\"82\" \/><\/p>\n<p><span style=\"color: #999999;\">96 assays\u00a0<\/span><\/p>\n<p>\u4e8c\u80bd\u57fa\u80bd\u9176IV (Dipeptidyl peptidase IV, DPP (IV))\uff0c\u4e5f\u7a31\u70baCD26\uff08\u5206\u5316\u7c0726 \u6216T \u7d30\u80de\u6d3b\u5316\u6297\u539fCD26\uff09\u6216\u817a\u82f7\u812b\u6c28\u9176\u8907\u5408\u86cb\u767d2(adenosine deaminase complexing protein 2)\u7d50\u5408\u7cd6\u86cb\u767d\u3002\u53ef\u6eb6\u6027\u5f62\u5f0fDPP (IV) \u5b58\u5728\u65bc\u4eba\u985e\u8840\u6e05\u548c\u7cbe\u6db2\u4e2d\uff0c\u5df2\u88ab\u5b9a\u6027\u70ba\u819c\u7d50\u5408\u5f62\u5f0f\u7684\u86cb\u767d\u6c34\u89e3\u884d\u751f\u7269\u3002\u672b\u7aef\u88c2\u89e3X-\u812f\u80fa\u9178\u6216X-\u4e19\u80fa\u9178\u4e8c\u80bd\u3002\u81f3\u5c11\u670963 \u7a2e\u5e95\u7269\u53ef\u4ee5\u8207DPP (IV) \u7279\u7570\u6027\u7d50\u5408\uff0c\u5305\u62ec\u751f\u9577\u56e0\u5b50(growth factors)\u3001\u8da8\u5316\u56e0\u5b50(chemokines)\u3001\u795e\u7d93\u80bd(neuropeptides)\u548c\u8840\u7ba1\u6d3b\u6027\u80dc\u80bd(vasoactive peptides)\u3002 \u9019\u4e9b\u6291\u5236\u5291\u4fc3\u9032\u900f\u904e\u6291\u5236DPP (IV) \u4f86\u7dad\u6301\u8461\u8404\u7cd6\u7a69\u614b\uff0cDPP (IV) \u662f\u8ca0\u8cac\u964d\u89e3\u5169\u7a2e\u95dc\u9375\u8461\u8404\u7cd6\u8abf\u7bc0\u6fc0\u7d20\u7684\u9175\u7d20\uff1a\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u4fc3\u80f0\u5cf6\u7d20\u591a\u80bd(GIP) \u548c\u80f0\u9ad8\u8840\u7cd6\u7d20\u6a23\u80dc\u80bd- 1 (GLP-1)\u3002 GLP-1 \u5ef6\u9577\u80f0\u5cf6\u7d20\u7684\u4f5c\u7528\uff0c\u540c\u6642\u6291\u5236\u5347\u7cd6\u7d20\u7684\u91cb\u653e\u3002\u81e8\u5e8a\u7814\u7a76\u8a55\u4f30\u4e86 DPP (IV) \u6291\u5236\u964d\u4f4e\u80f0\u9ad8\u8840\u7cd6\u7d20\u6c34\u5e73\u3001\u5ef6\u9072\u80c3\u6392\u7a7a\u548c\u523a\u6fc0\u80f0\u5cf6\u7d20\u91cb\u653e\u7684\u6f5b\u529b\u3002 DPP (IV) \u6291\u5236\u5291\u4f3c\u4e4e\u5728\u7b2c 2 \u578b\u7cd6\u5c3f\u75c5\u7684\u6cbb\u7642\u4e2d\u5177\u6709\u51fa\u8272\u7684\u6cbb\u7642\u6f5b\u529b\u3002 DPP (IV) \u5728\u816b\u7624\u751f\u7269\u5b78\u4e2d\u4e5f\u767c\u63ee\u8457\u91cd\u8981\u4f5c\u7528\uff0c\u53ef\u7528\u4f5c\u5404\u7a2e\u764c\u75c7\u7684\u6a19\u8a18\u7269\uff0c\u5176\u7d30\u80de\u8868\u9762\u6216\u8840\u6e05\u4e2d\u7684\u6c34\u5e73\u5728\u67d0\u4e9b\u816b\u7624\u4e2d\u5347\u9ad8\uff0c\u800c\u5728\u53e6\u4e00\u4e9b\u816b\u7624\u4e2d\u964d\u4f4e\u3002<\/p>\n<p><span style=\"font-size: 12pt; color: #800080;\"><strong>\u6aa2\u6e2c\u539f\u7406<\/strong><\/span><\/p>\n<p>DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2 (DPP (IV) Inhibitor Screening Assay Kit \u8ca8\u865fAbnova\u2122KA1311)\u63d0\u4f9b\u4e86\u4e00\u7a2e\u65b9\u4fbf\u7684\u57fa\u65bc\u87a2\u5149\u7684 DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u65b9\u6cd5\u3002\u6b64\u6e2c\u5b9a\u4f7f\u7528\u87a2\u5149\u5e95\u7269 Gly-Pro-Aminomethylcoumarin (AMC) \u4f86\u6e2c\u91cf DPP (IV) \u6d3b\u6027\u3002 DPP \u88c2\u89e3\u80bd\u9375\uff0c\u91cb\u653e\u904a\u96e2\u7684 AMC \u57fa\u5718\uff0c\u7522\u751f\u87a2\u5149\uff0c\u53ef\u4f7f\u7528 350-360 nm \u7684\u6fc0\u767c\u6ce2\u9577\u548c 450-465 nm \u7684\u767c\u5c04\u6ce2\u9577\u9032\u884c\u5206\u6790\u3002<br \/>\nPrinciple of the Assay DPP (IV) Inhibitor Screening Assay Kit provides a convenient fluorescence-based method for screening DPP (IV) inhibitors. The assay uses the fluorogenic substrate, Gly-Pro-Aminomethylcoumarin (AMC), to measure DPP (IV) activity. Cleavage of the peptide bond by DPP releases the free AMC group, resulting in fluorescence that can be analyzed using an excitation wavelength of 350-360 nm and an emission wavelength of 450-465 nm.