{"id":48156,"date":"2024-01-10T17:49:32","date_gmt":"2024-01-10T09:49:32","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=48156"},"modified":"2024-01-11T10:55:36","modified_gmt":"2024-01-11T02:55:36","slug":"type-i-bovine-collagen-%e8%b2%a8%e8%99%9f1200-02-1200-02s-%e5%87%8d%e4%b9%be%e7%b2%89-%e6%ba%b6%e6%b6%b2","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=48156","title":{"rendered":"Type I Bovine Collagen | \u8ca8\u865f1200-02\/1200-02S (\u51cd\u4e7e\u7c89\/\u6eb6\u6db2)"},"content":{"rendered":"

Type I Bovine Collagen | <\/strong>\u8ca8\u865f1200-02\/1200-02S (\u51cd\u4e7e\u7c89\/\u6eb6\u6db2)<\/strong>\u00a0<\/strong><\/a><\/span>\u898f\u683c0.5 mg\/mL<\/strong><\/p>\n

\u7d30\u80de\u514d\u75ab\u5c08\u5bb6<\/strong>\u6975\u529b\u63a8\u85a6<\/strong>SouthernBiotech<\/strong>\u9ad8\u54c1\u8cea\u81a0\u539f<\/strong>– Type I Collagen<\/strong><\/p>\n

\u95dc\u65bc\u81a0\u539f\uff08Collagen\uff09\uff1a<\/strong><\/p>\n

\u81a0\u539f\u86cb\u767d\u662f\u52d5\u7269\u7d50\u7de0\u7d44\u7e54\u91cd\u8981\u7684\u86cb\u767d\u8cea,\u5728\u54fa\u4e73\u52d5\u7269\u4e2d\u7684\u542b\u91cf\u5c24\u70ba\u8c50\u5bcc\uff0c\u4f54\u6709\u6a5f\u9ad4\u86cb\u767d\u8cea\u767e\u5206\u4e4b25%-35%\u542b\u91cf\u3002\u81a0\u539f\u662f\u7d30\u80de\u5916\u6700\u91cd\u8981\u7684\u6c34\u4e0d\u6eb6\u6027\u7e96\u7dad\u86cb\u767d, \u662f\u69cb\u6210\u7d30\u80de\u5916\u57fa\u8cea\uff08extracellular matrix, ECM\uff09\u7684\u9aa8\u67b6\u3002\u81a0\u539f\u5728\u7d30\u80de\u5916\u57fa\u8cea\u4e2d\u5f62\u6210\u534a\u6676\u9ad4\u7684\u7e96\u7dad,\u7d66\u7d30\u80de\u63d0\u4f9b\u6297\u5f35\u529b\u548c\u5f48\u6027,\u4e26\u5728\u7d30\u80de\u7684\u9077\u79fb\u548c\u767c\u80b2\u4e2d\u8d77\u4f5c\u7528\u3002\u81a0\u539f\u86cb\u767d\u7684\u57fa\u672c\u7d50\u69cb\u55ae\u4f4d\u662f\u539f\u81a0\u539f(tropocollagen), \u539f\u81a0\u539f\u80bd\u93c8\u7684\u4e00\u7d1a\u7d50\u69cb\u5177\u6709(Gly-x-y)n\u91cd\u8907\u5e8f\u5217, \u5176\u4e2dx\u5e38\u70ba\u812f\u6c28\u9178(Pro), y\u5e38\u70ba\u7fa5\u812f\u6c28\u9178(Hypro)\u6216\u7fa5\u8cf4\u6c28\u9178(Hylys)\u3002Hylys\u6b98\u57fa\u53ef\u767c\u751f\u7cd6\u57fa\u5316\u4fee\u98fe,\u5176\u7cd6\u55ae\u4f4d\u6709\u7684\u662f\u4e00\u500b\u534a\u4e73\u7cd6\u6b98\u57fa(Gal), \u4f46\u901a\u5e38\u662f\u4e8c\u7cd6(Glu-Gal-),\u81a0\u539f\u4e0a\u7684\u7cd6\u6240\u5360\u7684\u91cf\u7d04\u70ba\u81a0\u539f\u768410%\u3002\u539f\u81a0\u539f\u662f\u7531\u4e09\u689d\u03b1-\u80bd\u93c8\u7d44\u6210\u7684\u7e96\u7dad\u72c0\u86cb\u767d\u8cea, \u76f8\u4e92\u64f0\u6210\u4e09\u80a1\u87ba\u65cb\u72c0\u69cb\u578b, \u9577300nm, \u76f4\u5f911.5nm\u3002\u76ee\u524d\u5df2\u767c\u73fe29\u7a2e\u4e0d\u540c\u7d44\u7e54\u4e2d\u4e0d\u540c\u985e\u578b\u7684\u81a0\u539f; \u4e0d\u540c\u985e\u578b\u7684\u81a0\u539f\u5b9a\u4f4d\u65bc\u9ad4\u5167\u7684\u7279\u5b9a\u7d44\u7e54,\u4e5f\u67092-3\u7a2e\u4e0d\u540c\u7684\u81a0\u539f\u5b58\u5728\u65bc\u540c\u4e00\u7d44\u7e54\u4e2d\u3002\u800c\u6a5f\u9ad4\u516790%\u7684\u81a0\u539f\u70baI\u3001II\u3001III\u3001IV\u578b\u3002<\/p>\n

