{"id":43255,"date":"2023-07-17T17:48:35","date_gmt":"2023-07-17T09:48:35","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=43255"},"modified":"2025-09-02T15:08:02","modified_gmt":"2025-09-02T07:08:02","slug":"%e3%80%90k-ras-%e7%89%b9%e7%95%b0%e6%80%a7%e9%99%8d%e8%a7%a3%e5%8a%91%e3%80%81%e6%8a%91%e5%88%b6%e5%8a%91%e5%92%8c%e6%8b%ae%e6%8a%97%e5%8a%91%e3%80%91k-ras-specific-degraders-inhibitors-antagonists","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=43255","title":{"rendered":"\u3010K-Ras \u7279\u7570\u6027\u964d\u89e3\u5291\u3001\u6291\u5236\u5291\u548c\u62ee\u6297\u5291\u3011K-Ras Specific Degraders, Inhibitors & Antagonists-MCE"},"content":{"rendered":"

K-Ras \u7279\u7570\u6027\u964d\u89e3\u5291\u3001\u6291\u5236\u5291\u548c\u62ee\u6297\u5291-K-Ras Specific Degraders, Inhibitors & Antagonists<\/b><\/span><\/span><\/strong><\/span><\/p>\n

Kirsten \u5927\u9f20\u8089\u7624\u75c5\u6bd2\u764c\u57fa\u56e0\u540c\u7cfb\u7269 (KRAS) \u662f RAS-MAPK \u901a\u8def\u7684\u539f\u764c\u57fa\u56e0\uff0c\u6709 30% \u7684\u764c\u75c7\u8207 RAS \u57fa\u56e0\u7a81\u8b8a\u904e\u5ea6\u6d3b\u5316\u76f8\u95dc\uff0c\u5176\u4e2d\u6709\u9ad8\u9054 85% \u7684\u6bd4\u4f8b\u662f\u7531 RAS \u86cb\u767d\u7570\u69cb\u9ad4 (Isoform)\u300cKRAS\u300d\u7a81\u8b8a\u6240\u5f15\u8d77\u3002KRAS \u7a81\u8b8a\u5b58\u5728\u65bc\u591a\u7a2e\u5be6\u9ad4\u816b\u7624\u4e2d\uff0c\u5305\u62ec\u80ba\u817a\u764c\u3001\u7d50\u76f4\u8178\u764c\u548c\u5c0e\u7ba1\u80f0\u817a\u764c\u3002\u5728\u00a0KRAS\u00a0\u7a81\u8b8a\u5f15\u8d77\u7684\u816b\u7624\u4e2d\uff0c\u6709\u00a080%\u00a0\u7684\u7a81\u8b8a\u662f\u767c\u751f\u5728\u00a0KRAS\u00a0\u86cb\u767d\u5e8f\u5217\u7684\u7b2c\u00a012\u00a0\u500b\u80fa\u57fa\u9178\u4e0a\uff1aG12D\u00a0(41%)\u3001G12V\u00a0(28%)\u3001G12C\u00a0(14%)\u3002RAS\u81f4\u764c\u57fa\u56e0\u662f\u4eba\u985e\u764c\u75c7\u4e2d\u7a81\u8b8a\u6700\u983b\u7e41\u7684\u81f4\u764c\u57fa\u56e0\uff0c\u4e5f\u662f 1982 \u5e74\u767c\u73fe\u7684\u7b2c\u4e00\u500b\u78ba\u8a8d\u7684\u4eba\u985e\u81f4\u764c\u57fa\u56e0\u3002\u7d93\u904e\u6578\u5341\u5e74\u7684\u7814\u7a76\uff0cShokat \u5be6\u9a57\u5ba4\u5728 2013 \u5e74\u53d6\u5f97\u4e86\u91cd\u5927\u7a81\u7834\uff0c\u8868\u660e\u7531KRAS\u57fa\u56e0\u4e2d\u7684 G12C \u7a81\u8b8a\u53ef\u4ee5\u901a\u904e\u65b0\u767c\u73fe\u7684\u958b\u95dc II \u53e3\u888b\u76f4\u63a5\u6291\u5236\u3002\u57fa\u65bc\u9019\u4e00\u7a81\u7834\u6027\u767c\u73fe\uff0csotorasib (AMG510) \u65bc 2021 \u5e74\u7372\u5f97\u7f8e\u570b\u98df\u54c1\u548c\u85e5\u7269\u7ba1\u7406\u5c40\u7684\u6279\u51c6\uff0c\u6210\u70ba\u7b2c\u4e00\u500b\u76f4\u63a5\u9776\u5411 KRAS \u764c\u86cb\u767d\u6cbb\u7642\u4efb\u4f55 KRAS \u7a81\u8b8a\u764c\u75c7\u7684\u7642\u6cd5\uff0c\u5c24\u5176\u662f\u90a3\u4e9b\u651c\u5e36 KRAS G12C \u7a81\u8b8a\u7684\u764c\u75c7\u3002\u81ea 1960 \u5e74\u4ee3\u767c\u73fe KRAS \u4ee5\u4f86\uff0c\u6700\u8fd1\u5728\u6cbb\u7642 KRAS \u9a45\u52d5\u7684\u764c\u75c7\u60a3\u8005\u65b9\u9762\u9032\u5c55\u751a\u5fae\u3002\u5728\u4e00\u6bb5\u6642\u9593\u5167\uff0c\u4eba\u5011\u8a8d\u70ba\u76f4\u63a5\u9776\u5411 KRAS \u7684\u53ef\u80fd\u6027\u4e0d\u5927\uff0c\u56e0\u6b64\u8a8d\u70ba KRAS \u662f\u201c\u4e0d\u53ef\u6297\u85e5\u7684\u201d\uff0cShokat \u5be6\u9a57\u5ba4\u5728 2013 \u5e74\u767c\u73fe\u4e86 KRAS G12C switch II pocket \uff0c\u5f9e\u800c\u91cd\u632f\u4e86\u5c0d\u76f4\u63a5 KRAS \u6291\u5236\u5291\u7684\u7814\u7a76\u3002<\/p>\n