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/07\/4-DPP-IV-%E6%8A%91%E5%88%B6%E5%8A%91%E7%AF%A9%E9%81%B8%E6%AA%A2%E6%B8%AC%E8%A9%A6%E5%8A%91%E7%9B%92-DPP-IV-Inhibitor-Screening-Assay-Kit-%E8%B2%A8%E8%99%9FAbnova%E2%84%A2KA1311.png\" width=\"420\" height=\"224\" \/><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/07\/5-DPP-IV-%E6%8A%91%E5%88%B6%E5%8A%91%E7%AF%A9%E9%81%B8%E6%AA%A2%E6%B8%AC%E8%A9%A6%E5%8A%91%E7%9B%92DPP-IV-Inhibitor-Screening-Assay-Kit-%E8%B2%A8%E8%99%9FAbnova%E2%84%A2KA1311.png\" \/><\/p>\n<p>DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2<\/p>\n<pre class=\"tw-data-text tw-text-large tw-ta\" dir=\"ltr\" data-placeholder=\"\u7ffb\u8b6f\" data-ved=\"2ahUKEwjHsIzg2ZWCAxVNhlYBHYHMDksQ3ewLegQIBhAQ\"><span class=\"Y2IQFc\" lang=\"zh-TW\">\r\n<img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/07\/2-DPP-IV-%E6%8A%91%E5%88%B6%E5%8A%91%E7%AF%A9%E9%81%B8%E6%AA%A2%E6%B8%AC%E8%A9%A6%E5%8A%91%E7%9B%92DPP-IV-Inhibitor-Screening-Assay-Kit-%E8%B2%A8%E8%99%9FAbnova%E2%84%A2KA1311.png\" \/>\r\n<\/span><a href=\" http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/07\/1-DPP-IV-\u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2DPP-IV-Inhibitor-Screening-Assay-Kit-\u8ca8\u865fAbnova\u2122KA1311.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/pre>\n<p><img decoding=\"async\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2024\/07\/3-DPP-IV-%E6%8A%91%E5%88%B6%E5%8A%91%E7%AF%A9%E9%81%B8%E6%AA%A2%E6%B8%AC%E8%A9%A6%E5%8A%91%E7%9B%92-DPP-IV-Inhibitor-Screening-Assay-Kit-%E8%B2%A8%E8%99%9FAbnova%E2%84%A2KA1311.png\" \/><\/p>\n<div class=\"article-block\">\n<div class=\"article-block\">\n<div class=\"article-block\">\n<div class=\"article-block\">\n<div class=\"article-block\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>DPP (IV) \u6291\u5236\u5291\u7be9\u9078\u6aa2\u6e2c\u8a66\u5291\u76d2| DPP (IV) Inhibitor Screening Assay [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":40950,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5549],"tags":[6623],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/49836"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=49836"}],"version-history":[{"count":2,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/49836\/revisions"}],"predecessor-version":[{"id":49839,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/49836\/revisions\/49839"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/40950"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=49836"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=49836"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=49836"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}