\u81a0\u539f\u86cb\u767d(Collagen)\u662f\u7d30\u80de\u5916\u7a7a\u9593\u7684\u4e3b\u8981\u7d50\u69cb\u86cb\u767d\uff0c\u4e5f\u662f ECM \u4e2d\u6700\u8c50\u5bcc\u7684\u86cb\u767d\u8cea\u3002\u81a0\u539f\u86cb\u767d\u5206\u70ba\u5169\u985e – \u539f\u7e96\u7dad\uff08 fibril)\u00a0 I\u3001II\u3001III\u3001V \u578b\uff09\u548c\u975e\u539f\u7e96\u7dad(non-fibril)\uff08IV\u3001VI \u578b\uff09\u3002 I \u578b\u81a0\u539f\u86cb\u767d(Type I collagen)\u662f\u6700\u8c50\u5bcc\u7684\u81a0\u539f\u86cb\u767d\uff0c\u5e7e\u4e4e\u5728\u6240\u6709\u7d50\u7de0\u7d44\u7e54\u4e2d\u8868\u9054\uff0c\u5305\u62ec\u76ae\u819a(skin)\u3001\u808c\u8171(tendon)\u548c\u9aa8\u7d44\u7e54(bone tissue)\u3002\u5b83\u4e5f\u662f\u9593\u9699\u57fa\u8cea(interstitial matrix)\u7684\u4e3b\u8981\u6210\u5206\u3002 I \u578b\u81a0\u539f\u86cb\u767d\u7a81\u8b8a\u8207\u4e00\u7cfb\u5217\u75be\u75c5\u6709\u95dc\uff0c\u5305\u62ec\u6210\u9aa8\u4e0d\u5168\u75c7(osteogenesis imperfecta)\u548c\u57c3\u52d2\u65af-\u7576\u6d1b\u65af\u75c7\u5019\u7fa4(Ehlers\u2013Danlos syndrome)\u3002 I \u578b\u81a0\u539f\u86cb\u767d\u7531\u5169\u689d \u03b11(I) \u93c8\u548c\u4e00\u689d \u03b12(I) \u93c8\u7d44\u6210\u3002<\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Description<\/th>\nCollagen is the main structural protein in the extracellular space and is the most abundant protein in the ECM. Collagens are divided into two classes – fibril (types I, II, III, V) and non-fibril (types IV, VI). Type I collagen is the most abundant collagen and is expressed in almost all connective tissues including skin, tendon, and bone tissue. It is also the predominant component of the interstitial matrix. Type I collagen mutations are associated in a range of diseases including osteogenesis imperfecta and Ehlers\u2013Danlos syndrome. Type I collagen consists of two \u03b11(I) chains and one \u03b12(I) chain.<\/td>\n<\/tr>\n
Source<\/th>\nPlacental villi<\/td>\n<\/tr>\n
Purity<\/th>\n> 90% by SDS-PAGE<\/td>\n<\/tr>\n
Purification Method<\/th>\nControlled and limited pepsin digestion followed by selective salt precipitation<\/td>\n<\/tr>\n
Buffer Formulation<\/th>\n500 mM acetic acid<\/td>\n<\/tr>\n
Concentration<\/th>\n0.5 mg\/mL<\/td>\n<\/tr>\n
Volume<\/th>\n1.0 mL<\/td>\n<\/tr>\n
Recommended Storage<\/th>\n2-8\u00b0C<\/td>\n<\/tr>\n
Applications<\/th>\nELISA \u2013 Quality tested
\nSDS-PAGE \u2013 Quality tested
\nSurface Plasmon Resonance \u2013 Reported in literature\u00a02<\/sup>
\nCoating Material for \u2013
\nAdhesion Studies \u2013 Reported in literature\u00a01-3<\/sup>
\nMigration Studies \u2013 Reported in literature\u00a04<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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Citations<\/a><\/span><\/h2>\n<\/div>\n
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  1. 1. Switalski LM, Butcher WG, Caufield PC, Lantz MS. Collagen mediates adhesion of Streptococcus mutans to human dentin. Infect Immun. 1993;61:4119-25. (Coating, Adhesion Studies)<\/li>\n
  2. 2. House-Pompeo K, Boles JO, H\u00f6\u00f6k M. Characterization of bacterial adhesin interactions with extracellular matrix components utilizing biosensor technology. Methods. 1994;6:134-42. (SPR, Coating, Adhesion Studies)<\/li>\n
  3. 3. McGrady JA, Butcher WG, Beighton D, Switalski LM. Specific and charge interactions mediate collagen recognition by oral lactobacilli. J Dent Res. 1995;74:649-57. (Coating, Adhesion Studies)<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
    \n
    <\/div>\n<\/div>\n