MCE (MedChem Express)\u00a0<\/span><\/span><\/strong><\/span><\/p>\n

MCE\u7e3d\u90e8\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\uff0c\u63d0\u4f9b\u7a2e\u985e\u9f4a\u5168\u7684\u5316\u5b78\u53ca\u751f\u5316\u7814\u7a76\u7528\u7522\u54c1\uff0c\u5305\u62ec\u5275\u65b0\u7684\u751f\u547d\u79d1\u5b78\u8a66\u5291\uff0creference compounds(\u6a19\u6e96\u5316\u5408\u7269)\uff0cAPIs(\u539f\u6599\u85e5)\u53caNatural compounds(\u5929\u7136\u5316\u5408\u7269)\u4ee5\u63d0\u4f9b\u5be6\u9a57\u5ba4\u6216\u79d1\u5b78\u7814\u7a76\u4e4b\u7528\uff0cMedChemExpress(MCE)\u7522\u54c150000+ \u7279\u7570\u6027\u6291\u5236\u5291\u3001\u5316\u5408\u7269\u5eab\u3001\u91cd\u7d44\u86cb\u767d\uff0c\u5c08\u6ce8\u65bc\u4fe1\u865f\u901a\u8def\u548c\u75be\u75c5\u7814\u7a76\u9818\u57df\u3002\u5168\u7403\u6587\u737b\u5ee3\u6cdb\u5f15\u7528\uff0c\u8cea\u63a7\u9ad4\u7cfb\u56b4\u683c\uff0c\u54c1\u8cea100%\u3002<\/p>\n

