{"id":45561,"date":"2023-08-31T13:52:06","date_gmt":"2023-08-31T05:52:06","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=45561"},"modified":"2024-06-18T19:14:10","modified_gmt":"2024-06-18T11:14:10","slug":"%e9%95%b7%e9%8f%88%e7%a2%b3%e8%8a%b1%e9%9d%92%e6%9f%93%e6%96%99dio-dioc183-cas34215-57-1-%e8%b2%a8%e8%99%9fbmd0072","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=45561","title":{"rendered":"\u9577\u93c8\u78b3\u82b1\u9752\u67d3\u6599DiO (DiOC18(3)) | CAS#34215-57-1 \u8ca8\u865fBMD0072"},"content":{"rendered":"

\u9577\u93c8\u78b3\u82b1\u9752\u67d3\u6599DiO (DiOC18(3)) | CAS#34215-57-1 \u8ca8\u865fBMD0072<\/span><\/strong><\/a><\/span><\/p>\n

Recommendedworkingconcentrations: 5-10\u03bcM<\/p>\n

DiO \u662f\u4e00\u7a2e\u9577\u93c8\u78b3\u82b1\u9752\u67d3\u6599\u3002\u78b3\u82b1\u9752\u67d3\u6599\u5ee3\u6cdb\u7528\u4f5c Di \u4f86\u6a19\u8a18\u7d30\u80de\u3001\u7d30\u80de\u5668\u3001\u8102\u8cea\u9ad4\u3001\u75c5\u6bd2\u548c\u8102\u86cb\u767d\u3002\u7da0\u8272\u87a2\u5149\u89aa\u8102\u6027\u78b3\u82b1\u9752 DiOC18(3) \u88ab\u5ee3\u6cdb\u7528\u4f5c\u89aa\u8102\u6027\u793a\u8e2a\u5291(lipophilic carbocyanine)\u3002\u5b83\u5728\u6c34\u4e2d\u7684\u87a2\u5149\u5f88\u5f31\uff0c\u4f46\u7576\u647b\u5165\u819c\u4e2d\u6642\u87a2\u5149\u5f88\u9ad8\uff0c\u4e26\u4e14\u5177\u6709\u76f8\u7576\u7684\u5149\u7a69\u5b9a\u6027\u3002\u5b83\u5728\u8102\u8cea\u74b0\u5883\u4e2d\u5177\u6709\u6975\u9ad8\u7684\u6d88\u5149\u4fc2\u6578\u548c\u77ed\u7684\u6fc0\u767c\u614b\u58fd\u547d\uff08~1 \u7d0d\u79d2\uff09\u3002\u4e00\u65e6\u61c9\u7528\u65bc\u7d30\u80de\uff0c\u67d3\u6599\u5c31\u6703\u5728\u8cea\u819c\u5167\u6a6b\u5411\u64f4\u6563\u3002
\n\u78b3\u82b1\u9752\u67d3\u6599\u5ee3\u6cdb\u7528\u4f5c Di \u4f86\u6a19\u8a18\u7d30\u80de\u3001\u7d30\u80de\u5668\u3001\u8102\u8cea\u9ad4\u3001\u75c5\u6bd2\u548c\u8102\u86cb\u767d\u3002\u9577\u93c8\u78b3\u82b1\u9752(Carbocyanine dyes )\u5305\u62ecDiO (DiOC18(3))\u3001DiI (DiIC18(3))\u3001DiD (DiIC18(5)) \u548cDiR\uff0c\u4ee5\u53ca\u4e8c\u70f7\u57fa\u6c28\u57fa\u82ef\u4e59\u70ef\u57fa\u67d3\u6599DiA (4-Di-16-ASP ) \u7528\u65bc\u6a19\u8a18\u819c\u548c\u5176\u4ed6\u758f\u6c34\u7d50\u69cb\u3002DiO\u3001DiI\u3001DiD \u548c DiR \u5206\u5225\u8868\u73fe\u51fa\u660e\u986f\u7684\u7da0\u8272\u3001\u6a59\u8272\u3001\u7d05\u8272\u548c\u7d05\u5916\u87a2\u5149; \u5f9e\u800c\u4fc3\u9032\u6d3b\u7d30\u80de\u7684\u591a\u8272\u6210\u50cf\u548c\u6d41\u5f0f\u7d30\u80de\u8853\u5206\u6790\u3002 DiO \u548c DiI \u53ef\u5206\u5225\u8207\u6a19\u6e96 FITC \u548c TRITC \u6ffe\u5149\u7247\u4e00\u8d77\u4f7f\u7528\u3002\u5176\u4e2d DiI \u53ca\u5176\u985e\u4f3c\u7269\u6700\u5e38\u7528\uff0c\u56e0\u70ba\u5b83\u5011\u901a\u5e38\u8868\u73fe\u51fa\u975e\u5e38\u4f4e\u7684\u7d30\u80de\u6bd2\u6027\u3002\u6b64\u5916\uff0cDiI \u9084\u5ee3\u6cdb\u7528\u65bc\u6e2c\u5b9a\u8102\u86cb\u767d\uff0c\u4f8b\u5982 LDL \u548c HDL\u3002\u89aa\u8102\u6027\u6c28\u57fa\u82ef\u4e59\u70ef\u57fa\u67d3\u6599 DiA \u4e5f\u5e38\u7528\u65bc\u795e\u7d93\u5143\u793a\u8e2a[2]\u3002The green fluorescent, lipophilic carbocyanine DiOC18(3) is widely used as a lipophilic tracer. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane.<\/p>\n