    \u81a0\u539f\u86cb\u767d<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    \u7522\u54c1\u540d\u7a31<\/strong><\/td>\n\u7de8\u865f\uff08cat#\uff09<\/strong><\/td>\n\u5305\u88dd\u5f62\u5f0f<\/strong><\/td>\n\u898f\u683c<\/strong><\/td>\n<\/tr>\n
    Type I Human Collagen<\/td>\n1200-01S<\/td>\n\u6eb6\u6db2<\/td>\n0.50mg<\/td>\n<\/tr>\n
    Type I Bovine Collagen<\/td>\n1200-02\/1200-02S<\/td>\n\u51cd\u4e7e\u7c89\/\u6eb6\u6db2<\/td>\n0.25mg\/0.50mg<\/td>\n<\/tr>\n
    Type I Rat Collagen<\/td>\n1200-03\/1200-03S<\/td>\n\u51cd\u4e7e\u7c89\/\u6eb6\u6db2<\/td>\n0.25mg\/0.50mg<\/td>\n<\/tr>\n
    Type II Rat Collagen<\/td>\n1220-02\/1220-02S<\/td>\n\u51cd\u4e7e\u7c89\/\u6eb6\u6db2<\/td>\n0.25mg\/0.50mg<\/td>\n<\/tr>\n
    Type III Human Collagen<\/td>\n1230-01S<\/td>\n\u6eb6\u6db2<\/td>\n0.50mg<\/td>\n<\/tr>\n
    Type III Bovine Collagen<\/td>\n1240-02S<\/td>\n\u6eb6\u6db2<\/td>\n0.50mg<\/td>\n<\/tr>\n
    Type IV Human Collagen<\/td>\n1250-01S<\/td>\n\u6eb6\u6db2<\/td>\n0.50mg<\/td>\n<\/tr>\n
    Type IV Mouse Collagen<\/td>\n1250-04S<\/td>\n\u6eb6\u6db2<\/td>\n0.50mg<\/td>\n<\/tr>\n
    Type IV Bovine Collagen<\/td>\n1260-02<\/td>\n\u51cd\u4e7e\u7c89<\/td>\n0.25mg<\/td>\n<\/tr>\n
    Type V Human Collagen<\/td>\n1270-01\/1270-01S<\/td>\n\u51cd\u4e7e\u7c89\/\u6eb6\u6db2<\/td>\n0.1mg\/0.25mg<\/td>\n<\/tr>\n
    Type V Bovine Collagen<\/td>\n1280-02S<\/td>\n\u6eb6\u6db2<\/td>\n0.25mg<\/td>\n<\/tr>\n
    Type VI Human Collagen<\/td>\n1290-01S<\/td>\n\u6eb6\u6db2<\/td>\n0.25mg<\/td>\n<\/tr>\n
    Type VI Bovine Collagen<\/td>\n1300-02\/1300-02S<\/td>\n\u51cd\u4e7e\u7c89\/\u6eb6\u6db2<\/td>\n0.10mg\/0.25mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u81a0\u539f\u86cb\u767d\u591a\u682a\u6297\u9ad4<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n
    \u7522\u54c1\u540d\u7a31<\/strong><\/td>\n\u7de8\u865f\uff08cat#\uff09<\/strong><\/td>\n\u5305\u88dd\u5f62\u5f0f<\/strong><\/td>\n\u898f\u683c<\/strong><\/td>\n<\/tr>\n
    Goat Anti-Type I Collagen<\/td>\n1310-01\/1310-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n
    Goat Anti-Type II Collagen<\/td>\n1320-01\/1320-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n
    Goat Anti-Type III Collagen<\/td>\n1330-01\/1330-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n
    Goat Anti-Type IV Collagen<\/td>\n1340-01\/1340-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n
    Goat Anti-Type V Collagen<\/td>\n1350-01\/1350-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n