K-Ras Specific Degraders, Inhibitors & Antagonists<\/b><\/span><\/div>\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Product Name<\/th>\nK-Ras Selectivity<\/th>\nPurity<\/th>\n<\/tr>\n
Sotorasib<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.94%<\/td>\n<\/tr>\n
Adagrasib<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.93%<\/td>\n<\/tr>\n
MRTX1133<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.42%<\/td>\n<\/tr>\n
BI-2852<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.74%<\/td>\n<\/tr>\n
BI-3406<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.95%<\/td>\n<\/tr>\n
BAY-293<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.06%<\/td>\n<\/tr>\n
LC-2<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
ARS-1620<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.80%<\/td>\n<\/tr>\n
Opnurasib<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.94%<\/td>\n<\/tr>\n
MRTX-1257<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.14%<\/td>\n<\/tr>\n
MRTX0902<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.45%<\/td>\n<\/tr>\n
Divarasib<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.46%<\/td>\n<\/tr>\n
PROTAC K-Ras Degrader-1<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.05%<\/td>\n<\/tr>\n
Sotorasib racemate<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.99%<\/td>\n<\/tr>\n
ARS-853<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.39%<\/td>\n<\/tr>\n
ASP2453<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.04%<\/td>\n<\/tr>\n
ARS-1323-alkyne<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.59%<\/td>\n<\/tr>\n
ARS-1630<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.10%<\/td>\n<\/tr>\n
AZD4625<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.52%<\/td>\n<\/tr>\n
ARS-1323<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.14%<\/td>\n<\/tr>\n
KRAS G12D inhibitor 14<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.39%<\/td>\n<\/tr>\n
G12Si-5 formic<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
K-Ras G12C-IN-2<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.21%<\/td>\n<\/tr>\n
KRAS inhibitor-6<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-8<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-7<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 28<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.94%<\/td>\n<\/tr>\n
KRAS G12C inhibitor 27<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 15<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n99.55%<\/td>\n<\/tr>\n
KRAS G12C inhibitor 32<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
G12Si-1<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-15<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 5<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 18<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 13<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-20<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 17<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12D inhibitor 3<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 16<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 14<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n98.07%<\/td>\n<\/tr>\n
Spiclomazine hydrochloride<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
BI-0474<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRas G12C inhibitor 4<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRas G12C inhibitor 1<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-10<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 23<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 25<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
MRTX849 acid<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 57<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
G12Si-5<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-4<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 50<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
MRTX849 ethoxypropanoic acid<\/b><\/a><\/td>\nSelective Antagonist<\/span><\/td>\n<\/td>\n<\/tr>\n
KRas G12C inhibitor 3<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
K20<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12D inhibitor 7<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12D inhibitor 16<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-9<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRas G12C inhibitor 2<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
PROTAC SOS1 degrader-3<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12D inhibitor 3 TFA<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-11<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 26<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 24<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
6H05<\/b><\/a><\/td>\nSelective Inhibitor<\/span><\/td>\n<\/td>\n<\/tr>\n
MRTX-EX185 formic<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
Pan KRas-IN-1<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n98.47%<\/td>\n<\/tr>\n
SAH-SOS1A TFA<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n99.16%<\/td>\n<\/tr>\n
KRpep-2d<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-10<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n99.86%<\/td>\n<\/tr>\n
KRpep-2d TFA<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n98.11%<\/td>\n<\/tr>\n
KRAS inhibitor-16<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-8<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-14<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 49<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-13<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 52<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-12<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-7<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
RAS-IN-2<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 47<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-15<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 48<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-18<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 55<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 51<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 54<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-17<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
SOS1-IN-6<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
SAH-SOS1A<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 53<\/b><\/a><\/td>\nPan Inhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS inhibitor-3<\/b><\/a><\/td>\nInhibitor<\/td>\n99.65%<\/td>\n<\/tr>\n
RM-018<\/b><\/a><\/td>\nInhibitor<\/td>\n98.03%<\/td>\n<\/tr>\n
Garsorasib<\/b><\/a><\/td>\nInhibitor<\/td>\n99.11%<\/td>\n<\/tr>\n
Atrovastatin-PEG3-FITC<\/b><\/a><\/td>\nInhibitor<\/td>\n98.17%<\/td>\n<\/tr>\n
RMC-6291<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 44<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 46<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
Sotorasib-d7<\/sub><\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
CFL-137<\/b><\/a><\/td>\nInhibitor<\/td>\n99.53%<\/td>\n<\/tr>\n
TUS-007<\/b><\/a><\/td>\nDegrader<\/td>\n<\/td>\n<\/tr>\n
K-Ras(G12C) inhibitor 6<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12D inhibitor 17<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
KRAS G12C inhibitor 43<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
PROTAC SOS1 degrader-2<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
CFL-120<\/b><\/a><\/td>\nInhibitor<\/td>\n\u226598.0%<\/td>\n<\/tr>\n
KRAS G12C inhibitor 45<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/td>\n<\/tr>\n
ZG1077<\/b><\/a><\/td>\nInhibitor<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

K-Ras \u7279\u7570\u6027\u964d\u89e3\u5291\u3001\u6291\u5236\u5291\u548c\u62ee\u6297\u5291-K-Ras Specific Degraders, Inhibito […]<\/p>\n","protected":false},"author":3,"featured_media":52716,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5369],"tags":[5925,5927,6867,6866,6869,6865,5926,6868],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/43255"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=43255"}],"version-history":[{"count":5,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/43255\/revisions"}],"predecessor-version":[{"id":51618,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/43255\/revisions\/51618"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/52716"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=43255"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=43255"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=43255"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}