Specification<\/span><\/strong><\/span><\/h3>\n\n\n\n\n\n\n
Product name<\/td>\nDiO (DiOC18(3))<\/a><\/td>\n<\/tr>\n
CAS Number<\/td>\n34215-57-1<\/td>\n<\/tr>\n
Molecular Formula<\/td>\nC5<\/sub>3<\/sub>H8<\/sub>5<\/sub>ClN2<\/sub>O6<\/sub><\/td>\n<\/tr>\n
Alternative<\/td>\nDiO (DiOC18(3)),BMD00072<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Product Properties<\/span><\/strong><\/span><\/h3>\n\n\n\n\n\n\n\n\n\n
Formulation<\/td>\nYellow solid<\/td>\n<\/tr>\n
Features & Benefits<\/td>\n\u2022 \u03bbEX\/\u03bbEm: 484\/501 nm(MeOH)<\/td>\n<\/tr>\n
Molecular weight<\/td>\n882<\/td>\n<\/tr>\n
Usage notes<\/td>\n\u2022 Soluble in ethanol, anhydrous DMSO, and anhydrous DMF, with a solubility of approximately 10 mg\/mL in anhydrous DMSO. When it is difficult to dissolve, it can be properly heated or ultrasonically treated.<\/td>\n<\/tr>\n
Storage instructions<\/td>\nStore at 4\u00b0C. The product can be stored for up to 12 months. Protect from light.<\/td>\n<\/tr>\n
Shipping<\/td>\nGel pack with blue ice.<\/td>\n<\/tr>\n
Precautions<\/td>\nThe product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Additional Information<\/span><\/strong><\/span><\/h3>\n\n\n\n\n
Background<\/td>\nThe green fluorescent, lipophilic carbocyanine DiOC18(3) is widely used as a lipophilic tracer. It is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments. Once applied to cells, the dye diffuses laterally within the plasma membrane.<\/td>\n<\/tr>\n
Alternative<\/td>\nDiO (DiOC18(3)),BMD00072<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Image & description<\/span><\/strong><\/span><\/h3>\n
\n
\n
\"Fig.<\/div>\n

Fig. DiO(DiOC18(3)) structure formula<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u9577\u93c8\u78b3\u82b1\u9752\u67d3\u6599DiO (DiOC18(3)) | CAS#34215-57-1 \u8ca8\u865fBMD0072 Recom […]<\/p>\n","protected":false},"author":3,"featured_media":29551,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5262],"tags":[6172],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45561"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=45561"}],"version-history":[{"count":3,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45561\/revisions"}],"predecessor-version":[{"id":49511,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/45561\/revisions\/49511"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/29551"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=45561"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=45561"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=45561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}