    Goat Anti-Type VI Collagen<\/td>\n1360-01\/1360-08<\/td>\n\u672a\u6a19\u8a18\/\u751f\u7269\u7d20\u5316<\/td>\n0.2mg\/0.2mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u81a0\u539f\u86cb\u767d\u55ae\u682a\u6297\u9ad4<\/strong><\/p>\n\n\n\n\n\n\n\n\n
    \u7522\u54c1\u540d\u7a31<\/strong><\/td>\n\u7de8\u865f\uff08cat#\uff09<\/strong><\/td>\n\u5305\u88dd\u5f62\u5f0f<\/strong><\/td>\n\u898f\u683c<\/strong><\/td>\n<\/tr>\n
    Mouse Anti-Human Type I Collagen<\/td>\n1440(1)-01<\/td>\n\u672a\u6a19\u8a18<\/td>\n0.1mg<\/td>\n<\/tr>\n
    Mouse Anti-Human Type IV Collagen<\/td>\n1460-01<\/td>\n\u672a\u6a19\u8a18<\/td>\n0.1mg<\/td>\n<\/tr>\n
    Mouse Anti-Human Type IV Collagen<\/td>\n1460-02<\/td>\nFITC<\/td>\n0.1mg<\/td>\n<\/tr>\n
    Mouse Anti-Human Type IV Collagen<\/td>\n1460-08<\/td>\nBIOT<\/td>\n0.1mg<\/td>\n<\/tr>\n
    Mouse Anti-Human Type IV Collagen<\/td>\n1460-09<\/td>\nR-PE<\/td>\n0.1mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u61c9\u7528\uff1a<\/strong> ELISA\u3001\u514d\u75ab\u87a2\u5149\u3001\u514d\u75ab\u7d30\u80de\u5316\u5b78\u3001\u514d\u75ab\u7d44\u7e54\u5316\u5b78\uff08\u51b0\u51cd\u5207\u7247\uff09<\/p>\n

    Isotype control <\/strong>\u5206\u578b\u5c0d\u7167\u7d44<\/strong><\/a> | <\/strong>\u5206\u578b\u5c0d\u7167\u7d44\u5957\u7d44<\/strong><\/a> | <\/strong>\u6297\u9ad4\u5206\u578b<\/strong>ELISA <\/strong>\u5957\u7d44<\/strong><\/a> | <\/strong>anti-rabbit <\/strong>\u4e8c\u7d1a\u6297\u9ad4<\/strong><\/a> | <\/strong>anti-mouse<\/strong>\u4e8c\u7d1a\u6297\u9ad4<\/strong><\/a> |<\/strong><\/p>\n

     <\/p>\n","protected":false},"excerpt":{"rendered":"

    Type I Bovine Collagen | \u8ca8\u865f1200-02\/1200-02S (\u51cd\u4e7e\u7c89\/\u6eb6\u6db2)\u00a0\u898f\u683c […]<\/p>\n","protected":false},"author":3,"featured_media":37032,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5381],"tags":[6498],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48156"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=48156"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48156\/revisions"}],"predecessor-version":[{"id":48160,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/48156\/revisions\/48160"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/37032"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=48156"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=48156"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=48156"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}