{"id":42985,"date":"2023-06-09T17:16:54","date_gmt":"2023-06-09T09:16:54","guid":{"rendered":"https:\/\/biopioneer.com.tw\/?p=42985"},"modified":"2023-06-09T17:18:03","modified_gmt":"2023-06-09T09:18:03","slug":"cd31%e9%87%8d%e7%b5%84%e8%9b%8b%e7%99%bd-t-b-cell-surface-proteins-bioworld%e8%b2%a8%e8%99%9fncp0199","status":"publish","type":"post","link":"http:\/\/biopioneer.com.tw\/?p=42985","title":{"rendered":"CD31\u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP0199"},"content":{"rendered":"<p><span style=\"color: #33cccc;\"><a style=\"color: #33cccc;\" href=\"https:\/\/biopioneer.com.tw\/?p=42985&amp;preview=true\"><strong><span style=\"font-size: 12pt;\">CD31\u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP0199<\/span><\/strong><\/a><\/span><\/p>\n<p>CD31 Recombinant Protein<\/p>\n<p>CD31\uff08\u8840\u5c0f\u677f\u5167\u76ae\u7d30\u80de\u7c98\u9644\u5206\u5b50-1\uff1aPlatelet Endothelial Cell Adhesion Molecule-1, PECAM-1\uff09\u662f\u7d30\u80de\u7c98\u9644\u5206\u5b50( cell adhesion molecules) Ig \u8d85\u5bb6\u65cf\u7684\u6210\u54e1\uff0c\u7531\u5faa\u74b0\u8840\u5c0f\u677f(circulating platelets)\u3001\u55ae\u6838\u7d30\u80de(monocytes)\u3001\u55dc\u4e2d\u6027\u7c92\u7d30\u80de(neutrophils)\u3001\u4e00\u4e9b T \u7d30\u80de\u548c\u5167\u76ae\u7d30\u80de\u8868\u9054( endothelial cells)\uff0c\u4e26\u8abf\u7bc0\u7d30\u80de\u7c98\u9644(cell adhesion)\u3001\u5167\u76ae\u7d30\u80de\u9077\u79fb(endothelial cell migration)\u548c\u8840\u7ba1\u751f\u6210(angiogenesis)\u3002\u5728\u5404\u7a2e\u523a\u6fc0\uff08\u4f8b\u5982\u6a5f\u68b0\u6216\u6c27\u5316\u61c9\u6fc0\uff09\u4e0b\uff0cCD31 \u5728\u7d30\u80de\u8cea\u7fa7\u57fa\u672b\u7aef\u5c3e\u90e8\u7684 Tyr686 \u4e0a\u88ab\u78f7\u9178\u5316\uff0c\u63a8\u6e2c\u662f\u7531 Src \u5bb6\u65cf\u6210\u54e1\u5f15\u8d77\u7684\u3002\u916a\u6c28\u9178\u78f7\u9178\u5316( tyrosine phosphorylation )\u4ecb\u5c0e\u8207\u8a31\u591a\u5305\u542b SH2 \u7d50\u69cb\u57df\u7684\u7d50\u5408\u5925\u4f34\u7684\u95dc\u806f\uff0c\u4f8b\u5982 PI3 \u6fc0\u9176( PI3 kinase)\u3001SHIP\u3001PLC\u03b3 \u548c SHP-2\u3002\u56e0\u6b64\uff0cCD31 \u5145\u7576\u5404\u7a2e\u4fe1\u865f\u5206\u5b50\u7684scaffold \u3002<\/p>\n<p><a href=\"https:\/\/bioworlde.com\/\">https:\/\/bioworlde.com\/<\/a><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"\" src=\"https:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/06\/BIOWORLD%E8%A1%A8%E9%9D%A2%E8%9B%8B%E7%99%BD%E8%B3%AA_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1.jpg\" width=\"858\" height=\"226\" \/><\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/downloads\/2023\/06\/1-CD31\u91cd\u7d44\u86cb\u767d-T-B-cell-surface-proteins-BioWorld\u8ca8\u865fNCP0199.pdf\"><img decoding=\"async\" loading=\"lazy\" class=\"alignnone\" src=\"http:\/\/biopioneer.com.tw\/wp-content\/uploads\/2023\/01\/%E7%B6%B2%E7%AB%99%E8%A6%8F%E6%A0%BC%E5%B0%8F%E5%9C%96_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-1_%E5%B7%A5%E4%BD%9C%E5%8D%80%E5%9F%9F-11-300x97.jpg\" alt=\"\u7db2\u7ad9\u898f\u683c\u5c0f\u5716_\u5de5\u4f5c\u5340\u57df 1_\u5de5\u4f5c\u5340\u57df 1\" width=\"149\" height=\"48\" \/><\/a><\/p>\n<table border=\"0\" width=\"100%\">\n<tbody>\n<tr>\n<td>Product Name<\/td>\n<td>CD31 Recombinant Protein<\/td>\n<\/tr>\n<tr>\n<td>Catalog No.<\/td>\n<td>NCP0199<\/td>\n<\/tr>\n<tr>\n<td>Swiss-Prot<\/td>\n<td><a href=\"https:\/\/www.uniprot.org\/uniprot\/P16284\" target=\"_blank\" rel=\"noopener\">P16284<\/a><\/td>\n<\/tr>\n<tr>\n<td>Host<\/td>\n<td>E.coli<\/td>\n<\/tr>\n<tr>\n<td>Tag<\/td>\n<td>His-tag in C-terminal<\/td>\n<\/tr>\n<tr>\n<td>Restriction sites<\/td>\n<td>NdeI-XhoI<\/td>\n<\/tr>\n<tr>\n<td>Background<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Soluble<\/td>\n<td>PBS, 4M Urea, PH7.4<\/td>\n<\/tr>\n<tr>\n<td>Purification&amp;Purity<\/td>\n<td>Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is &gt; 85% (by SDS-PAGE).<\/td>\n<\/tr>\n<tr>\n<td>Concentration<\/td>\n<td>\u22650.5mg\/ml<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b>Product Name :<\/b><br \/>\nCD31 Recombinant Protein<\/p>\n<p><b>Swiss-Prot :<\/b><br \/>\n<a href=\"https:\/\/www.uniprot.org\/uniprot\/P16284\" target=\"_blank\" rel=\"noopener\">P16284<\/a><\/p>\n<p><b>Host :<\/b><br \/>\nE.coli<\/p>\n<p><b>Tag :<\/b><br \/>\n\u22650.5mg\/ml<\/p>\n<p><b>Restriction sites :<\/b><br \/>\nNdeI-XhoI<\/p>\n<p><b>Soluble :<\/b><br \/>\nPBS, 4M Urea, PH7.4<\/p>\n<p><b>Purification&amp;Purity :<\/b><br \/>\nTransferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is &gt; 85% (by SDS-PAGE).<\/p>\n<p><b>Storage&amp;Stability :<\/b><br \/>\nStore at 4\u00b0C short term. Aliquot and store at -20\u00b0C long term. Avoid freeze-thaw cycles.<\/p>\n<p><b>Expression vector :<\/b><br \/>\npet-22b(+)<\/p>\n<p><b>BiowMW :<\/b><br \/>\n~63kDa<\/p>\n","protected":false},"excerpt":{"rendered":"<p>CD31\u91cd\u7d44\u86cb\u767d | T\/B cell surface proteins BioWorld\u8ca8\u865fNCP0199  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":31670,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5799],"tags":[5828],"_links":{"self":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42985"}],"collection":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=42985"}],"version-history":[{"count":1,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42985\/revisions"}],"predecessor-version":[{"id":42986,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/posts\/42985\/revisions\/42986"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=\/wp\/v2\/media\/31670"}],"wp:attachment":[{"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=42985"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=42985"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/biopioneer.com.tw\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=42985"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}